4.7 Article

A dual-potential electrochemiluminescence ratiometric approach based on graphene quantum dots and luminol for highly sensitive detection of protein kinase activity

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 63, Pages 12669-12672

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc03678j

Keywords

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Funding

  1. National Natural Science Foundation of China [21265012, 21265017, 21475056]
  2. Program for New Century Excellent Talents in University [NCET-11-1002, NCET-13-0848]

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A novel Au NP mediated dual-potential ECL ratiometric approach for highly sensitive protein kinase activity and inhibition assay has been developed based on the simultaneous decrease of cathodic ECL from GQDs and enhancement of anodic ECL from luminol in the same bioanalysis.

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