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Bridging the gaps: management of lichen planus subtypes in a joint dermatology-oral surgery clinic

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CLINICAL AND EXPERIMENTAL DERMATOLOGY
Volume -, Issue -, Pages -

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OXFORD UNIV PRESS
DOI: 10.1093/ced/llad335

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Lichen planus is a complex dermatological condition that affects the skin, nails, and mucosa. The exact cause is still unclear and treatment options are limited. Severe oral mucosal involvement is challenging to manage and requires regular screening for potential cancer development.
Lichen planus (LP) presents with a range of clinical subtypes. It can affect the outer skin, involve the nails and present with alopecia and mucosal symptoms to varying degrees. LP of the outer skin mostly shows a self-limiting course; however, this is not the case for lichen planopilaris and the mucosa-affecting subtypes. The pathogenesis of LP is still incompletely understood. As a result, an effective, targeted therapy is currently lacking and different immunomodulatory approaches are being used in clinical practice. The management of patients with severe oral LP mucosae can be particularly challenging. Although the true risk remains controversial, oral LP is considered a risk factor for the development of squamous cell carcinoma and there is a need for regular screening. The quality of life in patients with LP is significantly impaired because of frequent clinical visits, pain, soreness, inability to eat certain foods, side effects to medication, frustrating therapy attempts and worry regarding cancer risk. We highlight here the advantages of an interdisciplinary dermatology and oral surgery clinic, which can address the domains of tooth status, nutrition, pain and malignant transformation and optimized patient management.

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