Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 8, Pages 1475-1478Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc08831j
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Funding
- National Natural Science Foundation of China [51125014, 51233003, 51303137]
- Ministry of Science and Technology of China [2011CB606202]
- Ministry of Education of China [20120141130003]
- Natural Science Foundation of Hubei Province of China [2013CFA003]
- Chinese Postdoctoral Science Foundation [2012M521459, 2013M540598]
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A dual stimuli-responsive multi-drug delivery system was developed for cancer cocktail therapy. Upon UV irradiation, microcapsules could rapidly release the small-molecule drugs, and thereafter the macromolecular drugs would be released in the presence of MMP in the tumor cells. This system will find great potential as a novel chemotherapeutic combination for cancer treatment.
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