4.6 Article

Soluble PD-L1 as a diagnostic and prognostic biomarker in resectable gastric cancer patients

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Prognostic value of soluble PD-L1 and exosomal PD-L1 in advanced gastric cancer patients receiving systemic chemotherapy

Kabsoo Shin et al.

Summary: The study investigated the prognostic significance of soluble PD-L1 (sPD-L1) and exosomal PD-L1 (exoPD-L1) in patients with gastric cancer receiving chemotherapy. It was found that low levels of sPD-L1 and exoPD-L1 were associated with better overall survival and progression-free survival. Pretreatment sPD-L1 could be used as an independent prognostic factor for overall survival, while exoPD-L1 may reflect the immunosuppressive state of patients.

SCIENTIFIC REPORTS (2023)

Article Pathology

Association of PD-1/PD-L1 expression and Epstein--Barr virus infection in patients with invasive breast cancer

Wei-tong Zhang et al.

Summary: This study analyzed the clinicopathological features of EBV-positive IBC and found that EBV infection affects PD-1/PD-L1 expression, similar to other EBV-infected tumors. This finding could be used as a basis to explore therapeutic targets, particularly immunotherapy, for patients with IBC.

DIAGNOSTIC PATHOLOGY (2022)

Article Oncology

Measurement of soluble PD-1 and soluble PD-L1 as well as PD-L1 and PD-1 from perioperative patients with gastric carcinoma

Hangzhi Wei et al.

Summary: This study suggests that soluble PD-1 may play a role in cancer tissues in affecting the prognosis of gastric carcinoma patients. Experimental results indicate that soluble PD-1 could be a promising predictive biomarker for the diagnosis and prognosis of gastric carcinoma patients.

JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2022)

Article Multidisciplinary Sciences

Soluble PD-L1 is a predictive and prognostic biomarker in advanced cancer patients who receive immune checkpoint blockade treatment

So Yeon Oh et al.

Summary: The study revealed that high levels of sPD-L1 in cancer patients were associated with progressive disease and worse prognosis, as well as positively correlated with neutrophil to lymphocyte ratios and negatively correlated with lymphocyte proportions and total numbers.

SCIENTIFIC REPORTS (2021)

Article Oncology

Higher postoperative plasma EV PD-L1 predicts poor survival in patients with gastric cancer

Gaopeng Li et al.

Summary: Postoperative plasma ePD-L1 level is an important prognostic indicator for gastric cancer patients after surgery, with high levels significantly correlating with poor survival, while level changes can bring significant survival benefits.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)

Article Biochemistry & Molecular Biology

TIMER2.0 for analysis of tumor-infiltrating immune cells

Taiwen Li et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Multidisciplinary Sciences

A multi-sample approach increases the accuracy of transcript assembly

Li Song et al.

NATURE COMMUNICATIONS (2019)

Article Gastroenterology & Hepatology

Is high serum programmed death ligand 1 level a risk factor for poor survival in patients with gastric cancer?

Masaaki Ito et al.

ANNALS OF GASTROENTEROLOGICAL SURGERY (2018)

Article Pathology

A protein and mRNA expression-based classification of gastric cancer

Namrata Setia et al.

MODERN PATHOLOGY (2016)

Article Biotechnology & Applied Microbiology

Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Bo Li et al.

GENOME BIOLOGY (2016)

Article Multidisciplinary Sciences

PD-L1 and Survival in Solid Tumors: A Meta-Analysis

Pin Wu et al.

PLOS ONE (2015)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Biotechnology & Applied Microbiology

Differential expression analysis for sequence count data

Simon Anders et al.

GENOME BIOLOGY (2010)

Review Pathology

Laboratory assays for Epstein-Barr virus-related disease

Margaret L. Gulley et al.

JOURNAL OF MOLECULAR DIAGNOSTICS (2008)