☆ 4.7 Article

Heterogeneous porosity design triggered stress reorganization to avoid intervertebral cage subsidence and promote spinal fusion

COMPOSITE STRUCTURES (2023)

Related references

Note: Only part of the references are listed.

Review Clinical Neurology

Factors influencing cage subsidence in anterior cervical corpectomy and discectomy: a systematic review

Utpal Kanti Dhar et al.

Summary: The present study aims to compare and synthesize the literature of both clinical and biomechanical studies to evaluate and present the factors associated with cage subsidence. A total of 49 clinical studies were included, and it was found that patients treated with the cage and plate combination had a lower subsidence rate compared to those with the stand-alone cage. Polyetheretherketone material was shown to have a lower subsidence rate than titanium and other materials, and the subsidence rate was higher at levels C5-C7 compared to levels C2-C5.

EUROPEAN SPINE JOURNAL (2023)

Add to Collection

Article Materials Science, Multidisciplinary

Additive manufacturing of multi-morphology graded titanium scaffolds f or bone implant applications

Aihua Yu et al.

Summary: Porous Titanium scaffolds with multi-morphology structures were designed and fabricated in this study, showing excellent mechanical properties and cytocompatibility. Among them, PG50 exhibited similar elastic modulus to human bone and higher strength, providing potential for bone defect restoration.

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2023)

Add to Collection

Article Engineering, Biomedical

A biomimetic gradient porous cage with a micro-structure for enhancing mechanical properties and accelerating osseointegration in spinal fusion

Cheng-Qi Jia et al.

Summary: In this study, a biomimetic gradient porous cage with a micro-structure was designed to enhance mechanical properties and accelerate spinal fusion.

BIOACTIVE MATERIALS (2023)

Add to Collection

Article Mechanics

Experimental 3D printed re-entrant auxetic and honeycomb spinal cages based on Ti-6Al-4 V: Computer-Aided design concept and mechanical characterization

V. A. Lvov et al.

Summary: This paper presents a method for modeling a biomedical device using Computer-Aided design software and characterizes the mechanical properties of experimental prototypes of interbody cages. The results show that 3D printed cells with auxetic metamaterial structures exhibit higher compressive strength and fatigue resistance compared to cells with honeycomb structures. The study also reveals the differences in mechanical behavior between the two structures and their Young modulus.

COMPOSITE STRUCTURES (2023)

Add to Collection

Article Engineering, Biomedical

Design, fabrication, and structural safety validation of 3D-printable biporous bone augments

Yeokyung Kang et al.

Summary: This study proposes three-dimensional printable bone augments as an alternative to surgeries for patients with severe bone defects in total hip arthroplasty. The bone augments are designed to bond from various angles and have good structural safety. Further research is needed to study the clinical applications of these bone augments.

BIO-DESIGN AND MANUFACTURING (2023)

Add to Collection

Article Materials Science, Multidisciplinary

Ability of a novel biomimetic titanium alloy cage in avoiding subsidence and promoting fusion: a goat spine model study

Lin-nan Wang et al.

Summary: A novel biomimetic titanium alloy cage was designed with improvements in shape, Young's modulus matching, and enhanced osteogenic properties through hydroxyapatite biocoating. Results showed a significant increase in bone ingrowth and osseointegration with the biocoating, indicating improved fusion effects and avoidance of subsidence.

MATERIALS & DESIGN (2022)

Add to Collection

Article Engineering, Multidisciplinary

Evaluation of the effect of bone plate modulus on the early bone healing of fractured tibia

Muhammad Usama Zaheer et al.

Summary: In this study, 3D-printed composite bone plates with different Young's moduli were designed and their effects on long-bone fractures were analyzed. A biphasic mechano-regulation algorithm was developed to analyze bone-healing patterns, and the results showed that the composite bone plate with a Young's modulus of 40 GPa exhibited the best healing performance.

COMPOSITES PART B-ENGINEERING (2022)

Add to Collection

Review Medicine, General & Internal

Diagnosis and Management of Lumbar Spinal Stenosis A Review

Jeffrey N. Katz et al.

Summary: Lumbar spinal stenosis is a common cause of low back and leg pain in older individuals, affecting approximately 103 million people worldwide. Most cases are treated nonoperatively, but surgery is an effective option for patients who do not improve with conservative management.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

Add to Collection

Article Engineering, Biomedical

Biodegradable interbody cages for lumbar spine fusion: Current concepts and future directions

Markus Laubach et al.

Summary: Lumbar fusion is a common treatment for spinal diseases, but current cage materials have limitations. Recently, biodegradable cages and scaffold-guided bone regeneration have shown potential for better outcomes. Surface modification of implants can also enhance tissue integration and reduce infections. Further research is needed to improve these techniques.

BIOMATERIALS (2022)

Add to Collection

Article Engineering, Biomedical

Structural optimization of patient-specific temporomandibular joint replacement implants for additive manufacturing: novel metrics for safety evaluation and biomechanical performance

Manuel Pinheiro et al.

Summary: This study develops and validates a patient-specific TMJ implant using structural optimization techniques, which can improve joint function and minimize the impact on the mandible. The optimized design of the implant restores natural strain patterns, and reduces the load transfer at the proximal ramus, resulting in improved biomechanical performance and reduced impact on mandibular strain.

BIO-DESIGN AND MANUFACTURING (2022)

Add to Collection

Article Engineering, Biomedical

Multiscale design and biomechanical evaluation of porous spinal fusion cage to realize specified mechanical properties

Hongwei Wang et al.

Summary: The study developed a porous Ti fusion cage using a multiscale optimization approach, evaluated and manufactured through numerical simulations and selective laser melting. The designed porous cage showed improved biomechanical performance, contributing to reducing the risks of cage subsidence and stress shielding.

BIO-DESIGN AND MANUFACTURING (2022)

Add to Collection

Article Engineering, Biomedical

3D printed titanium scaffolds with homogeneous diamond-like structures mimicking that of the osteocyte microenvironment and its bone regeneration study

Xuan Pei et al.

Summary: Fabricating personalized titanium scaffolds that mimic the osteocyte microenvironment is challenging due to complex geometrical cues. This study designed and produced titanium scaffolds with diamond-like structures to trigger osteocyte adhesion and migration behavior. The research also explored the effects of different geometric cues and implantation sites on bone regeneration, highlighting significant differences in in vivo experimental results.

BIOFABRICATION (2021)

Add to Collection

Article Biology

Computational comparison of three different cage porosities in posterior lumbar interbody fusion with porous cage

Yen-Nien Chen et al.

Summary: This study compared the biomechanical responses of lumbar segments with different porous cage porosities, finding that increasing porosity led to higher cage stress and contact pressure with bone fusion. Porous cages made with additive laser melting technology are becoming more popular in clinical use.

COMPUTERS IN BIOLOGY AND MEDICINE (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Design and 3D Printing of Interbody Fusion Cage Based on TPMS Porous Structure

Jinlai Qi et al.

Summary: The study proposed a fusion cage inner hole design method based on controllable TPMS-P to address the mismatch between the comprehensive mechanical properties of the fusion cage and the human body. By optimizing the topology of the porous structure implants, precise control of the overall comprehensive mechanical properties was achieved, resulting in an optimized model that matched the mechanical properties of the fusion cage.

APPLIED SCIENCES-BASEL (2021)

Add to Collection

Article Chemistry, Analytical

Design of Customize Interbody Fusion Cages of Ti64ELI with Gradient Porosity by Selective Laser Melting Process

Cheng-Tang Pan et al.

Summary: Intervertebral fusion surgery is a major operation for spinal trauma, degeneration, and deformity correction. Most fusion cages have high stiffness, leading to stress concentration and shielding effects. Using a porous structure in fusion cages can reduce stiffness and improve strength for surrounding tissues. The study designed a porous gradient structure intervertebral cage and evaluated it through simulations and mechanical property testing.

MICROMACHINES (2021)

Add to Collection

Article Medicine, General & Internal

Effect of Arthroplasty vs Fusion for Patients With Cervical Radiculopathy A Randomized Clinical Trial

Tonje Okkenhaug Johansen et al.

Summary: In this randomized clinical trial, patients treated with arthroplasty and fusion reported similar and substantial clinical improvement at 5 years.

JAMA NETWORK OPEN (2021)

Add to Collection

Article Engineering, Biomedical

In vivo analysis of post-joint-preserving surgery fracture of 3D-printed Ti-6Al-4V implant to treat bone cancer

Jong Woong Park et al.

Summary: This study investigated the impact of bone cancer on bone strength and human activity capacity, as well as methods for replacing the affected bone in patients. By developing an electron beam-melted Ti-6Al-4V implant, the ambulatory function of the patient was restored successfully, but a delayed fracture occurred at the proximal meshed junction of the implant.

BIO-DESIGN AND MANUFACTURING (2021)

Add to Collection

Review Materials Science, Multidisciplinary

Materials evolution of bone plates for internal fixation of bone fractures: A review

Junlei Li et al.

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2020)

Add to Collection

Article Cell Biology

Safety and Tolerability of Stromal Vascular Fraction Combined with β-Tricalcium Phosphate in Posterior Lumbar Interbody Fusion: Phase I Clinical Trial

Kyoung-Tae Kim et al.

CELLS (2020)

Add to Collection

Article Surgery

Risk factors of second surgery for adjacent segment disease following anterior cervical discectomy and fusion: A 16-year cohort study

Jau-Ching Wu et al.

INTERNATIONAL JOURNAL OF SURGERY (2019)

Add to Collection

Article Computer Science, Interdisciplinary Applications

Stand-alone lumbar cage subsidence: A biomechanical sensitivity study of cage design and placement

Andrea Calvo-Echenique et al.

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2018)

Add to Collection

Article Materials Science, Multidisciplinary

The biomimetic design and 3D printing of customized mechanical properties porous Ti6Al4V scaffold for load-bearing bone reconstruction

Boqing Zhang et al.

MATERIALS & DESIGN (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Titanium Fiber Plates for Bone Tissue Repair

Takashi Takizawa et al.

ADVANCED MATERIALS (2018)

Add to Collection

Review Materials Science, Biomaterials

Effects of bone substitute architecture and surface properties on cell response, angiogenesis, and structure of new bone

F. S. L. Bobbert et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

Add to Collection

Article Thermodynamics

Biomechanical evaluation of a dynamic fusion cage design for cervical spine: A finite element study

Jung-Tung Liu et al.

ADVANCES IN MECHANICAL ENGINEERING (2017)

Add to Collection

Review Engineering, Biomedical

Bone grafts and biomaterials substitutes for bone defect repair: A review

Wenhao Wang et al.

BIOACTIVE MATERIALS (2017)

Add to Collection

Article Engineering, Multidisciplinary

Biomechanical evaluation of pedicle screw fixation system in spinal adjacent levels using polyetheretherketone, carbon-fiber-reinforced polyetheretherketone, and traditional titanium as rod materials

Kyoung-Tak Kang et al.

COMPOSITES PART B-ENGINEERING (2017)

Add to Collection

Review Engineering, Biomedical

Novel bioactive materials developed by simulated body fluid evaluation: Surface-modified Ti metal and its alloys

Tadashi Kokubo et al.

ACTA BIOMATERIALIA (2016)

Add to Collection

Review Chemistry, Multidisciplinary

Mechanical meta-materials

Amir A. Zadpoor

MATERIALS HORIZONS (2016)

Add to Collection

Article Engineering, Biomedical

Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebral disc (IVD) degeneration treatment

T. Serra et al.

BIOFABRICATION (2016)

Add to Collection

Article Engineering, Biomedical

Novel strategy for mechanically tunable and bioactive metal implants

Hyun-Do Jung et al.

BIOMATERIALS (2015)

Add to Collection

Review Materials Science, Biomaterials

Bone tissue regeneration: the role of scaffold geometry

Amir A. Zadpoor

BIOMATERIALS SCIENCE (2015)

Add to Collection

Article Engineering, Biomedical

A polycaprolactone-tricalcium phosphate composite scaffold as an autograft-free spinal fusion cage in a sheep model

Yi Li et al.

BIOMATERIALS (2014)

Add to Collection

Article Engineering, Biomedical

2D and 3D Nanopatterning of Titanium for Enhancing Osteoinduction of Stem Cells at Implant Surfaces

Terje Sjoestroem et al.

ADVANCED HEALTHCARE MATERIALS (2013)

Add to Collection

Article Engineering, Biomedical

The effect of hydrofluoric acid treatment of TiO2 grit blasted titanium implants on adherent osteoblast gene expression in vitro and in vivo

Juanli Guo et al.

BIOMATERIALS (2007)

Add to Collection

Article Engineering, Biomedical

Evaluation of the osteogenesis and biodegradation of porous biphasic ceramic in the human spine

YZ Xie et al.

BIOMATERIALS (2006)

Add to Collection

Article Engineering, Biomedical

Osteoinduction of porous bioactive titanium metal

S Fujibayashi et al.

BIOMATERIALS (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.