Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 99, Pages 17584-17587Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc07697h
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Funding
- National Basic Research 973 Program [2013CB733700]
- NSFC [21125522, 21327807, 21575041]
- Shanghai Pujiang Program Grant of China [12JC1403500]
- Shanghai Municipal Natural Science Foundation [14ZR1410800]
- Fundamental Research Funds for the Central Universities [WB1113005]
- China Postdoctoral Science Foundation [2015M570335]
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Herein, a pH-sensitive probe has been designed based on DNA modified gold nanoparticles (AuNPs) for Raman/fluorescence dual-imaging of the intracellular pH distribution. In the acidic environment of cancer cells, the configuration change of DNA on the probe surface could turn on'' Raman/fluorescence signals simultaneously.
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