Charge transfer complex enabled photoreduction of ether phosphonium salts for the selective oxyalkylation of enamides

A charge transfer complex (CTC)-enabled photoreduction of ether phosphonium salts for the generation of oxyalkyl radicals was described. The photoreduction provides a convenient method to achieve selective oxyalkylation of enamides with broad substrate scope. The method features operational simplicity, mild and inherent green conditions.(c) 2023 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

Automated summary

A charge transfer complex (CTC)-enabled photoreduction of ether phosphonium salts for the generation of oxyalkyl radicals was introduced. The method provides a convenient way to achieve selective oxyalkylation of enamides with broad substrate scope. It features operational simplicity, mild and inherent green conditions.