4.5 Article

Circulating interleukin-39 as a potential biomarker for rheumatoid arthritis diagnosis

Related references

Note: Only part of the references are listed.
Article

A novel Link of Serum IL-39 Levels in Patients with Rheumatoid Arthritis

Zahraa Adnan Ghadhban Al Ghuraibawi et al.

Iraqi Journal of Science (2023)

Article Biochemistry & Molecular Biology

Inflammation and Bone Metabolism in Rheumatoid Arthritis: Molecular Mechanisms of Joint Destruction and Pharmacological Treatments

Kazuhiro Maeda et al.

Summary: Rheumatoid arthritis is an inflammatory disease characterized by polyarthritis, leading to irreversible bone and joint destruction and physical disabilities. Preventing the progression of bone and joint destruction is crucial, and recent studies have shed light on its molecular mechanisms.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Immunology

Interleukin-39 exacerbates concanavalin A-induced liver injury

Yan Li et al.

Summary: Our study demonstrated that IL-39 exacerbates ConA-induced hepatitis by increasing serum ALT and AST levels, inflammatory infiltration, and hepatocyte necrosis. Additionally, IL-39 administration significantly elevated interferon-gamma, tumor necrosis factor-alpha, and IL-17A levels in ConA-induced hepatitis.

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2021)

Article Immunology

Serum IL-35 is decreased in overweight patients with rheumatoid arthritis: its correlation with Th1/Th2/Th17-related cytokines

Yuxuan Li et al.

Summary: The study found that serum IL-35 levels were associated with obesity in patients with rheumatoid arthritis (RA). Overweight patients with RA had significantly lower IL-35 levels compared to lean patients and showed characteristic immunological features of Th1/Th2/Th17-related cytokines.

BMC IMMUNOLOGY (2021)

Article Biochemistry & Molecular Biology

IL-39 increases ROS production and promotes the phosphorylation of p38 MAPK in the apoptotic cardiomyocytes

Wei Xiong et al.

Summary: IL-39 promotes intracellular reactive oxygen species production in cardiomyocytes, induces the generation of CCL2 and stimulates the apoptotic process, resulting in cardiomyocyte apoptosis.

FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2021)

Review Medicine, Research & Experimental

IL-12 and IL-23/Th17 axis in systemic lupus erythematosus

Maddalena Larosa et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2019)

Article Medicine, General & Internal

Elevated serum IL-35 levels in rheumatoid arthritis are associated with disease activity

Yuxuan Li et al.

JOURNAL OF INVESTIGATIVE MEDICINE (2019)

Article Immunology

Natural IgM and the Development of B Cell-Mediated Autoimmune Diseases

Trang T. T. Nguyen et al.

CRITICAL REVIEWS IN IMMUNOLOGY (2016)

Article Immunology

A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice

Xiaoqian Wang et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2016)

Article Biochemistry & Molecular Biology

Circulating IL-27 Is Elevated in Rheumatoid Arthritis Patients

Xiaofei Lai et al.

MOLECULES (2016)

Article Medicine, Research & Experimental

Interleukin-6 (IL-6) Receptor Antagonist Protects Against Rheumatoid Arthritis

Songsong Li et al.

MEDICAL SCIENCE MONITOR (2016)

Article Mathematical & Computational Biology

THE ROLE OF THE CYTOKINES IL-27 AND IL-35 IN CANCER

Avner Friedman et al.

MATHEMATICAL BIOSCIENCES AND ENGINEERING (2015)

Article Rheumatology

Interleukin-17 gene expression in patients with rheumatoid arthritis

Mika Kohno et al.

Modern Rheumatology (2014)

Article Rheumatology

Possible roles of IL-12-family cytokines in rheumatoid arthritis

Richard M. Pope et al.

NATURE REVIEWS RHEUMATOLOGY (2013)

Article Biochemistry & Molecular Biology

In vivo action of IL-27: reciprocal regulation of Th17 and Treg cells in collagen-induced arthritis

Su-Jin Moon et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2013)

Review Immunology

IL-12 family cytokines: immunological playmakers

Dario A. A. Vignali et al.

NATURE IMMUNOLOGY (2012)

Review Rheumatology

Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

Georg Schett et al.

NATURE REVIEWS RHEUMATOLOGY (2012)

Article Immunology

The environment, geo-epidemiology, and autoimmune disease: Rheumatoid arthritis

Gabriel J. Tobon et al.

AUTOIMMUNITY REVIEWS (2010)

Review Immunology

IL-23 in the Pathogenesis of Rheumatoid Arthritis

A. Paradowska-Gorycka et al.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2010)