Comparison Between Ocular Biometric Parameters and Intraocular Pressure With and Without Contact Lenses

Objectives:To compare the values of central corneal thickness, anterior chamber depth (ACD), lens thickness (LT), vitreous length (VL), axial length (AL), and corneal-compensated intraocular pressure performed with and without contact lenses (CL).Methods:Forty volunteer participants (16 men and 24 women, 24.2 +/- 2.9 years) were recruited. In a single visit, participants underwent autorefraction, keratometry, biometry, topography, pachymetry, and tonometry with the naked eye (without CL). Then, biometry, pachymetry, and tonometry were repeated twice wearing two CL (somofilcon A and nesofilcon A) fitted in a random order.Results:Many of the ocular biometric values were affected by the use of CL during measurements (paired t test; all P <= 0.003), except for LT and VL (Wilcoxon test; both P >= 0.272). Corneal-compensated intraocular pressure was also affected by contact lens wear during measurements, obtaining lower values when wearing them (Wilcoxon test; all P <= 0.001).Conclusions:Central corneal thickness, ACD, AL, and corneal-compensated intraocular pressure measurements cannot be performed while wearing CL. However, LT and VL measurements were not affected by any contact lens use. In addition, it was observed that ACD results from both devices are not interchangeable either when measured with the naked eye or using any contact lens.

Automated summary

This study compared the measurements of ocular biometric values with and without contact lenses. The results showed that contact lens wear affected several biometric values and corneal-compensated intraocular pressure. However, lens thickness and vitreous length measurements were not affected by contact lens use, and ACD measurements from different devices were not interchangeable.