4.5 Article

Extraction of Functional Compounds from Tarragon (Artemisia dracunculus L.) by Deep Eutectic Solvents at Different Properties

Journal

CHEMISTRY & BIODIVERSITY
Volume -, Issue -, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.202300417

Keywords

Tarragon; deep eutectic solvents; extraction; bioactive compound; antimicrobial activity

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This study aimed to investigate the extraction ability of deep eutectic solvents (DESs) with different concentrations in obtaining bioactive compounds from tarragon plants. The results showed that DES10 had the highest efficiency in extracting individual phenolics and amino acids, and also yielded higher compared to ethanol and methanol. The total phenolic content, total flavonoid content, and antioxidant activity of DES extracts varied within a certain range. Therefore, the use of these environmentally friendly green solvents can be recommended as an alternative to organic solvents in the extraction process of this important medicinal plant in different areas.
In this study, it was aimed to examine the capacity of deep eutectic solvents (DESs) with different contents to extract bioactive compounds from tarragon (Artemisia dracunculus L.) plant. For this reason, the total phenolic-flavonoid content, total proanthocyanidin content and antioxidant/antimicrobial activities of the prepared DES extracts were investigated, as well as the individual phenolic and individual amino acid profiles. According to the results, DES10 had the highest efficiency in terms of its capacity to extract individual phenolics (approximately 59 mg/100 g) and individual amino acids (approximately 2500 mg/kg), and also gave a higher yield compared to ethanol (approximately 44 mg/100 g for individual phenolics and about 19810 mg/kg for individual amino acids) and methanol (approximately 58 mg/100 g for individual phenolics and approximately 21430 mg/kg for individual amino acids). However, the total phenolic content, total flavonoid content and antioxidant activity values of DES extracts were determined between 59.09-77.50 mg GAE/100 g, 28.68-45.55 mg GAE/100 g and 42.96-146.86 mg TE/100 g, respectively. Therefore, it can be recommended to use these green solvents, which are known as environmentally friendly, as an alternative to organic solvents in the process of preparing extracts of this important medicinal plant in different areas.

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