☆ 4.8 Article

Chronic Pb Exposure Induces Anxiety and Depression-like Behaviors in Mice via Excitatory Neuronal Hyperexcitability in Ventral Hippocampal Dentate Gyrus

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2023)

Related references

Note: Only part of the references are listed.

Article Neurosciences

Early-life low-level lead exposure alters anxiety-like behavior, voluntary alcohol consumption and AC5 protein content in adult male and female C57BL/6 J mice

Maribel Hernandez et al.

Summary: Despite efforts to eliminate sources of environmental lead, children are still exposed to unsafe levels of lead from soil, dust, and water. This study investigates the effects of early-life lead exposure on alcohol consumption and anxiety-like behavior in mice. The results show that mice with early-life lead exposure consumed more alcohol and exhibited greater anxiety-like behavior. It was also found that lead exposure increased the protein content of Adenylate Cyclase-5 (AC5) in the whole brain but not in specific regions. These findings highlight the importance of understanding the mechanisms behind lead exposure and its impact on alcohol intake.

NEUROTOXICOLOGY AND TERATOLOGY (2023)

Add to Collection

Article Multidisciplinary Sciences

Lead content in automotive paints purchased at formal and informal outlets in Kenya

Lilian Mwai et al.

Summary: This study aimed to assess the lead (Pb) levels in automotive paints frequently used by informal spray painters. The results showed that all the paints from informal retail shops exceeded the regulatory limit of 90 ppm, with the blue paint having levels 30 times higher than the set limit. In contrast, paints from formal stores had significantly lower Pb levels than those from informal stores. Overall, high Pb levels in automotive paints used in unregulated environments could be potential sources of exposure and environmental contamination, calling for enforcement of regulatory limits and comprehensive Pb exposure assessments.

HELIYON (2023)

Add to Collection

Article Environmental Sciences

Sediment quality and environmental risk assessment in a Mediterranean coastal system using geochemical and multivariate statistical analyses: the case of Boughrara Lagoon (southeastern Tunisia)

Nejia Tlig et al.

Summary: Our study determined the spatial variability of chemical element concentrations and their sources in the surficial sediments of the Boughrara Lagoon in southeastern Tunisia. The lagoon was found to be highly polluted, especially with regards to Cd, Pb, and Fe, and three potential sources of pollution were identified. Additionally, the presence of pyrite precipitation suggests the occurrence of anoxic conditions in the lagoon.

ENVIRONMENTAL MONITORING AND ASSESSMENT (2023)

Add to Collection

Article Plant Sciences

Clerodendrum viscosum leaves attenuate lead-induced neurotoxicity through upregulation of BDNF-Akt-Nrf2 pathway in mice

Jahidul Islam et al.

Summary: This study aimed to evaluate the protective effect of aqueous extract of C. viscosum leaves against lead-induced neurobehavioral and biochemical changes in mice. The results showed that C. viscosum leaves restored cognitive dysfunction and reduced anxiety-like behavior through upregulation of BDNF mediated Akt-Nrf2 pathway in lead-exposed mice.

JOURNAL OF ETHNOPHARMACOLOGY (2023)

Add to Collection

Article Environmental Sciences

An assessment of the relation between metal contaminated sediment and freshwater mussel populations in the Big River, Missouri

Andrew D. Roberts et al.

Summary: This article investigates the impacts of lead contamination on freshwater mussel populations in the Big River in southeast Missouri. The study finds that lead-contaminated sediments significantly decrease mussel abundance and are negatively correlated with lead concentrations. The results suggest that lead toxicity is likely the cause of the decline in mussel populations within the Big River.

SCIENCE OF THE TOTAL ENVIRONMENT (2023)

Add to Collection

Article Biochemistry & Molecular Biology

Neuroprotective Effects of Shogaol in Metals (Al, As and Pb) and High-fat diet-induced Neuroinflammation and Behavior in Mice

Sara Ishaq et al.

Summary: This study aimed to evaluate the protective effects of Shogaol (an active component of ginger) in neuroinflammation and behavioral paradigms in mice treated with toxic metals and high-fat diet. The results showed that Shogaol treatment improved metabolic profile, reduced expression of neuroinflammatory genes, and enhanced blood-brain barrier integrity. Behavioral analysis demonstrated that Shogaol treatment rescued behavioral impairments and improved anxiety and depression. Therefore, Shogaol has strong therapeutic potential and can be considered as a potential drug candidate in the future.

CURRENT MOLECULAR PHARMACOLOGY (2023)

Add to Collection

Article Neurosciences

Alcohol Dependence Modifies Brain Networks Activated During Withdrawal and Reaccess: A c-Fos-Based Analysis in Mice

Alison V. Roland et al.

Summary: High-level alcohol consumption leads to neuroplastic changes in the brain that promote pathological drinking behavior. In a study using a well-characterized model of alcohol dependence, researchers found that alcohol withdrawal causes changes in brain network organization that are attenuated by reaccess drinking. Olfactory brain regions, particularly the cortical amygdala, play an important role in alcohol dependence.

BIOLOGICAL PSYCHIATRY (2023)

Add to Collection

Article Psychology, Developmental

Trajectories of Screen Time across Adolescence and Their Associations with Adulthood Mental Health and Behavioral Outcomes

Xinxin Zhu et al.

Summary: Excessive screen time among adolescents is a significant public health concern. This study identified five different patterns of screen use during adolescence and found that these patterns were associated with mental health and behavioral issues in early adulthood. The results highlight the importance of addressing problematic screen usage patterns to improve outcomes in these domains.

JOURNAL OF YOUTH AND ADOLESCENCE (2023)

Add to Collection

Article Environmental Sciences

Health risks of heavy metals in food and their economic burden in Armenia

Davit Pipoyan et al.

Summary: Mining in Armenia leads to excessive heavy metal contamination of agricultural products, which poses adverse health effects. This study measures the concentrations of toxic heavy metals in food samples from local markets and combines them with data from a diet survey to estimate people's daily intake. The findings show that lead exposure from food is a safety concern, with over 50% of the population exceeding the benchmark dose level set by the European Food Safety Authority. Additionally, the study reveals that lead exposure has the potential to increase blood pressure, lower IQ levels, and reduce lifetime earnings.

ENVIRONMENT INTERNATIONAL (2023)

Add to Collection

Article Clinical Neurology

Association between subclinical hypothyroidism and psychotic features in Chinese young adults with first-episode and untreated major depressive disorder

Wenyu Dai et al.

Summary: In young patients with first-episode and untreated MDD, subclinical hypothyroidism (SCH) and thyroid antibody positivity were found to be common. MDD patients with SCH are more likely to experience psychotic symptoms, and TSH levels may be a risk factor for these symptoms and disease severity.

JOURNAL OF AFFECTIVE DISORDERS (2023)

Add to Collection

Article Medicine, Research & Experimental

Elevated prelimbic cortex-to-basolateral amygdala circuit activity mediates comorbid anxiety-like behaviors associated with chronic pain

Feng Gao et al.

Summary: Chronic pain can lead to hyperalgesia and anxiety symptoms. This study reveals that neurons in the prelimbic cortex (PrL), which project to the basolateral amygdala (PrLBLA) and the ventrolateral periaqueductal gray (PrLl/vlPAG), exhibit increased and decreased activity, respectively, during chronic pain. Optogenetic manipulation shows that suppressing the PrL-BLA circuit reverses anxiety-like behaviors, while activating the PrL-l/vlPAG circuit reduces hyperalgesia in mice with chronic pain. Mechanistic studies suggest that elevated TNF-alpha/TNFR1 signaling in the PrL leads to increased insertion of GluA1 receptors into PrLBLA neurons and contributes to anxiety-like behaviors.

JOURNAL OF CLINICAL INVESTIGATION (2023)

Add to Collection

Article Engineering, Environmental

Toxicity Assessment of 91-Day Repeated Inhalation Exposure to an Indoor School Air Mixture of PCBs

Hui Wang et al.

Summary: Indoor air in schools contaminated with PCBs may pose health risks to children, teachers, and staff. Our study found that long-term inhalation exposure to PCBs impaired memory, induced anxiety-like behavior, reduced white blood cell counts, and influenced metabolism and gene transcription.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Parental Lead Exposure Promotes Neurobehavioral Disorders and Hepatic Dysfunction in Mouse Offspring

Hasan Ul Banna et al.

Summary: The study found that continuous exposure to lead from fetus to adult results in more severe impacts on neurobehavioral changes and liver toxicity, including increased anxiety-like behavior, memory and learning impairments, lower BChE activity, higher lead levels in the brain, elevated serum hepatic enzyme activities, and more pronounced hepatic tissue injury compared to adult exposure only.

BIOLOGICAL TRACE ELEMENT RESEARCH (2022)

Add to Collection

Article Engineering, Environmental

Airborne lead: A vital factor influencing rice lead accumulation in China

Qi Lin et al.

Summary: The study reveals the significant impact of aerosol lead on lead content in rice grains in China, highlighting the strong influence of long-range lead transport on agricultural environment. The research findings suggest that the accumulation ratio of lead in rice grains is related to grain weight and accumulation types.

JOURNAL OF HAZARDOUS MATERIALS (2022)

Add to Collection

Article Engineering, Environmental

New Insights into Prenatal NO2 Exposure and Behavioral Abnormalities in Male Offspring: Disturbed Serotonin Metabolism and Delayed Oligodendrocyte Development

Dan Li et al.

Summary: This study provides experimental evidence that prenatal exposure to nitrogen dioxide (NO2) causes anxiety and depression-like behaviors in male offspring. The behavioral abnormalities are associated with delayed oligodendrocyte (OL) development and abnormal myelination. The disturbed metabolism of placental neurotransmitters, specifically serotonin (5-HT), plays a role in the development of these behavioral abnormalities.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2022)

Add to Collection

Article Neurosciences

Low-level lead exposure during development differentially affects neurobehavioral responses in male and female mouse offspring: A longitudinal study

Oykue Dinckol et al.

Summary: Early life low-level lead exposure has significant effects on child health. However, there is a lack of animal studies investigating the effects of low doses of lead from early stages of life to adulthood. In this study using a mouse model, developmental exposure to low-level lead caused mild alterations in motor and social behavior, and more severe impairments in spatial learning and memory in males. Additionally, lead levels were elevated in blood, brain, and bone for up to six months after exposure. These findings emphasize the importance of animal models in understanding the impact of early chronic low-level lead exposure on health.

NEUROTOXICOLOGY (2022)

Add to Collection

Article Environmental Sciences

Lead in Air, Soil, and Blood: Pb Poisoning in a Changing World

Howard W. Mielke et al.

Summary: The dust from leaded petrol continues to pose major exposure risks to humans, which require reducing the exposure to lead in soil and curtailing the remobilization of soil lead into the atmosphere.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Add to Collection

Article Psychiatry

Striatal Activity to Reward Anticipation as a Moderator of the Association Between Early Behavioral Inhibition and Changes in Anxiety and Depressive Symptoms From Adolescence to Adulthood

Alva Tang et al.

Summary: The early childhood temperament of behavioral inhibition (BI) is associated with increased risk for anxiety and depression. This study explores the neurocognitive correlates underlying vulnerability to the development of depression and finds that reduced activity in the nucleus accumbens moderates the association between early BI and increases in depressive symptoms. Future research should focus on prevention programs targeting maladaptive reward processing and motivational deficits among anxious youths to reduce the risk of later depression.

JAMA PSYCHIATRY (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Interferon and anti-TNF therapies differentially modulate amygdala reactivity which predicts associated bidirectional changes in depressive symptoms

Kevin A. Davies et al.

Summary: Patients receiving IFN-α treatment for Hepatitis-C showed significant increase in depressive symptoms at 4 weeks, whereas those receiving anti-TNF therapy for inflammatory arthritis exhibited marked improvement in depressive symptoms at 24 hours and 12 weeks. The study found that both IFN-α and anti-TNF significantly modulated amygdala reactivity, with IFN-α enhancing right amygdala responses to sad faces and anti-TNF decreasing right amygdala reactivity.

MOLECULAR PSYCHIATRY (2021)

Add to Collection

Article Biochemistry & Molecular Biology

P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness

Vasco C. Sousa et al.

Summary: Patients with mood disorders and anxiety often show hyperresponsiveness in the hypothalamic-pituitary-adrenocortical (HPA) axis and autonomic nervous system. It has been found that p11 deficiency is associated with depression-like phenotypes. In this study, p11-deficient mice were used to investigate the role of p11 in stress responsiveness, showing increased response to stress in p11KO mice, along with hyperactivity in the HPA and SAM axes. These findings suggest that p11 deficiency may lead to increased stress reactivity and behavioral changes related to depression and anxiety.

MOLECULAR PSYCHIATRY (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Lead (Pb) exposure induces physiological alterations in the serotoninergic and vasopressin systems causing anxiogenic-like behavior in Meriones shawi: Assessment of BDMC as a neuroprotective compound for Pb-neurotoxicity and kidney damages

Lahcen Tamegart et al.

Summary: The study discovered that lead exposure could cause anxiety and disruptions in the nervous system, but BDMC can act as a neuroprotective agent by restoring serotonin and vasopressin function, alleviating anxiety symptoms; in addition, BDMC can also mitigate renal damages induced by lead exposure.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2021)

Add to Collection

Review Environmental Sciences

Cognitive Impairment Induced by Lead Exposure during Lifespan: Mechanisms of Lead Neurotoxicity

Daniela Ramirez Ortega et al.

Summary: Lead (Pb) is considered a strong environmental toxin with detrimental effects on human health, particularly on the central nervous system. Exposure to Pb can lead to cognitive impairment, abnormal social behavior, and other adverse effects. Early life exposure to Pb may result in more severe consequences.

TOXICS (2021)

Add to Collection

Article Engineering, Environmental

Lead (Pb) concentrations and speciation in residential soils from an urban community impacted by multiple legacy sources

Ezazul Haque et al.

Summary: Elevated soil lead concentrations in East Chicago were widespread and above regulatory limits, with levels increasing in neighborhoods with lower median household income. The soil lead was primarily adsorbed to iron and manganese oxides or humic acids, regardless of contamination levels. The lack of detectable crystalline insoluble forms of lead suggests that potential sources such as paint, ore, and slag are repartitioned into more bioavailable forms in the soil. These findings have implications for remediation efforts and human health due to significantly elevated blood lead levels in the community.

JOURNAL OF HAZARDOUS MATERIALS (2021)

Add to Collection

Review Public, Environmental & Occupational Health

Lead (Pb) and neurodevelopment: A review on exposure and biomarkers of effect (BDNF, HDL) and susceptibility

Claudia Gundacker et al.

Summary: Lead (Pb) is a common environmental pollutant with potent toxic effects on human health. Effective biomarkers are needed to assess the relationship between Pb exposure and health outcomes, especially in situations of low to moderate exposure. Further studies are required to validate sensitive and reliable biomarkers for Pb-induced toxicity.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2021)

Add to Collection

Article Toxicology

Pb exposure induces an imbalance of excitatory and inhibitory synaptic transmission in cultured rat hippocampal neurons

Rong-Xin Zou et al.

TOXICOLOGY IN VITRO (2020)

Add to Collection

Article Multidisciplinary Sciences

Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect

Guilin Pi et al.

NATURE COMMUNICATIONS (2020)

Add to Collection

Article Endocrinology & Metabolism

Dysfunction of serotonergic activity and emotional responses across the light-dark cycle in mice lacking melatonin MT2 receptors

Stefano Comai et al.

JOURNAL OF PINEAL RESEARCH (2020)

Add to Collection

Review Psychology, Clinical

Humanistic and economic burden of depression and anxiety among adults with migraine: A systematic review

Monira Alwhaibi et al.

DEPRESSION AND ANXIETY (2020)

Add to Collection

Review Biochemistry & Molecular Biology

(Ascorb)ing Pb Neurotoxicity in the Developing Brain

Faraz Ahmad et al.

ANTIOXIDANTS (2020)

Add to Collection

Article Neurosciences

Perineuronal Nets, Inhibitory Interneurons, and Anxiety-Related Ventral Hippocampal Neuronal Oscillations Are Altered by Early Life Adversity

Sahana Murthy et al.

BIOLOGICAL PSYCHIATRY (2019)

Add to Collection

Article Behavioral Sciences

Long-term consequences of early postnatal lead exposure on hippocampal synaptic activity in adult mice

Anahis Tena et al.

BRAIN AND BEHAVIOR (2019)

Add to Collection

Article Psychiatry

Augmentation effect of ketamine by guanosine in the novelty-suppressed feeding test is dependent on mTOR signaling pathway

Anderson Camargo et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2019)

Add to Collection

Article Cell Biology

Interplay of miR-137 and EZH2 contributes to the genome-wide redistribution of H3K27me3 underlying the Pb-induced memory impairment

Xiaozhen Gu et al.

CELL DEATH & DISEASE (2019)

Add to Collection

Article Biochemistry & Molecular Biology

JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche

H. Mohammad et al.

MOLECULAR PSYCHIATRY (2018)

Add to Collection

Article Biochemistry & Molecular Biology

Protein kinase Mζ in medial prefrontal cortex mediates depressive-like behavior and antidepressant response

W. Yan et al.

MOLECULAR PSYCHIATRY (2018)

Add to Collection

Article Neurosciences

Anxiety Cells in a Hippocampal-Hypothalamic Circuit

Jessica C. Jimenez et al.

NEURON (2018)

Add to Collection

Article Neurosciences

Developmental manganese, lead, and barren cage exposure have adverse long-term neurocognitive, behavioral and monoamine effects in Sprague-Dawley rats

Jenna L. N. Sprowles et al.

NEUROTOXICOLOGY AND TERATOLOGY (2018)

Add to Collection

Article Toxicology

Effect of Pb Exposure on Synaptic Scaling Through Regulation of AMPA Receptor Surface Trafficking

Jin-Jun Ding et al.

TOXICOLOGICAL SCIENCES (2018)

Add to Collection

Article Environmental Sciences

Dentine biomarkers of prenatal and early childhood exposure to manganese, zinc and lead and childhood behavior

Megan K. Horton et al.

ENVIRONMENT INTERNATIONAL (2018)

Add to Collection

Article Multidisciplinary Sciences

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

Christoph Anacker et al.

NATURE (2018)

Add to Collection

Article Neurosciences

Intermittent low-level lead exposure provokes anxiety, hypertension, autonomic dysfunction and neuroinflammation

Liana Shvachiy et al.

NEUROTOXICOLOGY (2018)

Add to Collection

Article Toxicology

Pb inhibits hippocampal synaptic transmission via cyclin-dependent kinase-5 dependent Synapsin 1 phosphorylation

Jin-Jun Ding et al.

TOXICOLOGY LETTERS (2018)

Add to Collection

Article Pediatrics

Effect of Residential Lead-Hazard Interventions on Childhood Blood Lead Concentrations and Neurobehavioral Outcomes A Randomized Clinical Trial

Joseph M. Braun et al.

JAMA PEDIATRICS (2018)

Add to Collection

Article Multidisciplinary Sciences

Integrative bioinformatics identifies postnatal lead (Pb) exposure disrupts developmental cortical plasticity

Milo R. Smith et al.

SCIENTIFIC REPORTS (2018)

Add to Collection

Article Public, Environmental & Occupational Health

Three cycles of human biomonitoring in Flanders - Time trends observed in the Flemish Environment and Health Study

Greet Schoeters et al.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2017)

Add to Collection

Review Neurosciences

Adult hippocampal neurogenesis and cognitive flexibility - linking memory and mood

Christoph Anacker et al.

NATURE REVIEWS NEUROSCIENCE (2017)

Add to Collection

Article Neurosciences

Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress

Carla Nasca et al.

NEURON (2017)

Add to Collection

Review Neurosciences

The Neurobiology of Postpartum Anxiety and Depression

Jodi L. Pawluski et al.

TRENDS IN NEUROSCIENCES (2017)

Add to Collection

Article Cell Biology

Structure-based assessment of disease-related mutations in human voltage-gated sodium channels

Weiyun Huang et al.

PROTEIN & CELL (2017)

Add to Collection

Article Neurosciences

Lead Exposure Impairs Hippocampus Related Learning and Memory by Altering Synaptic Plasticity and Morphology During Juvenile Period

Tao Wang et al.

MOLECULAR NEUROBIOLOGY (2016)

Add to Collection

Article Biochemistry & Molecular Biology

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism

P. Zheng et al.

MOLECULAR PSYCHIATRY (2016)

Add to Collection

Review Chemistry, Medicinal

Selective Blocking Effects of 4,9-Anhydrotetrodotoxin, Purified from a Crude Mixture of Tetrodotoxin Analogues, on NaV1.6 Channels and Its Chemical Aspects

Noriyoshi Teramoto et al.

MARINE DRUGS (2015)

Add to Collection

Article Psychology, Biological

Effect of pentobarbital and isoflurane on acute stress response in rat

Xue-Yan Wu et al.

PHYSIOLOGY & BEHAVIOR (2015)

Add to Collection

Article Multidisciplinary Sciences

The Forced Swim Test as a Model of Depressive-like Behavior

Roni Yankelevitch-Yahav et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2015)

Add to Collection

Article Geriatrics & Gerontology

Behavioral testing-related changes in the expression of Synapsin I and glucocorticoid receptors in standard and enriched aged Wistar rats

P. Sampedro-Piquero et al.

EXPERIMENTAL GERONTOLOGY (2014)

Add to Collection

Article Psychology, Biological

Lead-induced effects on learning/memory and fear/anxiety are correlated with disturbances in specific cholinesterase isoform activity and redox imbalance in adult brain

Anastasia-Varvara Ferlemi et al.

PHYSIOLOGY & BEHAVIOR (2014)

Add to Collection

Article Psychology

From Stress to Inflammation and Major Depressive Disorder: A Social Signal Transduction Theory of Depression

George M. Slavich et al.

PSYCHOLOGICAL BULLETIN (2014)

Add to Collection

Review Biotechnology & Applied Microbiology

Pb Neurotoxicity: Neuropsychological Effects of Lead Toxicity

Lisa H. Mason et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Add to Collection

Article Pediatrics

Blood Lead Concentrations and Children's Behavioral and Emotional Problems A Cohort Study

Jianghong Liu et al.

JAMA PEDIATRICS (2014)

Add to Collection

Article Behavioral Sciences

Use of the light/dark test for anxiety in adult and adolescent male rats

Andrew E. Arrant et al.

BEHAVIOURAL BRAIN RESEARCH (2013)

Add to Collection

Article Biochemistry & Molecular Biology

Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects

Martha } Pedraza Escalona et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2013)

Add to Collection

Article Neurosciences

Serotonergic and Noradrenergic Pathways Are Required for the Anxiolytic-like and Antidepressant-like Behavioral Effects of Repeated Vagal Nerve Stimulation in Rats

Havan Furmaga et al.

BIOLOGICAL PSYCHIATRY (2011)

Add to Collection

Article Pharmacology & Pharmacy

Alterations in glucocorticoid negative feedback following maternal Pb, prenatal stress and the combination: A potential biological unifying mechanism for their corresponding disease profiles

A. Rossi-George et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2009)

Add to Collection

Article Multidisciplinary Sciences

Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice

Daniel Huber et al.

NATURE (2008)

Add to Collection

Article Multidisciplinary Sciences

Behavioural report of single neuron stimulation in somatosensory cortex

Arthur R. Houweling et al.

NATURE (2008)

Add to Collection

Article Pharmacology & Pharmacy

New and evolving concepts in the neurotoxicology of lead

L. D. White et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)

Add to Collection

Review Neurosciences

A computational theory of hippocampal function, and empirical tests of the theory

Edmund T. Rolls et al.

PROGRESS IN NEUROBIOLOGY (2006)

Add to Collection

Article Environmental Sciences

Low-level environmental lead exposure and children's intellectual function: An international pooled analysis

BP Lanphear et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2005)

Add to Collection

Article Neurosciences

Effects of lead on voltage-gated sodium channels in rat hippocampal CA1 neurons

Y Gu et al.

NEUROSCIENCE (2005)

Add to Collection

Article Neurosciences

Lower in vivo brain extracellular GABA concentration in diabetic rats during forced swimming

R Gomez et al.

BRAIN RESEARCH (2003)

Add to Collection

© Peeref 2019-2024. All rights reserved.