Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 30, Pages 6629-6632Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc01116g
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Funding
- National Natural Science Foundation of China [21472056, 21272085]
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A copper-catalyzed domino protocol for the synthesis of 2-(1,3,4-oxadiazol-2-yl)aniline derivatives has been developed from simple and available isatins and hydrazides. This domino process integrated consecutive condensation, base-promoted ring-opening and the key copper-catalyzed decarboxylative coupling for intramolecular C-O bond formation.
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