Oral health status and risk of incident diabetes: A prospective cohort study of 213,389 individuals aged 45 and over

Aims: To examine whether simple measures of oral health are associated with incident diabetes.Methods: This prospective cohort study linked data from the 45 and Up Study, Australia, to administrative health records. The study participants were 213,389 men and women, aged & GE;45 years, with no diabetes at baseline. The oral health of participants was assessed by questionnaire. Incident diabetes cases were ascertained based on selfreport in follow-up questionnaires, linked data on medical and pharmaceutical claims, and hospitalisation data up until 2019. The association between oral health and incident diabetes were calculated using multivariable cox proportional hazards models. Results: During 2,232,215 person-years of follow-up, 20,487 (9.6%) participants developed diabetes. Compared with those with & GE;20 teeth, the adjusted hazard ratio (aHR) for incident diabetes was 1.12 (95% Confidence Interval (CI): 1.08, 1.17) for 10-19 teeth, 1.20 (1.14, 1.26) for 1-9 teeth and 1.15 (1.09, 1.21) for no teeth. Compared with those with excellent/very good teeth and gums, the aHR for incident diabetes was 1.07 (1.03, 1.12) for fair and 1.13 (1.07, 1.20) for poor teeth and gums.Conclusions: Simple measures of oral health were associated with risk of developing diabetes, demonstrating the potential importance of oral health screening for diabetes prevention.

Automated summary

This study found that oral health status is associated with the risk of developing diabetes, highlighting the importance of oral health screening for diabetes prevention.