Predictors of multiple dilations and functional outcomes after total laryngectomy and laryngopharyngectomy

BackgroundFollowing total laryngectomy (TL) or laryngopharyngectomy (TLP), patients may develop strictures that require multiple dilations to treat. However, the risk factors associated with dysphagia refractory to a single dilation are unknown.MethodsSingle-institution retrospective review of patients who underwent at least one stricture dilation after TL/TLP between March 2013 and March 2022.ResultsA total of 49 patients underwent stricture dilation after TL/TLP. Thirty-five (71%) underwent multiple dilations. Pharyngocutaneous fistula, primary chemoradiation therapy, and a shorter time interval from TL/TLP to first dilation were independently associated with dysphagia requiring multiple dilations. Patients in the multiple dilations group had a higher rate of limited diet and G-tube dependence compared to patients in the single dilation group.ConclusionsShorter time interval to stricture formation is a prognostic indicator of the need for multiple dilations following TL/TLP. Patients requiring multiple dilations are at increased risk of persistent dysphagia long-term.

Automated summary

The risk factors for dysphagia refractory to a single dilation after TL/TLP include pharyngocutaneous fistula, primary chemoradiation therapy, and a shorter time interval from TL/TLP to first dilation. Patients requiring multiple dilations are at increased risk of persistent dysphagia long-term.