4.5 Article

Development of the Meyer-Schuster Rearrangement on Propargylic Alcohols with Fluorinated Chains

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Summary: The Meyer-Schuster rearrangement is an efficient method for preparing alpha,beta-unsaturated carbonyl compounds from propargylic alcohols, with significant progress made in the past decade. New catalytic systems and elegant applications have been discovered, including cascade processes and total synthesis of complex natural products. Additionally, the first examples of aza-Meyer-Schuster rearrangements have recently been described.

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