☆ 4.3 Review

Gut Microbiota and Its Role in the Brain-Gut-Kidney Axis in Hypertension

CURRENT HYPERTENSION REPORTS (2023)

Related references

Note: Only part of the references are listed.

Review Urology & Nephrology

The gut microbiome and hypertension

Joanne A. O'Donnell et al.

Summary: A large body of evidence has shown that the gut microbiome plays a role in regulating blood pressure through various mechanisms, including changes in gene pathways and the production of beneficial or detrimental metabolites. Dysbiosis in the gut microbiome can result in inflammation and disruption of the intestinal barrier, activating mechanisms associated with blood pressure regulation. Challenges in gut microbiome research include minimizing confounding factors and establishing causality, but new approaches such as clinical trials and computational methods offer potential for leveraging the microbiome to lower blood pressure.

NATURE REVIEWS NEPHROLOGY (2023)

Add to Collection

Article Medicine, General & Internal

Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension

Mason W. W. Freeman et al.

Summary: Baxdrostat, a new drug that selectively inhibits aldosterone synthase, has been shown to effectively reduce blood pressure in patients with treatment-resistant hypertension.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

Add to Collection

Article Cardiac & Cardiovascular Systems

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage

Ellen G. Avery et al.

Summary: This study investigated the impact of microbial colonization on organ damage in hypertension using germ-free and colonized mice models. The results showed that the kidney is more sensitive to microbial influence, and the colonization status is associated with circulating metabolites and inflammatory cells relevant to hypertension.

CARDIOVASCULAR RESEARCH (2023)

Add to Collection

Article Immunology

Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets

Zenglei Zhang et al.

Frontiers in Immunology (2023)

Add to Collection

Review Biochemistry & Molecular Biology

The Role of Next-Generation Probiotics in Obesity and Obesity-Associated Disorders: Current Knowledge and Future Perspectives

Natalia G. Vallianou et al.

Summary: Obesity and obesity-associated disorders are major health issues worldwide. Next-generation probiotics (NGPs) are showing promise as potential preventive and therapeutic agents against obesity, with candidate NGPs like Akkermansia muciniphila and Hafnia alvei already demonstrating encouraging results. However, safety issues and strict regulations should be continuously addressed. This review explores the current knowledge regarding NGPs, their utility in obesity and obesity-related disorders, their safety profile, and their therapeutic potential in overweight/obese individuals.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection

Article Endocrinology & Metabolism

Aldosterone Synthase Inhibitors and the Treatment of Essential Hypertension

Celso E Gomez-Sanchez et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2023)

Add to Collection

Article Medicine, Research & Experimental

suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury

Christian Nusshag et al.

Summary: A study on 200 critically ill patients meeting Sepsis-3 criteria found that serum levels of soluble urokinase plasminogen activator receptor (suPAR) can effectively determine the severity and progression of sepsis-induced acute kidney injury (SI-AKI), providing improved prediction of renal replacement therapy and mortality compared to traditional kidney biomarkers. Experiments on mice demonstrated that suPAR deficiency protects against SI-AKI, while suPAR overexpression leads to more severe kidney damage and poorer survival, accompanied by increased chemotactic factors and T cell infiltration in the kidneys. Therefore, suPAR allows for an immune-derived and kidney function-independent staging of SI-AKI and offers improved longitudinal risk stratification.

JCI INSIGHT (2023)

Add to Collection

Review Food Science & Technology

Efficacy of synbiotic interventions on blood pressure: a systematic review and meta-analysis of clinical trials

Amir Hadi et al.

Summary: Synbiotic interventions significantly reduce systolic blood pressure in adults, especially in longer trials, as supplements, and with younger participants. Significant improvements in both systolic and diastolic blood pressure levels were seen in subgroups with lower body mass index (<30 kg/m(2)).

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Public human microbiome data are dominated by highly developed countries

Richard J. Abdill et al.

Summary: This study analyzed the country of origin of over 440,000 human microbiome samples from the world's largest genomic data repositories. The results revealed an imbalance in sampling, with a majority of samples coming from Europe, the United States, and Canada, while central and southern Asia were underrepresented. This highlights the need for more global representation in microbiome studies.

PLOS BIOLOGY (2022)

Add to Collection

Review Biochemistry & Molecular Biology

Understanding the Role of the Gut Microbiome and Microbial Metabolites in Non-Alcoholic Fatty Liver Disease: Current Evidence and Perspectives

Natalia Vallianou et al.

Summary: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, often starting as a benign liver fat accumulation that can progress to non-alcoholic steatohepatitis (NASH) and increase the risk of cirrhosis and hepatocellular carcinoma (HCC). Recent studies have highlighted the role of gut dysbiosis, which can lead to increased gut permeability and the release of toxic bacterial products and proinflammatory cytokines, causing and sustaining inflammation. The composition of the gut microbiota and various metabolites may vary during different stages of NAFLD and among population groups, and further research is needed to determine the causal relationship between gut microbiota profiles and NAFLD in patients. Additionally, multiple metabolites may contribute to the pathogenesis of NAFLD.

BIOMOLECULES (2022)

Add to Collection

Review Peripheral Vascular Disease

How Dietary Fibre, Acting via the Gut Microbiome, Lowers Blood Pressure

Chudan Xu et al.

Summary: A high-fibre diet lowers blood pressure through gut microbiome metabolites, preventing cardiovascular disease, but the exact mechanisms are not fully understood. Lack of dietary fibre can lead to changes in gut microbiota and increased blood pressure.

CURRENT HYPERTENSION REPORTS (2022)

Add to Collection

Article Peripheral Vascular Disease

Association Between the Gut Microbiome and Their Metabolites With Human Blood Pressure Variability

Evany Dinakis et al.

Summary: This study found that the diversity of the gut microbiome, levels of microbial metabolites, and specific bacteria were associated with blood pressure variability. Alistipesfinegoldii and Lactobacillus were associated with lower blood pressure variability, while Prevotella and Clostridium were associated with higher blood pressure variability.

HYPERTENSION (2022)

Add to Collection

Review Biochemistry & Molecular Biology

Rejuvenating the human gut microbiome

Shanlin Ke et al.

Summary: Industrial advances have led to a significant reduction in diversity in our gut microbiome, making us more susceptible to diseases. Rewilding the human gut microbiome has been a hot topic of debate, and this article proposes an alternative solution of rejuvenating the gut microbiome through stool banking and autologous fecal microbiota transplantation.

TRENDS IN MOLECULAR MEDICINE (2022)

Add to Collection

Review Medicine, Research & Experimental

The potential impact of a probiotic: Akkermansia muciniphila in the regulation of blood pressure-the current facts and evidence

Arun Prasath Lakshmanan et al.

Summary: Akkermansia muciniphila (A. muciniphila) is a widely studied probiotic that has been found to have potential positive and negative impacts on hypertension. This review aims to discuss the role of A. muciniphila in the pathophysiology of hypertension and its potential effects on hypertension management.

JOURNAL OF TRANSLATIONAL MEDICINE (2022)

Add to Collection

Article Medicine, Research & Experimental

Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis

George Hindy et al.

Summary: This study investigated the pathogenic involvement of soluble urokinase plasminogen activator receptor (suPAR) in atherosclerosis. The researchers found that suPAR levels were predictive of coronary artery calcification and cardiovascular events. Through genetic analysis and experimental models, they identified a variant in the PLAUR gene that led to higher suPAR levels and confirmed a causal association between suPAR levels and atherosclerotic phenotypes. The study also found that suPAR affected monocyte function, leading to increased inflammation and chemotaxis.

JOURNAL OF CLINICAL INVESTIGATION (2022)

Add to Collection

Article Medicine, Research & Experimental

Clinical, genetic, and experimental increase in soluble urokinase plasminogen activator receptor levels promotes atherosclerosis

George Hindy et al.

Summary: The study using epidemiologic, genetic, and experimental approaches found that suPAR is a pathogenic factor for atherosclerosis, with its levels strongly associated with cardiovascular outcomes and predictive of coronary artery calcification. The missense variant rs4760 in the PLAUR gene leads to higher suPAR levels, and Mendelian randomization analysis confirms a causal relationship between genetically predicted suPAR levels and atherosclerotic phenotypes. In experimental models, increased suPAR levels modulate monocyte function to promote atherosclerosis.

JOURNAL OF CLINICAL INVESTIGATION (2022)

Add to Collection

Review Transplantation

The consequences of altered microbiota in immune-related chronic kidney disease

Wei Ling Lau et al.

Summary: The normal gut microbiome plays a crucial role in regulating host immunity and enterocyte metabolism. Chronic kidney disease can lead to dysbiosis and intestinal inflammation. Shifts in bacterial populations in the gut may contribute to the production of metabolites that affect the host immune system.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

Add to Collection

Article Infectious Diseases

European Society of Clinical Microbiology and Infectious Diseases: 2021 update on the treatment guidance document for Clostridioides difficile infection in adults

Joffrey van Prehn et al.

Summary: The document provides guidance on the treatment of Clostridioides difficile infection with a focus on the best treatment methods and factors influencing treatment strategies.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

Add to Collection

Article Genetics & Heredity

Large-scale association analyses identify host factors influencing human gut microbiome composition

Alexander Kurilshikov et al.

Summary: The study revealed significant effects of host genetic variation on microbial composition, with the lactase (LCT) gene locus showing an age-dependent association with Bifidobacterium abundance. Other associations, while suggestive, were enriched for taxa with high heritability and for genes expressed in the intestine and brain.

NATURE GENETICS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

Francesco Asnicar et al.

Summary: The gut microbiome is influenced by diet and has significant associations with nutrients, foods, and overall dietary habits, impacting host metabolism and cardiovascular disease risk. Certain microbial species are indicators of favorable postprandial glucose metabolism, while overall microbiome composition can predict a range of cardiometabolic blood markers.

NATURE MEDICINE (2021)

Add to Collection

Review Peripheral Vascular Disease

Interleukin 17A: Key Player in the Pathogenesis of Hypertension and a Potential Therapeutic Target

Gwendolyn K. Davis et al.

Summary: IL-17A plays a key role in the pathogenesis of hypertension, promoting blood pressure increase through various mechanisms and contributing to renal and vascular dysfunction. Therapeutics targeting IL-17A show promise in both animal models and human studies for the treatment of hypertension.

CURRENT HYPERTENSION REPORTS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Reporting guidelines for human microbiome research: the STORMS checklist

Chloe Mirzayi et al.

Summary: The STORMS tool is a reporting guideline for human microbiome studies, consisting of a 17-item checklist to help researchers report study results concisely and completely, facilitating manuscript preparation, peer review, and reader comprehension.

NATURE MEDICINE (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Hypertension Do Inflammation and Immunity Hold the Key to Solving this Epidemic?

Meena S. Madhur et al.

Summary: Even after blood pressure normalization, patients with hypertension still face elevated cardiovascular risk such as stroke, heart failure, and heart attack, possibly due to underlying immune cell activation. Triggers like viral infections, autoimmunity, and lifestyle factors can initiate immune activation leading to chronic inflammation and hypertension. T cells play a central role in the immune responses contributing to hypertension.

CIRCULATION RESEARCH (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Pathophysiology of Hypertension The Mosaic Theory and Beyond

David G. Harrison et al.

Summary: Dr. Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s, advocating that hypertension is the result of many interacting factors. Over the years, new concepts have arisen that allow further refinements of the theory, emphasizing the interdependence of various nodes.

CIRCULATION RESEARCH (2021)

Add to Collection

Article Immunology

Washed Microbiota Transplantation Lowers Blood Pressure in Patients With Hypertension

Hao-Jie Zhong et al.

Summary: The study found that washed microbiota transplantation (WMT) from normotensive donors had a blood pressure-lowering effect in hypertensive patients, especially in those who underwent WMT via the lower gastrointestinal tract and in those not taking antihypertensive drugs.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Add to Collection

Review Cardiac & Cardiovascular Systems

Microbiome and hypertension: where are we now?

Natalia G. Vallianou et al.

JOURNAL OF CARDIOVASCULAR MEDICINE (2020)

Add to Collection

Article Medicine, General & Internal

Soluble Urokinase Receptor and Acute Kidney Injury

Salim S. Hayek et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Add to Collection

Article Cell Biology

Washed microbiota transplantation vs. manual fecal microbiota transplantation: clinical findings, animal studies and in vitro screening

Ting Zhang et al.

PROTEIN & CELL (2020)

Add to Collection

Article Cardiac & Cardiovascular Systems

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

David M. Kaye et al.

CIRCULATION (2020)

Add to Collection

Article Endocrinology & Metabolism

Autoantibody Production in Obesity: Is There Evidence for a Link Between Obesity and Autoimmunity?

Christina Tsigalou et al.

CURRENT OBESITY REPORTS (2020)

Add to Collection

Review Biochemistry & Molecular Biology

Physiological functions of junctional adhesion molecules (JAMs) in tight junctions

Christian Hartmann et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)

Add to Collection

Article Endocrinology & Metabolism

Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer

Faraz Bishehsari et al.

NATURE REVIEWS ENDOCRINOLOGY (2020)

Add to Collection

Article Genetics & Heredity

Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites

Chad N. Brocker et al.

HUMAN GENOMICS (2020)

Add to Collection

Article Peripheral Vascular Disease

Gut Microbiota Composition and Blood Pressure The CARDIA Study

Shan Sun et al.

HYPERTENSION (2019)

Add to Collection

Article Multidisciplinary Sciences

Mapping human microbiome drug metabolism by gut bacteria and their genes

Michael Zimmermann et al.

NATURE (2019)

Add to Collection

Article Endocrinology & Metabolism

Understanding the Role of the Gut Microbiome and Microbial Metabolites in Obesity and Obesity-Associated Metabolic Disorders: Current Evidence and Perspectives

Natalia Vallianou et al.

CURRENT OBESITY REPORTS (2019)

Add to Collection

Review Oncology

Microbiota and cancer: an update

Natalia G. Vallianou et al.

JOURNAL OF CHEMOTHERAPY (2019)

Add to Collection

Review Peripheral Vascular Disease

Guidelines for Transparency on Gut Microbiome Studies in Essential and Experimental Hypertension

Francine Z. Marques et al.

HYPERTENSION (2019)

Add to Collection

Review Microbiology

Advancing functional and translational microbiome research using meta-omics approaches

Xu Zhang et al.

MICROBIOME (2019)

Add to Collection

Article Critical Care Medicine

Neutrophils are a main source of circulating suPAR predicting outcome in critical illness

Hendrik Gussen et al.

JOURNAL OF INTENSIVE CARE (2019)

Add to Collection

Review Urology & Nephrology

The gut microbiota and the brain-gut-kidney axis in hypertension and chronic kidney disease

Tao Yang et al.

NATURE REVIEWS NEPHROLOGY (2018)

Add to Collection

Review Food Science & Technology

Uremic Toxin Clearance and Cardiovascular Toxicities

Robert D. Mair et al.

TOXINS (2018)

Add to Collection

Article Cardiac & Cardiovascular Systems

Gut microbiota and serum metabolite differences in African Americans and White Americans with high blood pressure

Jacquelyn M. Walejko et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2018)

Add to Collection

Article Peripheral Vascular Disease

Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association

Robert M. Carey et al.

HYPERTENSION (2018)

Add to Collection

Article Medicine, General & Internal

AST-120 Reduces Neuroinflammation Induced by Indoxyl Sulfate in Glial Cells

Simona Adesso et al.

JOURNAL OF CLINICAL MEDICINE (2018)

Add to Collection

Article Hematology

Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota

Kamilla S. Josefsdottir et al.

BLOOD (2017)

Add to Collection

Article Cardiac & Cardiovascular Systems

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice

Francine Z. Marques et al.

CIRCULATION (2017)

Add to Collection

Article Biochemistry & Molecular Biology

Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease

Eunsil Hahm et al.

NATURE MEDICINE (2017)

Add to Collection

Review Pediatrics

Gut microbiome and kidney disease: a bidirectional relationship

Souhaila Al Khodor et al.

PEDIATRIC NEPHROLOGY (2017)

Add to Collection

Article Biochemistry & Molecular Biology

A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease

Salim S. Hayek et al.

NATURE MEDICINE (2017)

Add to Collection

Article Pharmacology & Pharmacy

Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

Simona Adesso et al.

FRONTIERS IN PHARMACOLOGY (2017)

Add to Collection

Review Physiology

Gut-Brain Axis in Regulation of Blood Pressure

Tao Yang et al.

FRONTIERS IN PHYSIOLOGY (2017)

Add to Collection

Article Urology & Nephrology

Effect of AST-120 in Chronic Kidney Disease Treatment: Still a Controversy?

Junna Yamaguchi et al.

NEPHRON (2017)

Add to Collection

Article Nutrition & Dietetics

Effects of dietary sodium on metabolites: the Dietary Approaches to Stop Hypertension (DASH)-Sodium Feeding Study

Andriy Derkach et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2017)

Add to Collection

Article Urology & Nephrology

Metabolism, Protein Binding, and Renal Clearance of Microbiota-Derived p-Cresol in Patients with CKD

Ruben Poesen et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)

Add to Collection

Article Multidisciplinary Sciences

Gut microbiota induce IGF-1 and promote bone formation and growth

Jing Yan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Add to Collection

Review Peripheral Vascular Disease

Probiotics and blood pressure: current insights

Aditya Upadrasta et al.

INTEGRATED BLOOD PRESSURE CONTROL (2016)

Add to Collection

Review Physiology

Role of neurons and glia in the CNS actions of the renin-angiotensin system in cardiovascular control

Annette D. de Kloet et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2015)

Add to Collection

Article Peripheral Vascular Disease

Gut Dysbiosis Is Linked to Hypertension

Tao Yang et al.

HYPERTENSION (2015)

Add to Collection

Review Biochemistry & Molecular Biology

Molecular Mechanisms Underlying β-Adrenergic Receptor-Mediated Cross-Talk between Sympathetic Neurons and Immune Cells

Dianne Lorton et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Add to Collection

Review Immunology

Brain inflammation and hypertension: the chicken or the egg?

Pawel J. Winklewski et al.

JOURNAL OF NEUROINFLAMMATION (2015)

Add to Collection

Article Medicine, General & Internal

Soluble Urokinase Receptor and Chronic Kidney Disease

Salim S. Hayek et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Add to Collection

Article Urology & Nephrology

Expansion of Urease- and Uricase-Containing, Indole- and p-Cresol-Forming and Contraction of Short-Chain Fatty Acid-Producing Intestinal Microbiota in ESRD

Jakk Wong et al.

AMERICAN JOURNAL OF NEPHROLOGY (2014)

Add to Collection

Article Peripheral Vascular Disease

Effect of Probiotics on Blood Pressure A Systematic Review and Meta-Analysis of Randomized, Controlled Trials

Saman Khalesi et al.

HYPERTENSION (2014)

Add to Collection

Article Immunology

The immune system and hypertension

Madhu V. Singh et al.

IMMUNOLOGIC RESEARCH (2014)

Add to Collection

Review Immunology

The microbiome and regulation of mucosal immunity

Andrew J. McDermott et al.

IMMUNOLOGY (2014)

Add to Collection

Article Gastroenterology & Hepatology

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

Colin Hill et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)

Add to Collection

Article Gastroenterology & Hepatology

Surface area of the digestive tract - revisited

Herbert F. Helander et al.

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2014)

Add to Collection

Article Microbiology

Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics

L. Geurts et al.

BENEFICIAL MICROBES (2014)

Add to Collection

Article Urology & Nephrology

Role of Urea in Intestinal Barrier Dysfunction and Disruption of Epithelial Tight Junction in Chronic Kidney Disease

Nosratola D. Vaziri et al.

AMERICAN JOURNAL OF NEPHROLOGY (2013)

Add to Collection

Article Multidisciplinary Sciences

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

Jennifer L. Pluznick et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Add to Collection

Article Biochemical Research Methods

Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production

Yoshiharu Itoh et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2012)

Add to Collection

Article Transplantation

Disintegration of colonic epithelial tight junction in uremia: a likely cause of CKD-associated inflammation

Nosratola D. Vaziri et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)

Add to Collection

Article Urology & Nephrology

p-Cresol and Cardiovascular Risk in Mild-to-Moderate Kidney Disease

Bjorn K. I. Meijers et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)

Add to Collection

Article Urology & Nephrology

Free p-cresol is associated with cardiovascular disease in hemodialysis patients

B. K. I. Meijers et al.

KIDNEY INTERNATIONAL (2008)

Add to Collection

Article Multidisciplinary Sciences

Metagenomic analysis of the human distal gut microbiome

Steven R. Gill et al.

SCIENCE (2006)

Add to Collection

Review Multidisciplinary Sciences

Host-bacterial mutualism in the human intestine

F Bäckhed et al.

SCIENCE (2005)

Add to Collection

© Peeref 2019-2024. All rights reserved.