Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 59, Pages 11852-11855Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc04357c
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Funding
- 973 project [2013CB733700]
- National Science Fund for Distinguished Young Scholars [81125023]
- National Natural Science Foundation of China [21202045, 91213303]
- Program of Shanghai Subject Chief Scientist [13XD1404300]
- Key Project of Shanghai Science and Technology Commission [13NM1400900]
- Fundamental Research Funds for Central Universities [222201414010]
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With this research we demonstrate that glycosylation of a naphthalimide zinc ion probe, using click chemistry, leads to an improvement of the aqueous sensitivity, working pH range and targeting ability for specific cells, together with significantly reduced cytotoxicity.
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