Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 97, Pages 17301-17304Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc06734k
Keywords
-
Categories
Funding
- ChemBiotech, Munster, Germany
Ask authors/readers for more resources
A new unprecedented metal-mediated base pair was designed that stabilizes reverse Watson-Crick DNA (parallel strand orientation, ps) as well as canonical Watson-Crick DNA (antiparallel strand orientation, aps). This base pair contains two imidazolo-dC units decorated with furan residues. T-m, measurements and spectroscopic studies reveal that each silver-mediated furano-imidazolo-dC forms exceptionally stable duplexes with ps and aps chain orientation. This stability increase by a silver-mediated base pair is the highest reported so far for ps and aps DNA helices.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available