4.7 Article

Cardiometabolic benefits of Lacticaseibacillus paracasei 8700:2: A randomized double-blind placebo-controlled trial

Related references

Note: Only part of the references are listed.
Review Endocrinology & Metabolism

Gut barrier disruption and chronic disease

Jan Martel et al.

Summary: This article discusses the protective role of the intestinal barrier against gut microbes, food antigens, and toxins, as well as key factors associated with disease development and inflammation. In addition to known intestinal diseases, recent research indicates that intestinal barrier and microbiota dysbiosis may be closely linked to the development of metabolic, autoimmune, and aging-related disorders.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2022)

Article Biochemistry & Molecular Biology

Strain-specific regulative effects of Lactobacillus plantarum on intestinal barrier dysfunction are associated with their capsular polysaccharides

Yang Liu et al.

Summary: This study investigated the strain-specific effects of 55 L. plantarum strains on the intestinal barrier. It found that the ability of L. plantarum to regulate the intestinal barrier is exerted in part by genes encoding proteins associated with polysaccharide synthesis. The study also identified different effects of L. plantarum strains on intestinal barrier dysfunction and suggested that the capsular polysaccharides of L. plantarum may be explored as a potential functional food component against intestinal barrier dysfunction.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Nutrition & Dietetics

The effects of Aronia berry (poly)phenol supplementation on arterial function and the gut microbiome in middle aged men and women: Results from a randomized controlled trial

Melanie Le Sayec et al.

Summary: Berry (poly)phenol consumption improves arterial function in prehypertensive middle-aged individuals, possibly through modulation of gut microbiome richness and composition.

CLINICAL NUTRITION (2022)

Article Microbiology

Long-term use of Lacticaseibacillus paracasei N1115 from early life alleviates high-fatdiet-induced obesity and dysmetabolism in mice

Z. H. Miao et al.

Summary: Obesity is a serious public health problem worldwide, and the gut microbiota has been found to play a role in host metabolism. A study showed that long-term use of Lacticaseibacillus paracasei N1115, a potential probiotic strain, can alleviate obesity and metabolic disorders by influencing the gut microbiota.

BENEFICIAL MICROBES (2022)

Review Cardiac & Cardiovascular Systems

Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardioloy working Groups on Artherosclerosis and Vascular Biology, Aorta and Perirpheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis

Yvonne Alexander et al.

Summary: Endothelial cells play a crucial role in cardiovascular health, and dysfunction can be caused by cardiovascular risk factors but restored once stimuli are removed. There are various methods to measure endothelial function, with each having its pros and cons. It is recommended to adopt a consensus methodology like flow-mediated dilatation and establish reference values for different populations. Future studies should explore the integration of endothelial function measurements with patient-specific epigenetic data and other biomarkers.

CARDIOVASCULAR RESEARCH (2021)

Article Food Science & Technology

Potential mechanisms underlying the ameliorative effect of Lactobacillus paracasei FZU103 on the lipid metabolism in hyperlipidemic mice fed a high-fat diet

Xu-Cong Lv et al.

Summary: The study demonstrated that Lactobacillus paracasei FZU103 can effectively improve hepatic lipid accumulation caused by a high-fat diet, reduce body weight and fat tissue, improve biochemical parameters, promote bile acid excretion, and influence the composition of intestinal microbiota.

FOOD RESEARCH INTERNATIONAL (2021)

Review Nutrition & Dietetics

Influence of Mediterranean Diet on Human Gut Microbiota

Giuseppe Merra et al.

Summary: Changes in gut microbiota are correlated with health status, with the Mediterranean diet shown to modulate gut microbiota, increase diversity, and potentially prevent the onset of chronic non-communicable degenerative diseases. Additional controlled intervention studies are needed to further understand the correlations between dietary patterns and gut microbiota composition and activity.

NUTRIENTS (2021)

Article Cardiac & Cardiovascular Systems

Effects of a 2-Year Primary Care Lifestyle Intervention on Cardiometabolic Risk Factors A Cluster-Randomized Trial

Christoph Hochsmann et al.

Summary: A pragmatic ILI delivered in primary care setting produced clinically relevant improvements in cardiometabolic health in underserved population over 24 months, including significant weight loss and improvements in blood glucose, cholesterol levels.

CIRCULATION (2021)

Article Biotechnology & Applied Microbiology

Lactobacillus paracasei DTA81, a cholesterol-lowering strain having immunomodulatory activity, reveals gut microbiota regulation capability in BALB/c mice receiving high-fat diet

A. Tarrah et al.

Summary: This study evaluated the cholesterol-lowering probiotic strain Lactobacillus paracasei DTA81 in Balb/c mice receiving a high-fat diet, revealing a significant reduction in total cholesterol and fasting blood sugar levels, as well as an increase in Bacteroidetes and Coprococcus taxa in the gut microbiota after treatment. The in-vitro and in-vivo properties of DTA81 were also explored, showing potential for metabolic homeostasis and reducing coronary heart disease risk.

JOURNAL OF APPLIED MICROBIOLOGY (2021)

Article Medical Laboratory Technology

Long-chain monounsaturated fatty acids improve endothelial function with altering microbial flora

Rie Tsutsumi et al.

Translational Research (2021)

Article Cardiac & Cardiovascular Systems

Remnant cholesterol predicts cardiovascular disease beyond LDL and ApoB: a primary prevention study

Renato Quispe et al.

Summary: High remnant cholesterol (RC) levels are associated with ASCVD in individuals without known ASCVD, independent of traditional risk factors, LDL-C, and apoB levels. The discordant group with high RC/low LDL-C, but not the low RC/high LDL-C group, showed increased ASCVD risk compared to the concordant group.

EUROPEAN HEART JOURNAL (2021)

Review Nutrition & Dietetics

Effect of Diet and Dietary Components on the Composition of the Gut Microbiota

Ashley Beam et al.

Summary: This review explores the impact of different diets on the gut microbiota composition, finding that specific dietary components in plant-based and Mediterranean diets can influence microbial composition and bacterial metabolites, which in turn affect systemic inflammation and metabolic endotoxemia. These associations between diet/dietary components and altering bacterial composition may provide potential therapeutic targets for type II diabetes, obesity, and inflammatory diseases.

NUTRIENTS (2021)

Article Food Science & Technology

Influence of Lactobacillus paracasei HII01 Supplementation on Glycemia and Inflammatory Biomarkers in Type 2 Diabetes: A Randomized Clinical Trial

Parichart Toejing et al.

Summary: The probiotic L. paracasei HII01 showed effectiveness in improving glycemia and reducing inflammatory markers in T2DM patients, likely by modifying gut microbiota to ameliorate leaky gut and endotoxemia.

FOODS (2021)

Article Biochemistry & Molecular Biology

Lactobacillus paracasei modulates the gut microbiota and improves inflammation in type 2 diabetic rats

Zhu Zeng et al.

Summary: The study showed that treatment with L. paracasei NL41 significantly improved the inflammatory status of T2D rats, reduced the levels of inflammatory markers, and protected gut barrier function. Furthermore, NL41 altered the gut microbiota structure and enriched beneficial microorganisms, indicating a close relationship between the amelioration of inflammation and key species of the gut microbiota.

FOOD & FUNCTION (2021)

Review Cardiac & Cardiovascular Systems

Gut Microbiota and Cardiovascular Disease

Marco Witkowski et al.

CIRCULATION RESEARCH (2020)

Article Cardiac & Cardiovascular Systems

Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease

Olga Castaner et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

Expert consensus and evidence-based recommendations for the assessment of flow-mediated dilation in humans

Dick H. J. Thijssen et al.

EUROPEAN HEART JOURNAL (2019)

Article Biochemistry & Molecular Biology

Administration of Lactobacillus paracasei ameliorates type 2 diabetes in mice

Fangfang Dang et al.

FOOD & FUNCTION (2018)

Article Hematology

Endothelial Functions

Shigeo Godo et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)

Article Cardiac & Cardiovascular Systems

Validation of a new method for non-invasive assessment of vasomotor function

Elizabeth A. Ellins et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

Michael A. Gimbrone et al.

CIRCULATION RESEARCH (2016)

Review Medicine, General & Internal

The Human Intestinal Microbiome in Health and Disease

Susan V. Lynch et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Immunology

Risk and Safety of Probiotics

Shira Doron et al.

CLINICAL INFECTIOUS DISEASES (2015)

Article Endocrinology & Metabolism

Reduced Time Points to Calculate the Composite Index

R. A. DeFronzo et al.

DIABETES CARE (2010)

Review Cardiac & Cardiovascular Systems

The Metabolic Syndrome and Cardiovascular Risk A Systematic Review and Meta-Analysis

Salvatore Mottillo et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

Review Endocrinology & Metabolism

The Metabolic Syndrome

Marc-Andre Cornier et al.

ENDOCRINE REVIEWS (2008)

Article Biochemistry & Molecular Biology

Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens

Garry S. A. Myers et al.

GENOME RESEARCH (2006)

Article Biotechnology & Applied Microbiology

Probiotic lactobacilli enhance eradication on Salmonella Typhimurium in animal model

P Hütt et al.

JOURNAL OF APPLIED MICROBIOLOGY (2006)

Article Sport Sciences

International physical activity questionnaire:: 12-country reliability and validity

CL Craig et al.

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2003)