Journal
DIABETES RESEARCH AND CLINICAL PRACTICE
Volume 203, Issue -, Pages -Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2023.110885
Keywords
Osteopontin; Type 2 diabetes mellitus; Diabetic cardiomyopathy; Echocardiography
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Diabetic cardiomyopathy is characterized by restrictive pattern and the risk of heart failure. The osteopontin (OPN) was independently associated with left ventricular diastolic dysfunction and increased with the severity of DbCM.
Diabetic cardiomyopathy (DbCM) is characterized by restrictive pattern and consistent risk of overt heart failure. We here focused osteopontin (OPN), which was tested independently associated with left ventricular diastolic dysfunction (LVDD). Overall, OPN increased with DbCM severity according with the presence of left atrial dilatation, LV hypertrophy and LVDD.
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