4.8 Review

Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management

Journal

CHEMICAL REVIEWS
Volume 123, Issue 19, Pages 11488-11558

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.chemrev.3c00290

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This review article introduces the eye as a complex network of physiological information and biomarkers, and discusses the application of ocular devices in disease diagnosis and management. The article also mentions the latest technologies and trends in ocular devices, especially the use of smart contact lenses.
The eye contains a complex network of physiological information and biomarkers for monitoring disease and managing health, and ocular devices can be used to effectively perform point-of-care diagnosis and disease management. This comprehensive review describes the target biomarkers and various diseases, including ophthalmic diseases, metabolic diseases, and neurological diseases, based on the physiological and anatomical background of the eye. This review also includes the recent technologies utilized in eye-wearable medical devices and the latest trends in wearable ophthalmic devices, specifically smart contact lenses for the purpose of disease management. After introducing other ocular devices such as the retinal prosthesis, we further discuss the current challenges and potential possibilities of smart contact lenses.

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