Journal
MEMORIAS DO INSTITUTO OSWALDO CRUZ
Volume 111, Issue 1, Pages 79-81Publisher
FUNDACO OSWALDO CRUZ
DOI: 10.1590/0074-02760150350
Keywords
Onchocerca volvulus mitochondria; onchocerciasis; Brazilian Amazonia focus; mitogenome
Categories
Funding
- FAPEAM
- BSM/CAPES
- PNPD/CAPES
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We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa. An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of high-throughput and Sanger sequencing technologies. Comparisons made between this mitochondrial genome and publicly available mitochondrial sequences identified 46 variant nucleotide positions and suggested that our Brazilian mitogenome is more closely related to Cameroon-origin mitochondria than West African-origin mitochondria. As well as providing insights into the origins of Latin American onchocerciasis, the Brazilian Amazonia focus mitogenome may also have value as an epidemiological resource.
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