Related references
Note: Only part of the references are listed.The M-CSF receptor in osteoclasts and beyond
Se Hwan Mun et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
Optimization of an azetidine series as inhibitors of colony stimulating factor-1 receptor (CSF-1R) Type II to lead to the clinical candidate JTE-952
Kazutaka Ikegashira et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)
Colony-stimulating factor 1 receptor inhibition prevents against lipopolysaccharide -induced osteoporosis by inhibiting osteoclast formation
Xin-fang Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Emerging Roles for Eph Receptors and Ephrin Ligands in Immunity
Thayer K. Darling et al.
FRONTIERS IN IMMUNOLOGY (2019)
Role of purines in regulation of metabolic reprogramming
Zhenwei Tang et al.
PURINERGIC SIGNALLING (2019)
What Makes a Kinase Promiscuous for Inhibitors?
Sonya M. Hanson et al.
CELL CHEMICAL BIOLOGY (2019)
Recent advances in colony stimulating factor-1 receptor/c-FMS as an emerging target for various therapeutic implications
Archana Kumari et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Recent Advances of Colony-Stimulating Factor-1 Receptor (CSF-1R) Kinase and Its Inhibitors
Mohammed El-Gamal et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours
Behzad M. Toosi et al.
ONCOGENE (2018)
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
Michael A. Cannarile et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment
Amr El Zawily et al.
SCIENTIFIC REPORTS (2017)
Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors
Sreekanth A. Ramachandran et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Design strategies, structure activity relationship insights for purines as kinase inhibitors
Sahil Sharma et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids
George Hedger et al.
SCIENTIFIC REPORTS (2015)
Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d] pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity
Svein Jacob Kaspersen et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor
Chao Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The osteoclast, bone remodelling and treatment of metabolic bone disease
Brendan F. Boyce et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2012)
Methyl Effects on Protein-Ligand Binding
Cheryl S. Leung et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
A Novel Mode of Protein Kinase Inhibition Exploiting Hydrophobic Motifs of Autoinhibited Kinases DISCOVERY OF ATP-INDEPENDENT INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR
Sudharshan Eathiraj et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Understanding the Impact of the P-loop Conformation on Kinase Selectivity
Cristiano R. W. Guimaraes et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
Regioselective Sonogashira cross-coupling reactions of 6-chloro-2,8-diiodo-9-THP-9H-purine with alkyne derivatives
Nada Ibrahim et al.
TETRAHEDRON LETTERS (2011)
Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-α: Hit to lead studies
Adam M. Gilbert et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Activation State-Dependent Binding of Small Molecule Kinase Inhibitors: Structural Insights from Biochemistry
Lisa M. Wodicka et al.
CHEMISTRY & BIOLOGY (2010)
Novel 8-arylated purines as inhibitors of glycogen synthase kinase
Nada Ibrahim et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
9-(Arenethenyl)purines as Dual Src/Abl Kinase Inhibitors Targeting the Inactive Conformation: Design, Synthesis, and Biological Evaluation
Wei-Sheng Huang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Energetics of Displacing Water Molecules from Protein Binding Sites: Consequences for Ligand Optimization
Julien Michel et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors
Carsten Schubert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Ligand efficiency indices for effective drug discovery
Cele Abad-Zapatero
EXPERT OPINION ON DRUG DISCOVERY (2007)
Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580
JG Conway et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Glide: A new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening
TA Halgren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Juxtamembrane autoinhibition in receptor tyrosine kinases
SR Hubbard
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
The chemodiversity of purine as a constituent of natural products
H Rosemeyer
CHEMISTRY & BIODIVERSITY (2004)
Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain
P Saharinen et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
A comparison of physiochemical property profiles of development and marketed oral drugs
MC Wenlock et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)