☆ 4.3 Review

Selective efferent vagal stimulation in heart failure

EXPERIMENTAL PHYSIOLOGY (2023)

Related references

Note: Only part of the references are listed.

Article Clinical Neurology

Organ- and function-specific anatomical organization of vagal fibers supports fascicular vagus nerve stimulation

Naveen Jayaprakash et al.

Summary: Through studying pigs, we found that the fibers inside the vagus nerve are anatomically organized according to their mediated functions and innervated organs, and can be selectively activated by cervical nerve stimulation. These results indicate that the fibers in the vagus nerve trunk are anatomically organized based on the functions they mediate and organs they innervate, and can be selectively activated by specific electrical stimulation.

BRAIN STIMULATION (2023)

Add to Collection

Article Neurosciences

Organotopic organization of the porcine mid-cervical vagus nerve

Nicole Thompson et al.

Summary: The study found localized fascicles in the porcine cervical vagus nerve that map to cardiac, pulmonary, and recurrent laryngeal function, which could lead to improved outcomes in vagus nerve stimulation for various disorders.

FRONTIERS IN NEUROSCIENCE (2023)

Add to Collection

Article Multidisciplinary Sciences

Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the alpha 7nAChR subunit

April S. Caravaca et al.

Summary: Stimulating the vagus nerve accelerates the resolution of inflammation in mice by increasing levels of SPM and shifting the balance between proinflammatory and proresolving lipid mediators. This process requires the enzyme Alox15 and the alpha 7nAChR receptor component of the inflammatory reflex.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)

Add to Collection

Article Physiology

Structure and Functions of the Vagus Nerve in Mammals

Matteo M. Ottayiani et al.

Summary: This article reviews the structure, function, and role of the vagus nerve in the autonomic nervous system. The vagus nerve is the largest and longest cranial nerve, primarily functioning as a sensory nerve with extensive distribution across multiple organ systems. The article provides detailed descriptions of the macroscopic and microscopic features of the nerve, as well as the central nuclei and histochemical/genetic profiles associated with sensory information processing. Furthermore, it comprehensively discusses the physiological roles of the vagus nerve in cardiovascular, respiratory, and gastrointestinal control, as well as its interactions with the immune system.

COMPREHENSIVE PHYSIOLOGY (2022)

Add to Collection

Article Clinical Neurology

Selective optogenetic stimulation of efferent fi bers in the vagus nerve of a large mammal

Lindsea C. Booth et al.

Summary: This study successfully applied optogenetics for selective stimulation of vagal efferent activity in a large animal model (sheep). Viral transduction of a subset of vagal motoneurons resulted in strong axonal membrane expression of the excitatory light-sensitive ion channel ChIEF in efferent projections innervating thoracic organs and reaching beyond the diaphragm.

BRAIN STIMULATION (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Vagal stimulation in heart failure

Veronica Dusi et al.

Summary: Vagal nerve stimulation (VNS) has theoretical potential for heart failure treatment, but previous large trials failed to demonstrate expected benefits. More understanding of the complex dose-response issue of VNS has been gathered and a new randomized study with a refined approach is currently underway to deliver proper doses to a more selected group of patients.

HERZ (2021)

Add to Collection

Article Biochemical Research Methods

Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation

Kirill Aristovich et al.

Summary: Optimized electrical neuromodulation of the cervical vagus nerve can selectively affect respiratory rate or heart rate, revealing organ-specific organization of neural fibers in the cervical vagus nerve.

JOURNAL OF NEUROSCIENCE METHODS (2021)

Add to Collection

Review Anatomy & Morphology

The anatomical basis for transcutaneous auricular vagus nerve stimulation

Mohsin F. Butt et al.

JOURNAL OF ANATOMY (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Optogenetic Control of Airway Cholinergic Neurons In Vivo

Alexandra B. Pincus et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)

Add to Collection

Article Engineering, Biomedical

Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation

Megan L. Settell et al.

JOURNAL OF NEURAL ENGINEERING (2020)

Add to Collection

Review Cardiac & Cardiovascular Systems

Inflammatory Cytokines and Chemokines as Therapeutic Targets in Heart Failure

Anis Hanna et al.

CARDIOVASCULAR DRUGS AND THERAPY (2020)

Add to Collection

Article Cardiac & Cardiovascular Systems

Optogenetic Stimulation of Vagal Efferent Activity Preserves Left Ventricular Function in Experimental Heart Failure

Asif Machhada et al.

JACC-BASIC TO TRANSLATIONAL SCIENCE (2020)

Add to Collection

Article Multidisciplinary Sciences

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

Pradeep S. Rajendran et al.

NATURE COMMUNICATIONS (2019)

Add to Collection

Review Cardiac & Cardiovascular Systems

G protein-coupled receptor kinases as therapeutic targets in the heart

Jessica Pfleger et al.

NATURE REVIEWS CARDIOLOGY (2019)

Add to Collection

Review Cardiac & Cardiovascular Systems

The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies

Neil Herring et al.

NATURE REVIEWS CARDIOLOGY (2019)

Add to Collection

Article Immunology

Vagal afferent activation suppresses systemic inflammation via the splanchnic anti-inflammatory pathway

Evilin Naname Komegae et al.

BRAIN BEHAVIOR AND IMMUNITY (2018)

Add to Collection

Article Cardiac & Cardiovascular Systems

The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

Marc van Bilsen et al.

EUROPEAN JOURNAL OF HEART FAILURE (2017)

Add to Collection

Article Engineering, Biomedical

Transdermal optogenetic peripheral nerve stimulation

Benjamin E. Maimon et al.

JOURNAL OF NEURAL ENGINEERING (2017)

Add to Collection

Article Multidisciplinary Sciences

Vagal determinants of exercise capacity

Asif Machhada et al.

NATURE COMMUNICATIONS (2017)

Add to Collection

Article Cardiac & Cardiovascular Systems

Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning

Marina V. Basalay et al.

CARDIOVASCULAR RESEARCH (2016)

Add to Collection

Article Neurosciences

Origins of the vagal drive controlling left ventricular contractility

Asif Machhada et al.

JOURNAL OF PHYSIOLOGY-LONDON (2016)

Add to Collection

Article Cardiac & Cardiovascular Systems

Vagus Nerve Stimulation for the Treatment of Heart Failure The INOVATE-HF Trial

Michael R. Gold et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Add to Collection

Article Cardiac & Cardiovascular Systems

Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve

Asif Machhada et al.

HEART RHYTHM (2015)

Add to Collection

Article Physiology

Afferent vagal nerve stimulation resets baroreflex neural arc and inhibits sympathetic nerve activity

Keita Saku et al.

PHYSIOLOGICAL REPORTS (2014)

Add to Collection

Article Cardiac & Cardiovascular Systems

Vagus nerve stimulation improves left ventricular function in a canine model of chronic heart failure

Jason J. Hamann et al.

EUROPEAN JOURNAL OF HEART FAILURE (2013)

Add to Collection

Review Chemistry, Multidisciplinary

β-Adrenergic receptor subtype signaling in heart: From bench to bedside

Anthony Yiu Ho Woo et al.

ACTA PHARMACOLOGICA SINICA (2012)

Add to Collection

Article Cardiac & Cardiovascular Systems

Vagus nerve stimulation protects against ventricular fibrillation independent of muscarinic receptor activation

Kieran E. Brack et al.

CARDIOVASCULAR RESEARCH (2011)

Add to Collection

Article Medicine, General & Internal

National and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008

Jersey Chen et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)

Add to Collection

Article Cardiac & Cardiovascular Systems

Long term vagal stimulation in patients with advanced heart failure First experience in man

Peter J. Schwartz et al.

EUROPEAN JOURNAL OF HEART FAILURE (2008)

Add to Collection

Article Cardiac & Cardiovascular Systems

Modulation of the myocardial redox state by vagal nerve stimulation after experimental myocardial infarction

Takaki Tsutsumi et al.

CARDIOVASCULAR RESEARCH (2008)

Add to Collection

Article Cardiac & Cardiovascular Systems

Increased cardiac sympathetic nerve activity in heart failure is not due to desensitization of the arterial baroreflex

A. M. D. Watson et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)

Add to Collection

Article Cardiac & Cardiovascular Systems

Vagal nerve stimulation markedly improves long-term survival after chronic heart failure in rats

M Li et al.

CIRCULATION (2004)

Add to Collection

Article Medicine, General & Internal

Long-term trends in the incidence of and survival with heart failure

D Levy et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)

Add to Collection

© Peeref 2019-2024. All rights reserved.