4.7 Article

Viewpoint: Antimicrobial Resistance Diagnostics Use Accelerator: Qualitative Research on Adherence to Prescriptions

Journal

CLINICAL INFECTIOUS DISEASES
Volume 77, Issue -, Pages S206-S210

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciad323

Keywords

adherence; prescription; antibiotic; determinants; behaviors

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This article explores the determinants of patients' prescription adherence behaviors, finding that basic knowledge and understanding of prescription instructions are crucial for adherence and can be improved through better communication. However, there are various other factors that influence adherence, some of which can be influenced through tailored communication messages from healthcare workers. These messages may contribute to changes in adherence behavior, but additional interventions may be needed for effectiveness.
In this Viewpoint, the authors explore the determinants of patients' prescription adherence behaviors as part of FIND's Advancing Access to Diagnostic Innovation essential for Universal Health Coverage and AMR Prevention (ADIP) trials (ClinicalTrials.gov identifier: NCT04081051). Research findings from Burkina Faso, Ghana, and Uganda show that basic knowledge and understanding of prescription instructions are essential for adherence and can be improved through better communication. However, there are a range of other factors that influence adherence, some of which can be influenced through tailored communication messages from healthcare workers. These messages may contribute to changes in adherence behavior but may require other reinforcing interventions to be effective. Finally, there are some drivers of nonadherence centered around costs and time pressure that require other forms of intervention. In this Viewpoint, we explore the determinants of patients' prescription adherence behaviors as part of the Antimicrobial Resistance Diagnostics Use Accelerator clinical trial in Burkina Faso, Ghana, and Uganda.

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