Aging Skin and Wound Healing

Evidence for age-related effects on wound healing has been derived mostly from empirical observations without adjustment for confounders. Changes in the structure of the skin have been observed with aging, but the effects in skin unexposed to solar radiation appear modest. The clinical impact of these changes in acute wound healing seems to be small in comparison to other factors. Poor healing of chronic wounds, predominantly seen in older populations, is more often attributable to comorbid conditions rather than age alone.

Automated summary

The evidence for age-related effects on wound healing is mostly based on empirical observations without adjusting for confounding factors. Skin structure changes with aging, but the impact on unexposed skin seems to be minimal. The clinical impact of these changes on acute wound healing appears to be small compared to other factors. Poor healing of chronic wounds, mainly observed in older populations, is often attributed to comorbid conditions rather than age alone.