Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 20, Pages 4237-4240Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc10413g
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Funding
- NNSFC [21272093, 51473061]
- Fundamental Research Funds for the Central Universities [JCKY-QKJC05]
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A facile strategy to prepare snap-top magnetic nanocarriers has been developed where ultrasmall superparamagnetic Fe3O4 nanoparticles were used as the core with mesoporous silica as the shell followed by the covalent installation of a layer of beta-cyclodextrins on the outer surfaces. The smart hybrid nanomaterials showed remarkable pH- and sugar-responsive cargo release property and low cytotoxicity as proved by an MTT assay with HEK293T cell lines.
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