Recent Updates on the Antimicrobial Compounds from Marine-Derived Penicillium fungi

In this review, 72 compounds isolated from marine-derived Penicillium fungi and their antimicrobial activities are reviewed from 2020 to 2023. According to their structures, these compounds can be divided into terpenoids, polyketides, alkaloids and other structural compounds, among which terpenoids and polyketides are relatively large in number. Some compounds have powerful inhibitory effects against different pathogenic bacteria and fungi. This review aims to provide more useful information and enlightenment for further efficient utilization of Penicillium spp. and their secondary metabolites.

Automated summary

This review summarizes 72 compounds isolated from marine-derived Penicillium fungi and their antimicrobial activities from 2020 to 2023. These compounds can be categorized into terpenoids, polyketides, alkaloids, and other structural compounds, with terpenoids and polyketides being the most abundant. Some of these compounds exhibit potent inhibitory effects against various pathogenic bacteria and fungi. The aim of this review is to provide valuable information and insights for the efficient utilization of Penicillium spp. and their secondary metabolites.