Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 58, Pages 11630-11633Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc03902a
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Categories
Funding
- 973 Project [2011CB936004, 2012CB720602]
- NSFC [21210002, 21431007, 91413111]
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Herein we report a convenient and sensitive method for the detection of telomerase activity based on upconversion nanoparticle (UCNP) modified cellulose paper. Compared with many solution-phase systems, this paper chip is more stable and easily stores the test results. What's more, the low background fluorescence of the UCNPs increases the sensitivity of this method, and the low telomerase levels in different cell lines can clearly be discriminated by the naked eye.
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