Simultaneous determination of ascorbic acid, dopamine, and uric acid with a highly selective and sensitive reduced graphene oxide/polypyrrole-platinum nanocomposite modified electrochemical sensor

In this article, a new method for the synthesis of reduced graphene oxide/polypyrrole-platinum (rGO/PPy-Pt) nanoparticles via microwave-assisted procedure is reported. Material characterization of the synthesized nanocomposites was carried out with X-Ray Diffraction Diffractometry (XRD), Scanning Electron Microscope (SEM), and Fourier Transform Infrared Spectrophotometer (FTIR). In addition, the electrocatalytic performance of rGO/PPy-Pt nanocomposites for the determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA) was carried out by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) measurements. Under optimized conditions, linear calibration plots were found to be 0.8-2.1 mM, 0.03 - 1.4 mM, and 0.1-0.35 mM with corresponding detection limits of 0.12 mu M, 0.071 mu M, and 0.16 mu M for AA, DA, and UA, respectively. In the results obtained, it was seen that the rGO/PPy-Pt bimetallic composite provided high electrocatalytic performance against AA, DA, and UA biomolecules.

Automated summary

This article reports a new method for synthesizing reduced graphene oxide/polypyrrole-platinum (rGO/PPy-Pt) nanoparticles using microwave-assisted procedure. The synthesized nanocomposites were characterized using X-Ray Diffraction Diffractometry (XRD), Scanning Electron Microscope (SEM), and Fourier Transform Infrared Spectrophotometer (FTIR). The electrocatalytic performance of rGO/PPy-Pt nanocomposites for the determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA) was evaluated through cyclic voltammetry (CV) and differential pulse voltammetry (DPV) measurements. The results indicate that the rGO/PPy-Pt bimetallic composite exhibits high electrocatalytic performance against AA, DA, and UA biomolecules.