Related references
Note: Only part of the references are listed.PACSIN2 as a modulator of autophagy and mercaptopurine cytotoxicity: mechanisms in lymphoid and intestinal cells
Giulia Zudeh et al.
LIFE SCIENCE ALLIANCE (2023)
PACSIN proteins in vivo: Roles in development and physiology
Vincent Dumont et al.
ACTA PHYSIOLOGICA (2022)
Association of ITPA gene polymorphisms with adverse effects of AZA/6-MP administration: a systematic review and meta-analysis
Evaggelia Barba et al.
PHARMACOGENOMICS JOURNAL (2022)
LC-MS/MS Method for Measurement of Thiopurine Nucleotides (TN) in Erythrocytes and Association of TN Concentrations With TPMT Enzyme Activity
Amol O. Bajaj et al.
FRONTIERS IN PHARMACOLOGY (2022)
Effect of ITPA Polymorphism on Adverse Drug Reactions of 6-Mercaptopurine in Pediatric Patients with Acute Lymphoblastic Leukemia: A Systematic Review and Meta-Analysis
Yeonhong Lee et al.
PHARMACEUTICALS (2022)
Pharmacogenetic studies of thiopurine methyltransferase genotype-phenotype concordance and effect of methotrexate on thiopurine metabolism
Anna Zimdahl Kahlin et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2021)
An exploration of mercaptopurine/methotrexate tolerance during maintenance therapy in children with acute lymphoblastic leukemia
A. C. Whiley et al.
JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2021)
Quantification of Thioguanine in DNA Using Liquid Chromatography-Tandem Mass Spectrometry for Routine Thiopurine Drug Monitoring in Patients With Pediatric Acute Lymphoblastic Leukemia
Rihwa Choi et al.
ANNALS OF LABORATORY MEDICINE (2021)
A Novel ELISA-Based Peptide Biosensor Assay for Screening ABL1 Activity in vitro: A Challenge for Precision Therapy in BCR-ABL1 and BCR-ABL1 Like Leukemias
Oksana Montecchini et al.
FRONTIERS IN PHARMACOLOGY (2021)
Understanding thiopurine methyltransferase polymorphisms for the targeted treatment of hematologic malignancies
R. Franca et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2021)
The future of cellular immunotherapy for childhood leukemia
Challice L. Bonifant et al.
CURRENT OPINION IN PEDIATRICS (2020)
PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly
Lap P. Nguyen et al.
JOURNAL OF VIROLOGY (2020)
PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients
Raffaella Franca et al.
PHARMACOGENOMICS JOURNAL (2020)
How I treat relapsed acute lymphoblastic leukemia in the pediatric population
Stephen P. Hunger et al.
BLOOD (2020)
Precision medicine in acute lymphoblastic leukemia
Ching-Hon Pui
FRONTIERS OF MEDICINE (2020)
Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study
Carmelo Rizzari et al.
HAEMATOLOGICA (2019)
RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spread
Allen G. Sanderlin et al.
MOLECULAR BIOLOGY OF THE CELL (2019)
Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update
Mary Relling et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2019)
Individualized 6-mercaptopurine increments in consolidation treatment of childhood acute lymphoblastic leukemia: A NOPHO randomized controlled trial
Morten Tulstrup et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2018)
Adherence to Oral Medications During Maintenance Therapy Among Children and Adolescents With Acute Lymphoblastic Leukemia: A Medication Refill Analysis
Yelena P. Wu et al.
JOURNAL OF PEDIATRIC ONCOLOGY NURSING (2018)
Acute lymphoblastic leukemia in adolescent and young adults: treat as adults or as children?
Nicolas Boissel et al.
BLOOD (2018)
Targeting Kinase-activating Genetic Lesions to Improve Therapy of Pediatric Acute Lymphoblastic Leukemia
Raffaella Franca et al.
CURRENT MEDICINAL CHEMISTRY (2018)
HIV-1 gag recruits PACSIN2 to promote virus spreading
Sergei Popov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Pharmacogenetics and induction/consolidation therapy toxicities in acute lymphoblastic leukemia patients treated with AIEOP-BFM ALL 2000 protocol
R. Franca et al.
PHARMACOGENOMICS JOURNAL (2017)
Mercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group Study AALL03N1
Wendy Landier et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial
Stine Nygaard Nielsen et al.
LANCET ONCOLOGY (2017)
The Promise of Pharmacogenomics in Reducing Toxicity During Acute Lymphoblastic Leukemia Maintenance Treatment
Shoshana Rudin et al.
GENOMICS PROTEOMICS & BIOINFORMATICS (2017)
Epratuzumab and Blinatumomab as Therapeutic Antibodies for Treatment of Pediatric Acute Lymphoblastic Leukemia: Current Status and Future Perspectives
Raffaella Franca et al.
CURRENT MEDICINAL CHEMISTRY (2017)
Comparison of self-report and electronic monitoring of 6MP intake in childhood ALL: a Children's Oncology Group study
Wendy Landier et al.
BLOOD (2017)
Thiopurine Prodrugs Mediate Immunosuppressive Effects by Interfering with Rac1 Protein Function
Jin-Young Shin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity
Takaya Moriyama et al.
NATURE GENETICS (2016)
Maintenance therapy of childhood acute lymphoblastic leukemia revisitedShould drug doses be adjusted by white blood cell, neutrophil, or lymphocyte counts?
Kjeld Schmiegelow et al.
PEDIATRIC BLOOD & CANCER (2016)
Systemic Exposure to Thiopurines and Risk of Relapse in Children With Acute Lymphoblastic Leukemia A Children's Oncology Group Study
Smita Bhatia et al.
JAMA ONCOLOGY (2015)
Mercaptopurine/Methotrexate Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia: Clinical Facts and Fiction
Kjeld Schmiegelow et al.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2014)
Differential role of thiopurine methyltransferase in the cytotoxic effects of 6-mercaptopurine and 6-thioguanine on human leukemia cells
Hazhar Karim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Methotrexate binds to recombinant thiopurine S-methyltransferase and inhibits enzyme activity after high-dose infusions in childhood leukaemia
Patricia Wennerstrand et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2013)
PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity
Gabriele Stocco et al.
HUMAN MOLECULAR GENETICS (2012)
Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy
Tiphaine Adam de Beaumais et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2011)
Individualized toxicity-titrated 6-mercaptopurine increments during high-dose methotrexate consolidation treatment of lower risk childhood acute lymphoblastic leukaemia. A Nordic Society of Paediatric Haematology and Oncology (NOPHO) pilot study
Thomas L. Frandsen et al.
BRITISH JOURNAL OF HAEMATOLOGY (2011)
The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration
Bart-Jan de Kreu et al.
JOURNAL OF CELL SCIENCE (2011)
PharmGKB summary: methotrexate pathway
Torben S. Mikkelsen et al.
PHARMACOGENETICS AND GENOMICS (2011)
Thiopurine pathway
Gianluigi Zaza et al.
PHARMACOGENETICS AND GENOMICS (2010)
Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a caucasian population
M Shipkova et al.
CLINICAL CHEMISTRY (2006)
Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment
G Zaza et al.
BLOOD (2005)
Intensification of mercaptopurine/methotrexate maintenance chemotherapy may increase the risk of relapse for some children with acute lymphoblastic leukemia
K Schmiegelow et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Six months of maintenance chemotherapy after intensified treatment for acute lymphoblastic leukemia of childhood
Y Toyoda et al.
JOURNAL OF CLINICAL ONCOLOGY (2000)
Share Paper
