Journal
DRUG DISCOVERY TODAY
Volume 28, Issue 11, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2023.103766
Keywords
pediatric; medication adherence; dosage form; design strategies
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Medication adherence is crucial for drug development and dosage form design in pediatric patients, as it not only ensures effective treatment outcomes but also reduces medical costs. Accurately identifying differences in medication adherence between children and adults and analyzing the related factors is essential for guiding the development of pediatric drugs. This review focuses on factors influencing pediatric medication adherence and pharmaceutical design strategies to improve adherence, providing comprehensive summaries of new dosage forms, technologies, and devices' advantages and limitations.
Medication adherence in pediatric patients is a key factor in drug development and dosage form design. High medication adherence is not only important to achieve the expected treatment effects but can also effectively reduce medical costs. It is an ongoing task to accurately identify differences in medication adherence between children and adults and analyze the factors related to pediatric medication adherence. This is necessary to guide the development of pediatric drugs. This review focuses on factors that influence pediatric medication adherence as well as pharmaceutical design strategies to improve adherence. Current new dosage forms, new technologies, and new devices are comprehensively summarized in terms of their advantages and limitations.
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