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Pulmonary Surfactant: A Mighty Thin Film

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Jose Carlos Castillo-Sanchez et al.

Summary: This review examines the complex structure-function relationships of lung surfactant, detailing lipid-protein interactions and membrane structures. It highlights the dynamic nature of surfactant function, emphasizing the need for a comprehensive understanding of its molecular mechanisms in vivo.

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FRONTIERS IN IMMUNOLOGY (2021)

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The Miracles of Surfactant: Less Invasive Surfactant Administration, Nebulization, and Carrier of Topical Drugs

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Summary: Surfactant replacement therapy has become the standard of care in neonatal respiratory distress syndrome, but further improvement is needed to reduce the impact of bronchopulmonary dysplasia in extremely immature preterm infants.

NEONATOLOGY (2021)

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Role of pulmonary surfactant protein Sp-C dimerization on membrane fragmentation: An emergent mechanism involved in lung defense and homeostasis

Alejandro Barriga et al.

Summary: This article discusses the dual role of surfactant protein C (SP-C) in the pulmonary surfactant system, both in biophysical properties and lung defense. Results indicate that SP-C oligomerization may trigger membrane budding and nanovesiculation, leading to the presentation of different ligands to lung cells. Vesicles induced by SP-C are differentially assimilated by alveolar macrophages and alveolar type II cells, suggesting distinct roles of these cells in processing the vesicles. These findings provide insights into pulmonary pathologies and potential therapeutic approaches.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2021)

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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2021)

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Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions

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FRONTIERS IN IMMUNOLOGY (2021)

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Surfactant protein C mutation links postnatal type 2 cell dysfunction to adult disease

Sneha Sitaraman et al.

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JCI INSIGHT (2021)

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Article Biochemistry & Molecular Biology

Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2

Raquel Arroyo et al.

Summary: SARS-CoV-2 infection of host cells is driven by the binding of the virus spike protein to lung cells, and the study aims to measure pulmonary SP-D levels in COVID-19 patients and demonstrate its activity against the virus. Results show that SP-D can bind to the SARS-CoV-2 spike protein, initiate aggregation, and inhibit viral replication in cells.

BIOMOLECULES (2021)

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Article Toxicology

An adverse outcome pathway for lung surfactant function inhibition leading to decreased lung function

Emilie Da Silva et al.

Summary: Inhaled substances can inhibit lung surfactant function, leading to decreased lung function. Key events in this process include alveolar collapse and blood components entering the alveolar airspace.

CURRENT RESEARCH IN TOXICOLOGY (2021)

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Article Chemistry, Physical

Superwetting charged copper foams with long permeation channels for ultrafast emulsion separation and surfactant removal

Jihao Zuo et al.

Summary: The study focused on developing superwetting positively and negatively charged copper foams with long permeation channels for ultrafast separation of oil-in-water emulsions and removal of surfactants. The positively charged foam achieved a separation efficiency of up to 99.64% and a permeation flux of up to 22,636.56 L m(-2) h(-1), while the negatively charged foam achieved a separation efficiency of up to 99.65% and a permeation flux of up to 32,166.32 L m(-2) h(-1). The charged copper foams showed efficient removal ability towards anionic and cationic surfactants, making them a promising candidate for oil/water emulsion separation and surfactant removal.

JOURNAL OF MATERIALS CHEMISTRY A (2021)

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Article Chemistry, Physical

Changes in membrane elasticity caused by the hydrophobic surfactant proteins correlate poorly with adsorption of lipid vesicles

Ryan W. Loney et al.

Summary: Our study found that proteins have different effects on lipid chains and lipid bilayers, producing varied outcomes during adsorption processes. While proteins increased the adsorption rate for both lipids, the correlation with changes in lipid chains and bilayers was not strong.

SOFT MATTER (2021)

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Article Physiology

Impact of synthetic surfactant CHF5633 with SP-B and SP-C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome

Pavol Mikolka et al.

Summary: The study compared the treatment effects of synthetic surfactant CHF5633 and animal-derived surfactant poractant alfa in experimental ARDS, finding that both preparations significantly improved lung function and reduced inflammation to similar degrees in the animal model.

PHYSIOLOGICAL REPORTS (2021)

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Article Respiratory System

Surfactant therapy for COVID-19 related ARDS: a retrospective case-control pilot study

Simone Piva et al.

Summary: The study demonstrates that surfactant delivery through bronchoscopy at a dose of 720 mg in 150 ml normal saline is feasible and safe for COVID-19 ARDS patients. Surfactant administration did not cause acute decompensation, may reduce mortality and mechanical ventilation duration in COVID-19 ARDS patients. This supports the need for future randomized clinical trials to evaluate the efficacy of meticulous sub-bronchial lavage with surfactant for COVID-19 ARDS patients.

RESPIRATORY RESEARCH (2021)

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Article Biochemistry & Molecular Biology

Air Space Distension Precedes Spontaneous Fibrotic Remodeling and Impaired Cholesterol Metabolism in the Absence of Surfactant Protein C

Jannik Ruwisch et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)

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Article Pediatrics

Two-year outcome data suggest that less invasive surfactant administration (LISA) is safe. Results from the follow-up of the randomized controlled AMV (avoid mechanical ventilation) study

Egbert Herting et al.

EUROPEAN JOURNAL OF PEDIATRICS (2020)

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Article Biochemistry & Molecular Biology

Pulmonary Surfactant Lipid Reorganization Induced by the Adsorption of the Oligomeric Surfactant Protein B Complex

Juho Liekkinen et al.

JOURNAL OF MOLECULAR BIOLOGY (2020)

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Article Chemistry, Multidisciplinary

Supported Lipid Bilayer Formation: Beyond Vesicle Fusion

Joshua A. Jackman et al.

LANGMUIR (2020)

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Article Critical Care Medicine

Clinical Characteristics, Major Morbidity, and Mortality in Trauma-Related Pediatric Acute Respiratory Distress Syndrome*

Alison B. Nair et al.

PEDIATRIC CRITICAL CARE MEDICINE (2020)

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Article Critical Care Medicine

REGULATORY ROLES OF HUMAN SURFACTANT PROTEIN B VARIANTS ON GENETIC SUSCEPTIBILITY TO PSEUDOMONAS AERUGINOSA PNEUMONIA-INDUCED SEPSIS

Fengyong Yang et al.

SHOCK (2020)

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Article Physiology

Structure and activity of human surfactant protein D from different natural sources

Raquel Arroyo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2020)

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Article Biochemistry & Molecular Biology

Surfactant Injury in the Early Phase of Severe Meconium Aspiration Syndrome

Chiara Autilio et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)

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Article Respiratory System

Surfactant protein A as a biomarker of outcomes of anti-fibrotic drug therapy in patients with idiopathic pulmonary fibrosis

Takumi Yoshikawa et al.

BMC PULMONARY MEDICINE (2020)

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Article Immunology

Generation of novel trimeric fragments of human SP-A and SP-D after recombinant soluble expression in E. coli

Alastair Watson et al.

IMMUNOBIOLOGY (2020)

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Review Biochemistry & Molecular Biology

On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx

Matthias Ochs et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Review Biochemistry & Molecular Biology

Lipid-Protein and Protein-Protein Interactions in the Pulmonary Surfactant System and Their Role in Lung Homeostasis

Olga Canadas et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Review Physiology

Alveolar Dynamics and Beyond - The Importance of Surfactant Protein C and Cholesterol in Lung Homeostasis and Fibrosis

Kirsten Sehlmeyer et al.

FRONTIERS IN PHYSIOLOGY (2020)

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Review Cell Biology

Recent progress on surfactant protein A: cellular function in lung and kidney disease development

Skylar D. King et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2020)

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Article Biochemistry & Molecular Biology

Pulmonary surfactant protein SP-B nanorings induce the multilamellar organization of surfactant complexes

Marta Martinez-Calle et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)

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Article Biophysics

Atomic Force Microscopy Imaging of Adsorbed Pulmonary Surfactant Films

Lu Xu et al.

BIOPHYSICAL JOURNAL (2020)

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Article Biochemistry & Molecular Biology

Mechanical stretch activates piezo1 in caveolae of alveolar type I cells to trigger ATP release and paracrine stimulation of surfactant secretion from alveolar type II cells

Kathrin Diem et al.

FASEB JOURNAL (2020)

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Article Immunology

A 20-Mer Peptide Derived from the Lectin Domain of SP-A2 Decreases Tumor Necrosis Factor Alpha Production during Mycoplasma pneumoniae Infection

Usir S. Younis et al.

INFECTION AND IMMUNITY (2020)

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Review Critical Care Medicine

Emerging pharmacological therapies for ARDS: COVID-19 and beyond

Shahd Horie et al.

INTENSIVE CARE MEDICINE (2020)

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Article Physiology

Three Alveolar Phenotypes Govern Lung Function in Murine Ventilator-Induced Lung Injury

Bradford J. Smith et al.

FRONTIERS IN PHYSIOLOGY (2020)

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Article Pharmacology & Pharmacy

Protective effects of aerosolized pulmonary surfactant powder in a model of ventilator-induced lung injury

Derek Daniher et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pediatrics

Synthetic Surfactant CHF5633 Compared with Poractant Alfa in the Treatment of Neonatal Respiratory Distress Syndrome: A Multicenter, Double-Blind, Randomized, Controlled Clinical Trial

Rangasamy Ramanathan et al.

JOURNAL OF PEDIATRICS (2020)

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Article Chemistry, Physical

Location of the Hydrophobic Surfactant Proteins, SP-B and SP-C, in Fluid-Phase Bilayers

Ryan W. Loney et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2020)

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Editorial Material Critical Care Medicine

Biological Mechanisms of COVID-19 Acute Respiratory Distress Syndrome

Michael A. Matthay et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)

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Review Biochemistry & Molecular Biology

Alveolar lipids in pulmonary disease. A review

Christina W. Agudelo et al.

LIPIDS IN HEALTH AND DISEASE (2020)

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Review Allergy

Pulmonary Surfactants: a New Therapeutic Target in Asthma

Youngwoo Choi et al.

CURRENT ALLERGY AND ASTHMA REPORTS (2020)

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Article Multidisciplinary Sciences

A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency

Martin H. Kang et al.

NATURE COMMUNICATIONS (2020)

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Review Medicine, Research & Experimental

Contributions of alveolar epithelial cell quality control to pulmonary fibrosis

Jeremy Katzen et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

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Article Chemistry, Multidisciplinary

Structural Changes in Films of Pulmonary Surfactant Induced by Surfactant Vesicles

Konstantin Andreev et al.

LANGMUIR (2020)

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Article Pediatrics

Rescue of respiratory failure in pulmonary alveolar proteinosis due to pathogenic MARS1 variants

Dominic Lenz et al.

PEDIATRIC PULMONOLOGY (2020)

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Article Pediatrics

Aerosolized Calfactant for Newborns With Respiratory Distress: A Randomized Trial

James J. Cummings et al.

PEDIATRICS (2020)

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Review Chemistry, Multidisciplinary

Airborne Transmission of COVID-19: Aerosol Dispersion, Lung Deposition, and Virus-Receptor Interactions

Yi Y. Zuo et al.

ACS NANO (2020)

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Article Forestry

Dynamic surface tension of xylem sap lipids

Jinlong Yang et al.

TREE PHYSIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Utility of temporal profiles of new cardio-renal and pulmonary candidate biomarkers in chronic heart failure

Milos Brankovic et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

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Article Pharmacology & Pharmacy

New insights into exogenous surfactant as a carrier of pulmonary therapeutics

Brandon Baer et al.

BIOCHEMICAL PHARMACOLOGY (2019)

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Review Pediatrics

Genetic causes of surfactant protein abnormalities

Lawrence M. Nogee

CURRENT OPINION IN PEDIATRICS (2019)

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Review Biochemistry & Molecular Biology

Phospholipid regulation of innate immunity and respiratory viral infection

Dennis R. Voelker et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

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Article Chemistry, Physical

Determining the surface dilational rheology of surfactant and protein films with a droplet waveform generator

Jinlong Yang et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

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Article Immunology

Epithelial Expression of an Interstitial Lung Disease-Associated Mutation in Surfactant Protein-C Modulates Recruitment and Activation of Key Myeloid Cell Populations in Mice

Alessandro Venosa et al.

JOURNAL OF IMMUNOLOGY (2019)

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Article Chemistry, Multidisciplinary

Poly(amidoamine) Dendrimer as a Respiratory Nanocarrier: Insights from Experiments and Molecular Dynamics Simulations

Fujia Tian et al.

LANGMUIR (2019)

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Editorial Material Respiratory System

Advances in synthetic lung surfactant protein technology

Frans J. Walther et al.

EXPERT REVIEW OF RESPIRATORY MEDICINE (2019)

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Article Medicine, General & Internal

Pulmonary alveolar proteinosis

Bruce C. Trapnell et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

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Article Medicine, General & Internal

Acute respiratory distress syndrome

Michael A. Matthay et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

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Review Genetics & Heredity

Systematic Review and Meta-Analysis Confirms Significant Contribution of Surfactant Protein D in Chronic Obstructive Pulmonary Disease

Debparna Nandy et al.

FRONTIERS IN GENETICS (2019)

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Review Biochemistry & Molecular Biology

Soluble defense collagens: Sweeping up immune threats

Cristina Casals et al.

MOLECULAR IMMUNOLOGY (2019)

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Review Respiratory System

Lung morphology and surfactant function in cardiogenic pulmonary edema: a narrative review

Kenneth Nugent et al.

JOURNAL OF THORACIC DISEASE (2019)

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Article Biophysics

Adsorption of Phospholipids at the Air-Water Surface

Xuan Bai et al.

BIOPHYSICAL JOURNAL (2019)

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Article Medicine, General & Internal

Bronchopulmonary dysplasia

Bernard Thebaud et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

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Article Critical Care Medicine

Lung Repair and Regeneration in ARDS Role of PECAM1 and Wnt Signaling

Jesus Villar et al.

CHEST (2019)

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Review Immunology

Surfactant Proteins A and D: Trimerized Innate Immunity Proteins with an Affinity for Viral Fusion Proteins

Alastair Watson et al.

JOURNAL OF INNATE IMMUNITY (2019)

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Review Medicine, General & Internal

Synthetic surfactants with SP-B and SP-C analogues to enable worldwide treatment of neonatal respiratory distress syndrome and other lung diseases

J. Johansson et al.

JOURNAL OF INTERNAL MEDICINE (2019)

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Review Physiology

BUILDING AND REGENERATING THE LUNG CELL BY CELL

Jeffrey A. Whitsett et al.

PHYSIOLOGICAL REVIEWS (2019)

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Article Multidisciplinary Sciences

Change of surfactant protein D and A after renal ischemia reperfusion injury

Islam Md Imtiazul et al.

PLOS ONE (2019)

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Article Physiology

Surfactant plus budesonide decreases lung and systemic inflammation in mechanically ventilated preterm sheep

T. Brett Kothe et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)

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Review Physiology

Extracellular vesicles in lung health, disease, and therapy

Mark J. McVey et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)

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Article Medicine, Research & Experimental

An SFTPC BRICHOS mutant links epithelial ER stress and spontaneous lung fibrosis

Jeremy Katzen et al.

JCI INSIGHT (2019)

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Review Urology & Nephrology

Collectins in urinary tract and kidney diseases

Yongfang Qin et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2018)

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Article Multidisciplinary Sciences

Interfacial curvature effects on the monolayer morphology and dynamics of a clinical lung surfactant

Amit Kumar Sachan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

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Article Environmental Sciences

Oxygen content determines the bio-reactivity and toxicity profiles of carbon black particles

Yakun Wu et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2018)

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Article Engineering, Environmental

Aggregation State of Metal-Based Nanomaterials at the Pulmonary Surfactant Film Determines Biophysical Inhibition

Yi Yang et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2018)

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Article Biochemistry & Molecular Biology

Pulmonary surfactant protein SP-B promotes exocytosis of lamellar bodies in alveolar type II cells

Marta Martinez-Calle et al.

FASEB JOURNAL (2018)

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Review Medicine, General & Internal

Acute Respiratory Distress Syndrome Advances in Diagnosis and Treatment

Eddy Fan et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

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Article Biochemistry & Molecular Biology

Homo- and hetero-oligomerization of hydrophobic pulmonary surfactant proteins SP-B and SP-C in surfactant phospholipid membranes

Elisa J. Cabre et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

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Article Chemistry, Multidisciplinary

The Lγ Phase of Pulmonary Surfactant

Kamlesh Kumar et al.

LANGMUIR (2018)

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Article Chemistry, Multidisciplinary

Droplet Oscillation as an Arbitrary Waveform Generator

Kyle Yu et al.

LANGMUIR (2018)

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Article Chemistry, Multidisciplinary

Melting of the Dipalmitoylphosphatidylcholine Monolayer

Lu Xu et al.

LANGMUIR (2018)

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Article Chemistry, Multidisciplinary

Reversible Phase Transitions in the Phospholipid Monolayer

Lu Xu et al.

LANGMUIR (2018)

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Article Chemistry, Multidisciplinary

Role of Lipid Coating in the Transport of Nanodroplets across the Pulmonary Surfactant Layer Revealed by Molecular Dynamics Simulations

Yan Xu et al.

LANGMUIR (2018)

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Article Medicine, General & Internal

Surfactant Dysfunction in ARDS and Bronchiolitis is Repaired with Cyclodextrins

Mustafa Al-Saiedy et al.

MILITARY MEDICINE (2018)

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Article Multidisciplinary Sciences

Controlled hypothermia may improve surfactant function in asphyxiated neonates with or without meconium aspiration syndrome

Chiara Autilio et al.

PLOS ONE (2018)

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Article Physiology

Surfactant proteins changes after acute hemodynamic improvement in patients with advanced chronic heart failure treated with Levosimendan

Jeness Campodonico et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2018)

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Article Medicine, Research & Experimental

Prediction of Acute Inhalation Toxicity Using In Vitro Lung Surfactant Inhibition

Jorid B. Sorli et al.

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2018)

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Article Multidisciplinary Sciences

Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Ann M. Czyzewski et al.

SCIENTIFIC REPORTS (2018)

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Article Materials Science, Biomaterials

Tuning protein assembly pathways through superfast amyloid-like aggregation

Chen Li et al.

BIOMATERIALS SCIENCE (2018)

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Article Chemistry, Multidisciplinary

Nanoparticle-induced structural changes in lung surfactant membranes: an X-ray scattering study

Shirin Behyan et al.

ENVIRONMENTAL SCIENCE-NANO (2018)

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Review Immunology

The Role and Molecular Mechanism of Action of Surfactant Protein D in Innate Host Defense Against Influenza A Virus

I-Ni Hsieh et al.

FRONTIERS IN IMMUNOLOGY (2018)

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Review Biochemistry & Molecular Biology

Rab38 Mutation and the Lung Phenotype

Kazuhiro Osanai

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

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Article Biochemistry & Molecular Biology

Metabolism of a synthetic compared with a natural therapeutic pulmonary surfactant in adult mice

Jens Madsen et al.

JOURNAL OF LIPID RESEARCH (2018)

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Review Immunology

The Role of Collectins and Galectins in Lung Innate Immune Defense

Cristina Casals et al.

FRONTIERS IN IMMUNOLOGY (2018)

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Article Chemistry, Multidisciplinary

Pulmonary surfactant and drug delivery: Focusing on the role of surfactant proteins

Roberta Guagliardo et al.

JOURNAL OF CONTROLLED RELEASE (2018)

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Article Immunology

Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

Zhenwu Lin et al.

FRONTIERS IN IMMUNOLOGY (2018)

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Article Chemistry, Physical

Biophysical Assessment of Pulmonary Surfactant Predicts the Lung Toxicity of Nanomaterials

Yi Yang et al.

SMALL METHODS (2018)

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Article Nursing

Prevention and Treatment of Respiratory Distress Syndrome in Preterm Neonates

Christopher McPherson et al.

NEONATAL NETWORK (2018)

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Review Cell Biology

The biology of the ABCA3 lipid transporter in lung health and disease

Michael F. Beers et al.

CELL AND TISSUE RESEARCH (2017)

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Review Immunology

Non-Pulmonary Immune Functions of Surfactant Proteins A and D

Sylvia Ujma et al.

JOURNAL OF INNATE IMMUNITY (2017)

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Article Plant Sciences

Xylem Surfactants Introduce a New Element to the Cohesion-Tension Theory

H. Jochen Schenk et al.

PLANT PHYSIOLOGY (2017)

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Article Respiratory System

Pulmonary surfactant dysfunction in pediatric cystic fibrosis: Mechanisms and reversal with a lipid-sequestering drug

Lasantha Gunasekara et al.

JOURNAL OF CYSTIC FIBROSIS (2017)

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Article Environmental Sciences

Mesoporous carbon nanomaterials induced pulmonary surfactant inhibition, cytotoxicity, inflammation and lung fibrosis

Yunan Chen et al.

JOURNAL OF ENVIRONMENTAL SCIENCES (2017)

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Article Cardiac & Cardiovascular Systems

Lung lavage and Surfactant Replacement During Ex Vivo Lung Perfusion for Treatment of Gastric Acid Aspiration-Induced Donor Lung Injury

Daisuke Nakajima et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2017)

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Article Chemistry, Physical

Entropic Anomaly Observed in Lipid Polymorphisms Induced by Surfactant Peptide SP-B(1-25)

Nhi Tran et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2017)

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Article Chemistry, Multidisciplinary

Accuracy of Axisymmetric Drop Shape Analysis in Determining Surface and Interfacial Tensions

Jinlong Yang et al.

LANGMUIR (2017)

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Article Oncology

Correlation analysis of surfactant protein A and surfactant protein D with lung function in exhaled breath condensate from lung cancer patients with and without COPD

Xuefeng Lin et al.

MOLECULAR MEDICINE REPORTS (2017)

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Article Medicine, Research & Experimental

Alveolar injury and regeneration following deletion of ABCA3

Tara N. Rindler et al.

JCI INSIGHT (2017)

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Article Anatomy & Morphology

Pulmonary surfactant metabolism in the alveolar airspace: Biogenesis, extracellular conversions, recycling

Barbara Olmeda et al.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2017)

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Article Pediatrics

A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome

David G. Sweet et al.

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION (2017)

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Article Biochemistry & Molecular Biology

Restoring pulmonary surfactant membranes and films at the respiratory surface

Mercedes Echaide et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)

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Article Biochemistry & Molecular Biology

Differential Ligand Binding Specificities of the Pulmonary Collectins Are Determined by the Conformational Freedom of a Surface Loop

Michael J. Rynkiewicz et al.

BIOCHEMISTRY (2017)

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Article Biophysics

Divide & Conquer: Surfactant Protein SP-C and Cholesterol Modulate Phase Segregation in Lung Surfactant

Nuria Roldan et al.

BIOPHYSICAL JOURNAL (2017)

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Article Biochemistry & Molecular Biology

The role of multilayers in preventing the premature buckling of the pulmonary surfactant

Mustafa Al-Saiedy et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)

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Article Chemistry, Multidisciplinary

Unveiling the Molecular Structure of Pulmonary Surfactant Corona on Nanoparticles

Qinglin Hu et al.

ACS NANO (2017)

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Meeting Abstract Biophysics

Delivery of Lung Surfactant SP-C Based Nanostructures to Respiratory Air-Liquid Interfacial Films

Nuria Roldan et al.

BIOPHYSICAL JOURNAL (2017)

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Article Medicine, Research & Experimental

Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling

Kari Brown et al.

JCI INSIGHT (2017)

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Letter Critical Care Medicine

Did Reduced Alveolar Delivery of Surfactant Contribute to Negative Results in Adults with Acute Respiratory Distress Syndrome?

James B. Grotberg et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)

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Review Respiratory System

Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation

Amanda B. Chai et al.

RESPIRATORY RESEARCH (2017)

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Article Biochemistry & Molecular Biology

Structural characterization in mixed lipid membrane systems by neutron and X-ray scattering

Mikhail A. Kiselev et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2017)

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Article Physiology

Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo

Elena Lopez-Rodriguez et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)

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Article Biochemistry & Molecular Biology

Differential susceptibility of transgenic mice expressing human surfactant protein B genetic variants to Pseudomonas aeruginosa induced pneumonia

Lin Ge et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

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Article Biochemistry & Molecular Biology

Computer simulations of lung surfactant

Svetlana Baoukina et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)

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Article Biochemistry & Molecular Biology

A small key unlocks a heavy door: The essential function of the small hydrophobic proteins SP-B and SP-C to trigger adsorption of pulmonary surfactant lamellar bodies

Nina Hobi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)

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Article Biophysics

Understanding the formation of supported lipid bilayers via vesicle fusion-A case that exemplifies the need for the complementary method approach (Review)

Tania K. Lind et al.

BIOINTERPHASES (2016)

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Article Biophysics

Effect of Lung Surfactant Protein SP-C and SP-C-Promoted Membrane Fragmentation on Cholesterol Dynamics

Nuria Roldan et al.

BIOPHYSICAL JOURNAL (2016)

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Article Biophysics

Experimental Estimation of Membrane Tension Induced by Osmotic Pressure

Sayed Ul Alam Shibly et al.

BIOPHYSICAL JOURNAL (2016)

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Article Immunology

Surfactant protein D induces immune quiescence and apoptosis of mitogen-activated peripheral blood mononuclear cells

Hrishikesh Pandit et al.

IMMUNOBIOLOGY (2016)

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Article Medicine, General & Internal

Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries

Giacomo Bellani et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

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Article Chemistry, Physical

Liquid Surface X-ray Studies of Gold Nanoparticle-Phospholipid Films at the Air/Water Interface

Siheng Sean You et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2016)

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Article Chemistry, Multidisciplinary

Effect of an Anionic Lipid on the Barotropic Behavior of a Ternary Bicellar Mixture

Collin Knight et al.

LANGMUIR (2016)

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Article Chemistry, Multidisciplinary

Phase Transitions in Dipalmitoylphosphatidylcholine Monolayers

Yi Y. Zuo et al.

LANGMUIR (2016)

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Article Chemistry, Multidisciplinary

Automated Droplet Manipulation Using Closed-Loop Axisymmetric Drop Shape Analysis

Kyle Yu et al.

LANGMUIR (2016)

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Article Pediatrics

Neonatal Respiratory Diseases in the Newborn Infant: Novel Insights from Stable Isotope Tracer Studies

Virgilio P. Carnielli et al.

NEONATOLOGY (2016)

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Article Critical Care Medicine

DIFFERENTIAL SUSCEPTIBILITY OF HUMAN SP-B GENETIC VARIANTS ON LUNG INJURY CAUSED BY BACTERIAL PNEUMONIA AND THE EFFECT OF A CHEMICALLY MODIFIED CURCUMIN

Yongan Xu et al.

SHOCK (2016)

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Review Immunology

The Intracellular Cholesterol Landscape: Dynamic Integrator of the Immune Response

Michael B. Fessler

TRENDS IN IMMUNOLOGY (2016)

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Article Biophysics

Understanding the formation of supported lipid bilayers via vesicle fusion-A case that exemplifies the need for the complementary method approach (Review)

Tania K. Lind et al.

BIOINTERPHASES (2016)

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Article Multidisciplinary Sciences

Synthetic lung surfactants containing SP-B and SP-C peptides plus novel phospholipase-resistant lipids or glycerophospholipids

Robert H. Notter et al.

PEERJ (2016)

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Article Physiology

Evolution, Development, and Function of the Pulmonary Surfactant System in Normal and Perturbed Environments

Sandra Orgeig et al.

COMPREHENSIVE PHYSIOLOGY (2016)

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Article Chemistry, Multidisciplinary

Biophysical Influence of Airborne Carbon Nanomaterials on Natural Pulmonary Surfactant

Russell P. Valle et al.

ACS NANO (2015)

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Article Physiology

A non-BRICHOS SFTPC mutant (SP-C-I73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and mitophagy

Arie Hawkins et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)

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Review Pathology

Diseases of Pulmonary Surfactant Homeostasis

Jeffrey A. Whitsett et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 (2015)

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Article Microbiology

Antimicrobial and Biophysical Properties of Surfactant Supplemented with an Antimicrobial Peptide for Treatment of Bacterial Pneumonia

Brandon J. H. Banaschewski et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)

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Article Biochemistry & Molecular Biology

Palmitoylation as a key factor to modulate SP-C-lipid interactions in lung surfactant membrane multilayers

Nuria Roldan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)

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Article Biochemistry & Molecular Biology

Cholesterol-mediated surfactant dysfunction is mitigated by surfactant protein A

Joshua Qua Hiansen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)

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Article Biophysics

Pneumocytes Assemble Lung Surfactant as Highly Packed/Dehydrated States with Optimal Surface Activity

Alejandro Cerrada et al.

BIOPHYSICAL JOURNAL (2015)

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Article Biophysics

Hydrophobic Surfactant Proteins Strongly Induce Negative Curvature

Mariya Chavarha et al.

BIOPHYSICAL JOURNAL (2015)

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Review Biochemistry & Molecular Biology

Composition, structure and mechanical properties define performance of pulmonary surfactant membranes and films

Elisa Parra et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2015)

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Article Biochemistry & Molecular Biology

A model for the structure and mechanism of action of pulmonary surfactant protein B

Barbara Olmeda et al.

FASEB JOURNAL (2015)

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Article Cardiac & Cardiovascular Systems

Plasma immature form of surfactant protein type B correlates with prognosis in patients with chronic heart failure. A pilot single-center prospective study

Damiano Magri et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)

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Article Biochemistry & Molecular Biology

Folding and Intramembraneous BRICHOS Binding of the Prosurfactant Protein C Transmembrane Segment

Alejandra Saenz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

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Article Immunology

Natural Anti-Infective Pulmonary Proteins: In Vivo Cooperative Action of Surfactant Protein SP-A and the Lung Antimicrobial Peptide SP-BN

Juan Manuel Coya et al.

JOURNAL OF IMMUNOLOGY (2015)

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Article Chemistry, Multidisciplinary

Detailed Analysis of the Surface Area and Elasticity in the Saturated 1,2-Diacylphosphatidylcholine/Cholesterol Binary Monolayer System

Tsubasa Miyoshi et al.

LANGMUIR (2015)

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Editorial Material Pediatrics

30 Years of Surfactant Research - From Basic Science to New Clinical Treatments for the Preterm Infant

Tore Curstedt et al.

NEONATOLOGY (2015)

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Article Pediatrics

Lung development

Dhanya Mullassery et al.

SEMINARS IN PEDIATRIC SURGERY (2015)

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Article Multidisciplinary Sciences

Direct visualization of dispersed lipid bicontinuous cubic phases by cryo-electron tomography

Davide Demurtas et al.

NATURE COMMUNICATIONS (2015)

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Review Medicine, General & Internal

Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants

Neetu Singh et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2015)

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Review Respiratory System

The Role of Surfactant in Lung Disease and Host Defense against Pulmonary Infections

SeungHye Han et al.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2015)

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Article Physiology

F-actin scaffold stabilizes lamellar bodies during surfactant secretion

Mohammad N. Islam et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)

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Review Biochemistry & Molecular Biology

Eosinophil-Associated Lung Diseases A Cry for Surfactant Proteins A and D Help?

Julie G. Ledford et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)

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Article Biochemistry & Molecular Biology

A detailed analysis of partial molecular volumes in DPPC/cholesterol binary bilayers

Tsubasa Miyoshi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)

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Article Pediatrics

Natural History of Five Children With Surfactant Protein C Mutations and Interstitial Lung Disease

Avraham Avital et al.

PEDIATRIC PULMONOLOGY (2014)

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Article Pediatrics

Nebulizing Poractant Alfa Versus Conventional Instillation: Ultrastructural Appearance and Preservation of Surface Activity

Stefan Minocchieri et al.

PEDIATRIC PULMONOLOGY (2014)

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Article Multidisciplinary Sciences

Surfactant-Derived Proteins as Markers of Alveolar Membrane Damage in Heart Failure

Paola Gargiulo et al.

PLOS ONE (2014)

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Review Medicine, General & Internal

Childhood asthma: causes, risks, and protective factors; a role of innate immunity

Georgios T. Noutsios et al.

SWISS MEDICAL WEEKLY (2014)

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Article Chemistry, Multidisciplinary

Increasing Hydrophobicity of Nanoparticles Intensifies Lung Surfactant Film Inhibition and Particle Retention

Russell P. Valle et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2014)

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Article Multidisciplinary Sciences

Surfactant protein C peptides with salt-bridges (ion-locks) promote high surfactant activities by mimicking the α-helix and membrane topography of the native protein

Frans J. Walther et al.

PEERJ (2014)

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Article Respiratory System

Altered molecular specificity of surfactant phosphatidycholine synthesis in patients with acute respiratory distress syndrome

Ahilanandan Dushianthan et al.

RESPIRATORY RESEARCH (2014)

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Article Chemistry, Multidisciplinary

Physicochemical Properties of Nanoparticles Regulate Translocation across Pulmonary Surfactant Monolayer and Formation of Lipoprotein Corona

Guoqing Hu et al.

ACS NANO (2013)

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Article Biochemistry & Molecular Biology

Orphan G Protein-Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size

James P. Bridges et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)

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Article Biochemistry & Molecular Biology

Adaptations to hibernation in lung surfactant composition of 13-lined ground squirrels influence surfactant lipid phase segregation properties

Lakshmi N. M. Suri et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)

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Article Biochemistry & Molecular Biology

Compositional and structural characterization of monolayers and bilayers composed of native pulmonary surfactant from wild type mice

Jorge Bernardino de la Serna et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)

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Review Biochemistry & Molecular Biology

Regulation of lung surfactant phospholipid synthesis and metabolism

Victoria Goss et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)

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Article Biophysics

Hydrophobic Pulmonary Surfactant Proteins SP-B and SP-C Induce Pore Formation in Planar Lipid Membranes: Evidence for Proteolipid Pores

Elisa Parra et al.

BIOPHYSICAL JOURNAL (2013)

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Article Endocrinology & Metabolism

Mice Deficient in Surfactant Protein A (SP-A) and SP-D or in TLR2 Manifest Delayed Parturition and Decreased Expression of Inflammatory and Contractile Genes

Alina P. Montalbano et al.

ENDOCRINOLOGY (2013)

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Review Biophysics

Structure-function correlations of pulmonary surfactant protein SP-B and the saposin-like family of proteins

Barbara Olmeda et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2013)

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Article Respiratory System

Hyaluronan with dextran added to therapeutic lung surfactants improves effectiveness in vitro and in vivo

Karen W. Lu et al.

EXPERIMENTAL LUNG RESEARCH (2013)

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Article Chemistry, Physical

Segregated ordered lipid phases and protein-promoted membrane cohesivity are required for pulmonary surfactant films to stabilize and protect the respiratory surface

Jorge Bernardino de la Serna et al.

FARADAY DISCUSSIONS (2013)

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Article Biochemistry & Molecular Biology

Ligands and receptors of lung surfactant proteins SP-A and SP-D

Anne Jakel et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2013)

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Article Biochemistry & Molecular Biology

Transient Exposure of Pulmonary Surfactant to Hyaluronan Promotes Structural and Compositional Transformations into a Highly Active State

Elena Lopez-Rodriguez et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

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Review Biochemistry & Molecular Biology

Linking surfactant protein SP-D and IL-13: Implications in asthma and allergy

Asif S. Qaseem et al.

MOLECULAR IMMUNOLOGY (2013)

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Article Chemistry, Multidisciplinary

Response to Hydrostatic Pressure of Bicellar Dispersions Containing an Anionic Lipid: Pressure-Induced Interdigitation

Ashkan Rahmani et al.

LANGMUIR (2013)

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Article Pediatrics

The Surfactant System Protects Both Fetus and Newborn

Mikko Hallman

NEONATOLOGY (2013)

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Article Pediatrics

New Generation Synthetic Surfactants

Tore Curstedt et al.

NEONATOLOGY (2013)

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Article Critical Care Medicine

Pediatric Calfactant in Acute Respiratory Distress Syndrome Trial

Douglas F. Willson et al.

PEDIATRIC CRITICAL CARE MEDICINE (2013)

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Effect of cholesterol nanodomains on monolayer morphology and dynamics

KyuHan Kim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Article Respiratory System

Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury

Stephan W. Glasser et al.

RESPIRATORY RESEARCH (2013)

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Article Pharmacology & Pharmacy

Emerging roles for cholesterol and lipoproteins in lung disease

Kymberly M. Gowdy et al.

PULMONARY PHARMACOLOGY & THERAPEUTICS (2013)

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Review Immunology

The UPR and lung disease

Fabiola Osorio et al.

SEMINARS IN IMMUNOPATHOLOGY (2013)

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Review Medicine, General & Internal

Surfactant and allergic airway inflammation

Carla Winkler et al.

SWISS MEDICAL WEEKLY (2013)

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Article Respiratory System

Value of serum and induced sputum surfactant protein-D in chronic obstructive pulmonary disease

Berna Akinci Ozyurek et al.

MULTIDISCIPLINARY RESPIRATORY MEDICINE (2013)

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Review Immunology

NET balancing: a problem in inflammatory lung diseases

Olivia Z. Cheng et al.

FRONTIERS IN IMMUNOLOGY (2013)

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New insights of P2X7 receptor signaling pathway in alveolar functions

Amarjit Mishra

JOURNAL OF BIOMEDICAL SCIENCE (2013)

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Article Obstetrics & Gynecology

A Randomized, Controlled Trial of Poractant Alfa versus Beractant in the Treatment of Preterm Infants with Respiratory Distress Syndrome

Evrim Alyamac Dizdar et al.

AMERICAN JOURNAL OF PERINATOLOGY (2012)

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Article Medicine, General & Internal

Secretory Phospholipase A2-Mediated Depletion of Phosphatidylglycerol in Early Acute Respiratory Distress Syndrome

Michael C. Seeds et al.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2012)

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Article Biochemistry & Molecular Biology

Adaptation to low body temperature influences pulmonary surfactant composition thereby increasing fluidity while maintaining appropriately ordered membrane structure and surface activity

Lakshmi N. M. Suri et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

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Article Biochemistry & Molecular Biology

A modified squeeze-out mechanism for generating high surface pressures with pulmonary surfactant

Eleonora Keating et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

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Review Biochemistry & Molecular Biology

Role of lipid ordered/disordered phase coexistence in pulmonary surfactant function

Cristina Casals et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

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Article Pediatrics

Physiology of Transition from Intrauterine to Extrauterine Life

Noah H. Hillman et al.

CLINICS IN PERINATOLOGY (2012)

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Levosimendan: Molecular mechanisms and clinical implications Consensus of experts on the mechanisms of action of levosimendan

Zoltan Papp et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2012)

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Article Medicine, General & Internal

Acute Respiratory Distress Syndrome The Berlin Definition

V. Marco Ranieri et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

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Article Anesthesiology

Exogenous Surfactant May Improve Oxygenation but Not Mortality in Adult Patients with Acute Lung Injury/Acute Respiratory Distress Syndrome: A Meta-Analysis of 9 Clinical Trials

Haoyu Meng et al.

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA (2012)

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Article Chemistry, Multidisciplinary

Differential Effects of the Hydrophobic Surfactant Proteins on the Formation of Inverse Bicontinuous Cubic Phases

Mariya Chavarha et al.

LANGMUIR (2012)

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Article Chemistry, Multidisciplinary

Interfacial Behavior of Recombinant Forms of Human Pulmonary Surfactant Protein SP-C

Dunja Lukovic et al.

LANGMUIR (2012)

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Article Pediatrics

Differential effects of cholesterol and budesonide on biophysical properties of clinical surfactant

Hong Zhang et al.

PEDIATRIC RESEARCH (2012)

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Review Critical Care Medicine

Clinical review: Exogenous surfactant therapy for acute lung injury/acute respiratory distress syndrome - where do we go from here?

Ahilanandan Dushianthan et al.

CRITICAL CARE (2012)

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Article Chemistry, Multidisciplinary

Adverse Biophysical Effects of Hydroxyapatite Nanoparticles on Natural Pulmonary Surfactant

Qihui Fan et al.

ACS NANO (2011)

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Article Education, Scientific Disciplines

Why is surface tension a force parallel to the interface?

Antonin Marchand et al.

AMERICAN JOURNAL OF PHYSICS (2011)

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Editorial Material Critical Care Medicine

Another Negative'' Trial of Surfactant Time to Bury this Idea?

Roy G. Brower et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

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Article Critical Care Medicine

Recombinant Surfactant Protein C-based Surfactant for Patients with Severe Direct Lung Injury

Roger G. Spragg et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

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Article Biochemistry & Molecular Biology

A combined action of pulmonary surfactant proteins SP-B and SP-C modulates permeability and dynamics of phospholipid membranes

Elisa Parra et al.

BIOCHEMICAL JOURNAL (2011)

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Article Biochemistry & Molecular Biology

Phospholipid packing and hydration in pulmonary surfactant membranes and films as sensed by LAURDAN

M. Victoria Picardi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)

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Article Biochemistry & Molecular Biology

A ToF-SIMS study of the lateral organization of lipids and proteins in pulmonary surfactant systems

Eleonora Keating et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)

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Article Biochemistry & Molecular Biology

Comparative study of clinical pulmonary surfactants using atomic force microscopy

Hong Zhang et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)

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Article Biochemistry & Molecular Biology

Atomic force microscopy analysis of rat pulmonary surfactant films

Xiujun Jiao et al.

BIOPHYSICAL CHEMISTRY (2011)

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Article Biophysics

Lung Surfactant Protein SP-B Promotes Formation of Bilayer Reservoirs from Monolayer and Lipid Transfer between the Interface and Subphase

Svetlana Baoukina et al.

BIOPHYSICAL JOURNAL (2011)

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Article Biophysics

Glycerol-Induced Membrane Stiffening: The Role of Viscous Fluid Adlayers

Luka Pocivavsek et al.

BIOPHYSICAL JOURNAL (2011)

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Article Oncology

Serum levels of surfactant protein D predict the anti-tumor activity of gefitinib in patients with advanced non-small cell lung cancer

Hiroyuki Yamaguchi et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)

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Article Critical Care Medicine

Surfactant Therapy for Acute Lung Injury and Acute Respiratory Distress Syndrome

Krishnan Raghavendran et al.

CRITICAL CARE CLINICS (2011)

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Article Critical Care Medicine

The influence of genetic variation in surfactant protein B on severe lung injury in African American children

Mary K. Dahmer et al.

CRITICAL CARE MEDICINE (2011)

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Article Respiratory System

Elevation of surfactant protein A in plasma and sputum in cigarette smokers

W. Mazur et al.

EUROPEAN RESPIRATORY JOURNAL (2011)

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Article Chemistry, Physical

Cholesterol Effect on Water Permeability through DPPC and PSM Lipid Bilayers: A Molecular Dynamics Study

Hiroaki Saito et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2011)

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Article Chemistry, Multidisciplinary

The Accelerated Late Adsorption of Pulmonary Surfactant

Ryan W. Loney et al.

LANGMUIR (2011)

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Article Chemistry, Multidisciplinary

On the Low Surface Tension of Lung Surfactant

Hong Zhang et al.

LANGMUIR (2011)

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Article Pediatrics

Surfactant Dysfunction

W. Adam Gower et al.

PAEDIATRIC RESPIRATORY REVIEWS (2011)

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Review Pediatrics

Neonatal Mortality From Respiratory Distress Syndrome: Lessons for Low-Resource Countries

Beena D. Kamath et al.

PEDIATRICS (2011)

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Article Critical Care Medicine

The Future of Exogenous Surfactant Therapy

Douglas F. Willson et al.

RESPIRATORY CARE (2011)

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Article Respiratory System

Disaturated-phosphatidylcholine and Surfactant protein-B turnover in human acute lung injury and in control patients

Manuela Simonato et al.

RESPIRATORY RESEARCH (2011)

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Article Respiratory System

Comprehensive characterisation of pulmonary and serum surfactant protein D in COPD

Carla Winkler et al.

RESPIRATORY RESEARCH (2011)

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Article Physiology

Matrix modulation of compensatory lung regrowth and progenitor cell proliferation in mice

A. M. Hoffman et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2010)

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Article Critical Care Medicine

Surfactant Protein-D Inhibits Lung Inflammation Caused by Ventilation in Premature Newborn Lambs

Atsuyasu Sato et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)

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Article Biochemistry & Molecular Biology

Methyl-β-cyclodextrin restores the structure and function of pulmonary surfactant films impaired by cholesterol

Lasantha C. Gunasekara et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)

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Review Biochemistry & Molecular Biology

Overcoming rapid inactivation of lung surfactant: Analogies between competitive adsorption and colloid stability

Joseph A. Zasadzinski et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)

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Article Biochemistry & Molecular Biology

Pulmonary surfactant layers accelerate O2 diffusion through the air-water interface

Barbara Olmeda et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)

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Article Biophysics

Hydrophobic Surfactant Proteins Induce a Phosphatidylethanolamine to Form Cubic Phases

Mariya Chavarha et al.

BIOPHYSICAL JOURNAL (2010)

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Article Biophysics

Palmitoylation of Pulmonary Surfactant Protein SP-C Is Critical for Its Functional Cooperation with SP-B to Sustain Compression/Expansion Dynamics in Cholesterol-Containing Surfactant Films

Florian Baumgart et al.

BIOPHYSICAL JOURNAL (2010)

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Article Biophysics

Combined and Independent Action of Proteins SP-B and SP-C in the Surface Behavior and Mechanical Stability of Pulmonary Surfactant Films

David Schuerch et al.

BIOPHYSICAL JOURNAL (2010)

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Lamellar Body Exocytosis by Cell Stretch or Purinergic Stimulation: Possible Physiological Roles, Messengers and Mechanisms

Paul Dietl et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2010)

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Review Cell Biology

The Closer we Look the more we See? Quantitative Microscopic Analysis of the Pulmonary Surfactant System

Matthias Ochs

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2010)

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Review Cell Biology

P63 (CKAP4) as an SP-A Receptor: Implications for Surfactant Turnover

Sandra R. Bates

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2010)

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Review Allergy

SP-D and regulation of the pulmonary innate immune system in allergic airway changes

L. R. Forbes et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2010)

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Article Genetics & Heredity

Respiratory disease in Niemann-Pick type C2 is caused by pulmonary alveolar proteinosis

M. Griese et al.

CLINICAL GENETICS (2010)

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Review Pharmacology & Pharmacy

Pharmacotherapy for Prevention and Treatment of Acute Respiratory Distress Syndrome Current and Experimental Approaches

Karen J. Bosma et al.

DRUGS (2010)

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Article Chemistry, Physical

Lateral pressure profiles in lipid monolayers

Svetlana Baoukina et al.

FARADAY DISCUSSIONS (2010)

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Article Biochemistry & Molecular Biology

Fluidizing effects of C-reactive protein on lung surfactant membranes: protective role of surfactant protein A

Alejandra Saenz et al.

FASEB JOURNAL (2010)

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Article Cell Biology

Lamellar body ultrastructure revisited: high-pressure freezing and cryo-electron microscopy of vitreous sections

Dimitri Vanhecke et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2010)

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Article Immunology

The human lung surfactant proteins A (SP-A) and D (SP-D) interact with apoptotic target cells by different binding mechanisms

Anne Jaekel et al.

IMMUNOBIOLOGY (2010)

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Review Biochemistry & Molecular Biology

Collectins link innate and adaptive immunity in allergic airway disease

Julie G. Ledford et al.

INNATE IMMUNITY (2010)

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Review Biochemistry & Molecular Biology

The intersection of surfactant homeostasis and innate host defense of the lung: lessons from newborn infants

Jeffrey A. Whitsett

INNATE IMMUNITY (2010)

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Review Biochemistry & Molecular Biology

Structural determinants of pattern recognition by lung collectins

Barbara A. Seaton et al.

INNATE IMMUNITY (2010)

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Article Biochemistry & Molecular Biology

Lamellar Bodies Form Solid Three-dimensional Films at the Respiratory Air-Liquid Interface

Andrea Ravasio et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

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Article Cardiac & Cardiovascular Systems

Exogenous surfactant in ischemia/reperfusion: Effects on endogenous surfactant pools

Christian Muehlfeld et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2010)

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Article Immunology

Surfactant Protein B Propeptide Contains a Saposin-Like Protein Domain with Antimicrobial Activity at Low pH

Li Yang et al.

JOURNAL OF IMMUNOLOGY (2010)

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Article Pediatrics

Synthetic Surfactant Based on Analogues of SP-B and SP-C Is Superior to Single-Peptide Surfactants in Ventilated Premature Rabbits

Andreas Almlen et al.

NEONATOLOGY (2010)

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Review Pediatrics

Different Effects of Surfactant Proteins B and C - Implications for Development of Synthetic Surfactants

Tore Curstedt et al.

NEONATOLOGY (2010)

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Review Physiology

Pulmonary Surfactant Pathophysiology: Current Models and Open Questions

Jesus Perez-Gil et al.

PHYSIOLOGY (2010)

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Review Physiology

Recent advances in alveolar biology: Some new looks at the alveolar interface

Fred Possmayer et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2010)

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Article Physiology

Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection

Stephan W. Glasser et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)

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Article Biochemistry & Molecular Biology

Pulmonary Surfactant Surface Tension Influences Alveolar Capillary Shape and Oxygenation

Machiko Ikegami et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)

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Review Biochemistry & Molecular Biology

An introduction to critical points for biophysicists; observations of compositional heterogeneity in lipid membranes

Aurelia R. Honerkamp-Smith et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

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Article Biochemistry & Molecular Biology

Thermotropic and structural evaluation of the interaction of natural sphingomyelins with cholesterol

Peter J. Quinn et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

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Article Biophysics

Pulmonary Surfactant Protein SP-C Counteracts the Deleterious Effects of Cholesterol on the Activity of Surfactant Films under Physiologically Relevant Compression-Expansion Dynamics

Leticia Gomez-Gil et al.

BIOPHYSICAL JOURNAL (2009)

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Article Biophysics

Phase Equilibria in DOPC/DPPC-d62/Cholesterol Mixtures

James H. Davis et al.

BIOPHYSICAL JOURNAL (2009)

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Article Biophysics

Segregated Phases in Pulmonary Surfactant Membranes Do Not Show Coexistence of Lipid Populations with Differentiated Dynamic Properties

Jorge Bernardino de la Serna et al.

BIOPHYSICAL JOURNAL (2009)

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Article Critical Care Medicine

Serum Surfactant Protein-A Is a Strong Predictor of Early Mortality in Idiopathic Pulmonary Fibrosis

Brent W. Kinder et al.

CHEST (2009)

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Article Cardiac & Cardiovascular Systems

Circulating Plasma Surfactant Protein Type B as Biological Marker of Alveolar-Capillary Barrier Damage in Chronic Heart Failure

Damiano Magri et al.

CIRCULATION-HEART FAILURE (2009)

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Article Obstetrics & Gynecology

Pulmonary surfactant kinetics of the newborn infant: novel insights from studies with stable isotopes

V. P. Carnielli et al.

JOURNAL OF PERINATOLOGY (2009)

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Article Pediatrics

Developmental and Genetic Regulation of Human Surfactant Protein B in vivo

Aaron Hamvas et al.

NEONATOLOGY (2009)

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Review Pathology

Genetic Disorders of Surfactant Dysfunction

Susan E. Wert et al.

PEDIATRIC AND DEVELOPMENTAL PATHOLOGY (2009)

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Article Respiratory System

The effect of titanium dioxide nanoparticles on pulmonary surfactant function and ultrastructure

Carsten Schleh et al.

RESPIRATORY RESEARCH (2009)

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Article Pathology

A Mutation in Rab38 Small GTPase Causes Abnormal Lung Surfactant Homeostasis and Aberrant Alveolar Structure in Mice

Kazuhiro Osanai et al.

AMERICAN JOURNAL OF PATHOLOGY (2008)

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Article Physiology

Alterations to surfactant precede physiological deterioration during high tidal volume ventilation

Adam A. Maruscak et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)

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Review Chemistry, Physical

Collapse mechanisms of Langmuir monolayers

Ka Yee C. Lee

ANNUAL REVIEW OF PHYSICAL CHEMISTRY (2008)

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A comparative study of mechanisms of surfactant inhibition

Lasantha Gunasekara et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)

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Current perspectives in pulmonary surfactant - Inhibition, enhancement and evaluation

Yi Y. Zuo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)

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Structure of pulmonary surfactant membranes and films:: The role of proteins and lipid-protein interactions

Jesus Perez-Gil

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)

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Effect of acylation on the interaction of the N-Terminal segment of pulmonary surfactant protein SP-C with phospholipid membranes

I. Plasencia et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)

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Molecular dynamics simulations of lung surfactant lipid monolayers

Doyle Rose et al.

BIOPHYSICAL CHEMISTRY (2008)

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Influence of lipid saturation grade and headgroup charge: A refined lung surfactant adsorption model

U. Klenz et al.

BIOPHYSICAL JOURNAL (2008)

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Atomic force microscopy studies of functional and dysfunctional pulmonary surfactant films, II: Albumin-inhibited pulmonary surfactant films and the effect of SP-A

Yi Y. Zuo et al.

BIOPHYSICAL JOURNAL (2008)

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Metal nanoparticle pollutants interfere with pulmonary surfactant function in vitro

Mandeep Singh Bakshi et al.

BIOPHYSICAL JOURNAL (2008)

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Atomic force microscopy studies of functional and dysfunctional pulmonary surfactant films. I. Micro- and nanostructures of functional pulmonary surfactant films and the effect of SP-A

Yi Y. Zuo et al.

BIOPHYSICAL JOURNAL (2008)

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Line tensions, correlation lengths, and critical exponents in lipid membranes near critical points

Aurelia R. Honerkamp-Smith et al.

BIOPHYSICAL JOURNAL (2008)

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Effects of palmitoylation on dynamics and phospholipid-bilayer-perturbing properties of the N-terminal segment of pulmonary surfactant protein SP-C as shown by 2H-NMR

Azucena Gonzalez-Horta et al.

BIOPHYSICAL JOURNAL (2008)

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Surfactant in airway disease

Goran Enhorning

CHEST (2008)

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A Search for Subgroups of Patients With ARDS Who May Benefit From Surfactant Replacement Therapy A Pooled Analysis of Five Studies With Recombinant Surfactant Protein-C Surfactant (Venticute)

Friedemann J. H. Taut et al.

CHEST (2008)

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Pressure induces interdigitation differently in DPPC and DPPG

Harpreet Singh et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2008)

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Surfactant proteins B and C are both necessary for alveolar stability at end expiration in premature rabbits with respiratory distress syndrome

Andreas Almlen et al.

JOURNAL OF APPLIED PHYSIOLOGY (2008)

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Pepsinogen C proteolytic processing of surfactant protein B

Kristin D. Gerson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

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Proteomics of Human Lung Tissue Identifies Surfactant Protein A as a Marker of Chronic Obstructive Pulmonary Disease

Steffen Ohlmeler et al.

JOURNAL OF PROTEOME RESEARCH (2008)

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Surfactant collectins and innate immunity

Henk P. Haagsman et al.

NEONATOLOGY (2008)

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The effect of elevated dietary cholesterol on pulmonary surfactant function in adolescent mice

K. C. McCrae et al.

PEDIATRIC PULMONOLOGY (2008)

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Dexamethasone therapy in preterm infants developing bronchopulmonary dysplasia: Effect on pulmonary surfactant disaturated-phosphatidylcholine kinetics

Paola E. Cogo et al.

PEDIATRIC RESEARCH (2008)

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The molecular mechanism of lipid monolayer collapse

Svetlana Baoukina et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

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Review Physiology

The biophysical function of pulmonary surfactant

Sandra Rugonyi et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2008)

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Therapeutic effects of exogenous surfactant enriched with dextran in newborn rabbits with respiratory failure induced by airway instillation of albumin

A. Calkovska et al.

PULMONARY PHARMACOLOGY & THERAPEUTICS (2008)

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Lateral stress relaxation and collapse in lipid monolayers

Luka Pocivavsek et al.

SOFT MATTER (2008)

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The molecular mechanism of monolayer-bilayer transformations of lung surfactant from molecular dynamics simulations

Svetlana Baoukina et al.

BIOPHYSICAL JOURNAL (2007)

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The anatomy, physics, and physiology of gas exchange surfaces: is there a universal function for pulmonary surfactant in animal respiratory structures?

Sandra Orgeig et al.

INTEGRATIVE AND COMPARATIVE BIOLOGY (2007)

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Pulmonary collectins in innate immunity of the lung

Yoshio Kuroki et al.

CELLULAR MICROBIOLOGY (2007)

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Effect of cholesterol on the biophysical and physiological properties of a clinical pulmonary surfactant

Eleonora Keating et al.

BIOPHYSICAL JOURNAL (2007)

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Resolution of severe ischemia-reperfusion injury post-lung transplantation after administration of endobronchial surfactant

F. D. Kermeen et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2007)

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Regulation of surfactant secretion in alveolar type II cells

Alexandra V. Andreeva et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)

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Article Respiratory System

Patients with ARDS show improvement but not normalisation of alveolar surface activity with surfactant treatment: putative role of neutral lipids

Philipp Markart et al.

THORAX (2007)

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An elevated level of cholesterol impairs self-assembly of pulmonary surfactant into a functional film

Zoya Leonenko et al.

BIOPHYSICAL JOURNAL (2007)

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Modification of tryptophan and methionine residues is implicated in the oxidative inactivation of surfactant protein B

Dahis Manzanares et al.

BIOCHEMISTRY (2007)

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The melting of pulmonary surfactant monolayers

Wenfei Yan et al.

JOURNAL OF APPLIED PHYSIOLOGY (2007)

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Single giant vesicle rupture events reveal multiple mechanisms of glass-supported bilayer formation

Chiho Hamai et al.

BIOPHYSICAL JOURNAL (2007)

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Differential effects of lysophosphatidylcholine on the adsorption of phospholipids to an air/water interface

Samares C. Biswas et al.

BIOPHYSICAL JOURNAL (2007)

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Developmental changes in rat surfactant lipidomics in the context of species variability

Wolfgang Bernhard et al.

PEDIATRIC PULMONOLOGY (2007)

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Genetic disorders of surfactant proteins

Aaron Hamvas et al.

NEONATOLOGY (2007)

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Inherited surfactant protein-B deficiency and surfactant protein-C associated disease: Clinical features and evaluation

Aaron Hamvas

SEMINARS IN PERINATOLOGY (2006)

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Nucleation in monolayers

D. Vollhardt

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2006)

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The evolution of a physiological system: The pulmonary surfactant system in diving mammals

Natalie J. Foot et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2006)

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Cubic phases in phosphatidylcholine-cholesterol mixtures: Cholesterol as membrane fusogen''

Boris G. Tenchov et al.

BIOPHYSICAL JOURNAL (2006)

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Force measuring methods for determination of surface tension of liquids: A comparison

L. Richter et al.

TENSIDE SURFACTANTS DETERGENTS (2006)

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To see or not to see: Lateral organization of biological membranes and fluorescence microscopy

Luis A. Bagatolli

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)

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Physiological effects of oxidized exogenous surfactant in vivo: effects of high tidal volume and surfactant protein A

Timothy C. Bailey et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)

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Chitosan enhances the in vitro surface activity of dilute lung surfactant preparations and resists albumin-induced inactivation

Yi Y. Zuo et al.

PEDIATRIC RESEARCH (2006)

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The future of surfactant therapy during ALI/ARDS

James F. Lewis et al.

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

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Surfactant protein C: Its unique properties and emerging immunomodulatory role in the lung

Surafel Mulugeta et al.

MICROBES AND INFECTION (2006)

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Protein-lipid interactions and surface activity in the pulmonary surfactant system

Alicia G. Serrano et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2006)

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Effect of cholesterol depletion on exocytosis of alveolar type II cells

Narendranath Reddy Chintagari et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)

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Production and characterisation of recombinant forms of human pulmonary surfactant protein C (SP-C):: Structure and surface activity

Dunja Lukovic et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)

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Review Chemistry, Physical

NMR on lipid membranes and their proteins

Goran Lindblom et al.

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE (2006)

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Surfactant proteins SP-A and SP-D: Structure, function and receptors

U Kishore et al.

MOLECULAR IMMUNOLOGY (2006)

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Effect of average phospholipid curvature on supported bilayer formation on glass by vesicle fusion

C Hamai et al.

BIOPHYSICAL JOURNAL (2006)

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Critical structure-function determinants within the N-terminal region of pulmonary surfactant protein SP-B

AG Serrano et al.

BIOPHYSICAL JOURNAL (2006)

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Antimicrobial activity of native and synthetic surfactant protein B peptides

MA Ryan et al.

JOURNAL OF IMMUNOLOGY (2006)

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Use of transgenic mice to study lung morphogenesis and function

JP Bridges et al.

ILAR JOURNAL (2006)

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Exogenous surfactant therapy for ARDS

A Maruscak et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2006)

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Mechanisms to explain surfactant responses

AH Jobe

BIOLOGY OF THE NEONATE (2006)

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Surfactant catabolism

M Ikegami

RESPIROLOGY (2006)

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Structures of pulmonary surfactant films adsorbed to an air-liquid interface in vitro

H Bachofen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2005)

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Article Biochemistry & Molecular Biology

Lysophospholipid and fatty acid inhibition of pulmonary surfactant:: Non-enzymatic models of phospholipase A2 surfactant hydrolysis

RD Hite et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2005)

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Review Biochemistry & Molecular Biology

Seeing spots: Complex phase behavior in simple membranes

SL Veatch et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)

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Interfacial properties of pulmonary surfactant layers

R Wüstneck et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2005)

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The role of charged amphipathic helices in the structure and function of surfactant protein B

AJ Waring et al.

JOURNAL OF PEPTIDE RESEARCH (2005)

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Effects of gramicidin-A on the adsorption of phospholipids to the air-water interface

SC Biswas et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2005)

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Article Chemistry, Multidisciplinary

Effect of humidity on the adsorption kinetics of lung surfactant at air-water interfaces

YY Zuo et al.

LANGMUIR (2005)

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Dipalmitoylphosphatidylcholine is not the major surfactant phospholipid species in all mammals

CJ Lang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)

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Article Medicine, General & Internal

Incidence and outcomes of acute lung injury

GD Rubenfeld et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

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Pulmonary surfactant function is abolished by an elevated proportion of cholesterol

L Gunasekara et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2005)

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Article Biochemistry & Molecular Biology

Surface properties of sulfur- and ether-linked phosphonolipids with and without purified hydrophobic lung surfactant proteins

YS Chang et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2005)

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Inhibition of pulmonary surfactant adsorption by serum and the mechanisms of reversal by hydrophilic polymers: Theory

JA Zasadzinski et al.

BIOPHYSICAL JOURNAL (2005)

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Optical measurement of surface tension in a miniaturized air-liquid interface and its application in lung physiology

C Bertocchi et al.

BIOPHYSICAL JOURNAL (2005)

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Interaction of the N-terminal segment of pulmonary surfactant protein SP-C with interfacial phospholipid films

I Plasencia et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2005)

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Article Critical Care Medicine

Surfactant palmitoylmyristoylphosphatidylcholine is a marker for alveolar size during disease

R Ridsdale et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

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Article Biochemistry & Molecular Biology

Defective surfactant secretion in a mouse model of Hermansky-Pudlak syndrome

SH Guttentag et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2005)

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Article Chemistry, Multidisciplinary

Influence of a fluorescent probe on the nanostructure of phospholipid membranes:: Dipalmitoylphosphatidylcholine interfacial monolayers

A Cruz et al.

LANGMUIR (2005)

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Monolayer-multilayer transitions in a lung surfactant model: IR reflection-absorption spectroscopy and atomic force microscopy

L Wang et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2005)

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Article Biophysics

Complexes in ternary cholesterol-phospholipid mixtures

H McConnell

BIOPHYSICAL JOURNAL (2005)

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Surfactant-associated protein B kinetics in vivo in newborn infants by stable isotopes

P Cogo et al.

PEDIATRIC RESEARCH (2005)

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Surfactant and physiologic responses of preterm lambs to continuous positive airway pressure

N Mulrooney et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

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Article Physiology

Surfactant protein D influences surfactant ultrastructure and uptake by alveolar type II cells

M Ikegami et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)

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Article Medicine, General & Internal

Effect of exogenous surfactant (Calfactant) in pediatric acute lung injury - A randomized controlled trial

DF Willson et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

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Article Biochemistry & Molecular Biology

Mapping and analysis of the lytic and fusogenic domains of surfactant protein B

MA Ryan et al.

BIOCHEMISTRY (2005)

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Miscibility of ternary mixtures of phospholipids and cholesterol in monolayers, and application to bilayer systems

BL Stottrup et al.

BIOPHYSICAL JOURNAL (2005)

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Tracing surfactant transformation from cellular release to insertion into an air-liquid interface

T Haller et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)

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Article Multidisciplinary Sciences

Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition

JC Condon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

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Article Obstetrics & Gynecology

A randomized, multicenter masked comparison trial of poractant alfa (Curosurf) versus beractant (Survanta) in the treatment of respiratory distress syndrome in preterm infants

R Ramanathan et al.

AMERICAN JOURNAL OF PERINATOLOGY (2004)

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Proteolytic generation and aggregation of peptides from transmembrane regions:: lung surfactant protein C and amyloid β-peptide

J Johansson et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2004)

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Article Biochemistry & Molecular Biology

Cholesterol rules - Direct observation of the coexistence of two fluid phases in native pulmonary surfactant membranes at physiological temperatures

JB de la Serna et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

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Article Cardiac & Cardiovascular Systems

Plasma surfactant protein-B - A novel biomarker in chronic heart failure

CG De Pasquale et al.

CIRCULATION (2004)

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Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome

RG Spragg et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

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Constrained sessile drop as a new configuration to measure low surface tension in lung surfactant systems

LMY Yu et al.

JOURNAL OF APPLIED PHYSIOLOGY (2004)

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Improvement of interfacial tension measurement using a captive bubble in conjunction with axisymmetric drop shape analysis (ADSA)

YY Zuo et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2004)

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Article Biochemistry & Molecular Biology

Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin

N Palaniyar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

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Article Respiratory System

In vivo clearance of surfactant lipids during acute pulmonary inflammation.

JL Malloy et al.

RESPIRATORY RESEARCH (2004)

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Disparate effects of two phosphatidylcholine binding proteins, C-reactive protein and surfactant protein A, on pulmonary surfactant structure and function

K Nag et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)

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Article Biochemistry & Molecular Biology

Further development of Axisymmetric Drop Shape Analysis-Captive Bubble for pulmonary surfactant related studies

YY Zuo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2004)

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Article Biochemistry & Molecular Biology

The N-terminal segment of pulmonary surfactant lipopeptide SP-C has intrinsic propensity to interact with and perturb phospholipid bilayers

I Plasencia et al.

BIOCHEMICAL JOURNAL (2004)

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Article Biophysics

Effect of pulmonary surfactant protein SP-B on the micro- and nanostructure of phospholipid films

A Cruz et al.

BIOPHYSICAL JOURNAL (2004)

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Article Biochemistry & Molecular Biology

Surfactant in newborn compared with adolescent pigs - Adaptation to neonatal respiration

GA Rau et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2004)

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Article Endocrinology & Metabolism

Elevation of lung surfactant phosphatidylcholine in mouse models of Sandhoff and of Niemann-Pick A disease

R Buccoliero et al.

JOURNAL OF INHERITED METABOLIC DISEASE (2004)

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Physiological and inflammatory response to instillation of an oxidized surfactant in a rat model of surfactant deficiency

TC Bailey et al.

JOURNAL OF APPLIED PHYSIOLOGY (2004)

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Deacylated pulmonary surfactant protein SP-C transforms from α-helical to amyloid fibril structure via a pH-dependent mechanism:: An infrared structural investigation

RA Dluhy et al.

BIOPHYSICAL JOURNAL (2003)

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SP-B deficiency causes respiratory failure in adult mice

KR Melton et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)

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Article Physiology

Pulmonary surfactant: The key to the evolution of air breathing

CB Daniels et al.

NEWS IN PHYSIOLOGICAL SCIENCES (2003)

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Article Biochemistry & Molecular Biology

Pulmonary surfactant protein-A (SP-A) restores the surface properties of surfactant after oxidation by a mechanism that requires the Cys6 interchain disulfide bond and the phospholipid binding domain

KR Capote et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

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Liquid-crystalline collapse of pulmonary surfactant monolayers

WR Schief et al.

BIOPHYSICAL JOURNAL (2003)

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Molecular organization revealed by time-of-flight secondary ion mass spectrometry of a clinically used extracted pulmonary surfactant

RR Harbottle et al.

LANGMUIR (2003)

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Role of cholesterol in lipid raft formation: lessons from lipid model systems

JR Silvius

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2003)

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Article Biochemistry & Molecular Biology

Lipid compositional analysis of pulmonary surfactant monolayers and monolayer-associated reservoirs

SH Yu et al.

JOURNAL OF LIPID RESEARCH (2003)

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Effects of oligomerization and secondary structure on the surface behavior of pulmonary surfactant proteins SP-B and SP-C

N Wüstneck et al.

BIOPHYSICAL JOURNAL (2003)

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Laplace's law and the alveolus: A misconception of anatomy and a misapplication of physics

HD Prange

ADVANCES IN PHYSIOLOGY EDUCATION (2003)

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Review Physiology

Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolase

M Nanjundan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)

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Article Biophysics

Effect of hydrophobic surfactant proteins SP-B and SP-C on binary phospholipid monolayers II. Infrared external reflectance-absorption spectroscopy

JM Brockman et al.

BIOPHYSICAL JOURNAL (2003)

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Metastability of a supercompressed fluid monolayer

EC Smith et al.

BIOPHYSICAL JOURNAL (2003)

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Review Physiology

The role of exogenous surfactant in the treatment of acute lung injury

JE Lewis et al.

ANNUAL REVIEW OF PHYSIOLOGY (2003)

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Increase of inactive intra-alveolar surfactant subtypes in lungs of asthmatic Brown Norway rats

A Schmiedl et al.

VIRCHOWS ARCHIV (2003)

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Mechanisms of disease: Hydrophobic surfactant proteins in lung function and disease

JA Whitsett et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)

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Article Biochemistry & Molecular Biology

Effects of cholesterol on surface activity and surface topography of spread surfactant films

RV Diemel et al.

BIOCHEMISTRY (2002)

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Article Biochemistry & Molecular Biology

Effect of hydrophobic surfactant protein SP-C on binary phospholipid monolayers.: Molecular machinery at the air/water interface

P Krüger et al.

BIOPHYSICAL CHEMISTRY (2002)

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Article Physiology

Altered fatty acid composition of lung surfactant phospholipids in interstitial lung disease

R Schmidt et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2002)

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Review Biochemistry & Molecular Biology

Pulmonary surfactant: phase behavior and function

B Piknova et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2002)

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Segregation of saturated chain lipids in pulmonary surfactant films and bilayers

K Nag et al.

BIOPHYSICAL JOURNAL (2002)

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Article Critical Care Medicine

Polyethylene glycol (PEG) attenuates exogenous surfactant in lung-injured adult rabbits

H Campbell et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)

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Article Biochemistry & Molecular Biology

Torpor-associated fluctuations in surfactant activity in Gould's wattled bat

JR Codd et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2002)

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Article Biochemistry & Molecular Biology

Intracellular and intraalveolar localization of surfactant protein a (SP-A) in the parenchymal region of the human lung

M Ochs et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)

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Article Respiratory System

Evaluation of alveolar surfactant aggregates in vitro and in vivo

AM Brackenbury et al.

EUROPEAN RESPIRATORY JOURNAL (2002)

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Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis

KE Greene et al.

EUROPEAN RESPIRATORY JOURNAL (2002)

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Article Biochemistry & Molecular Biology

Phosphatidylcholine molecular species in lung surfactant - Composition in relation to respiratory rate and lung development

W Bernhard et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)

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Article Biochemistry & Molecular Biology

Thermal stability and DPPC/Ca2+ interactions of pulmonary surfactant SP-A from bulk-phase and monolayer IR spectroscopy

XH Bi et al.

BIOCHEMISTRY (2001)

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Article Biochemistry & Molecular Biology

Superficial disposition of the N-terminal region of the surfactant protein SP-C and the absence of specific SP-B-SP-C interactions in phospholipid bilayers

I Plasencia et al.

BIOCHEMICAL JOURNAL (2001)

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Review Critical Care Medicine

Pulmonary surfactant:: functions, abnormalities and therapeutic options

I Frerking et al.

INTENSIVE CARE MEDICINE (2001)

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The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse

M Ikegami et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

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Discrepancy between phase behavior of lung surfactant phospholipids and the classical model of surfactant function

B Piknova et al.

BIOPHYSICAL JOURNAL (2001)

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Article Obstetrics & Gynecology

Biology of surfactant

AH Jobe et al.

CLINICS IN PERINATOLOGY (2001)

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Secretion in alveolar type II cells at the interface of constitutive and regulated exocytosis

M Frick et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)

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Article Physiology

Surfactant protein interactions with neutral and acidic phospholipid films

K Rodriguez-Capote et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

Membrane activity of (Cys48Ser) lung surfactant protein B increases with dimerisation

S Zaltash et al.

BIOLOGICAL CHEMISTRY (2001)

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Article Physiology

Macrophage and type II cell catabolism of SP-A and saturated phosphatidylcholine in mouse lungs

O Gurel et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)

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Article Multidisciplinary Sciences

Altered stability of pulmonary surfactant in SP-C-deficient mice

SW Glasser et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

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Article Biochemistry & Molecular Biology

Surface activity in situ, in vivo, and in the captive bubble surfactometer

S Schurch et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

Surface activity in vitro:: role of surfactant proteins

F Possmayer et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

A comparison of the molecular species compositions of mammalian lung surfactant phospholipids

AD Postle et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

The roles of cholesterol in pulmonary surfactant, insights from comparative and evolutionary studies

S Orgeig et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

Domains of surfactant protein A that affect protein oligomerization, lipid structure and surface tension

N Palaniyar et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

Alveolar surface forces and lung architecture

H Bachofen et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

Surfactant in respiratory distress syndrome and lung injury

M Hallman et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY (2001)

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Article Biochemistry & Molecular Biology

Pulmonary surfactant function studied with the pulsating bubble surfactometer (PBS) and the capillary surfactometer (CS)

G Enhorning

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY (2001)

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Article Biophysics

Effects of lung surfactant proteins, SP-B and SP-C, and palmitic acid on monolayer stability

JQ Ding et al.

BIOPHYSICAL JOURNAL (2001)

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Article Biochemistry & Molecular Biology

The comparative biology of pulmonary surfactant: past, present and future

CB Daniels et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2001)

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Article Biophysics

Rapid compression transforms interfacial monolayers of pulmonary surfactant

JM Crane et al.

BIOPHYSICAL JOURNAL (2001)

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Article Respiratory System

Effects of mechanical ventilation of isolated mouse lungs on surfactant and inflammatory cytokines

RAW Veldhuizen et al.

EUROPEAN RESPIRATORY JOURNAL (2001)

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Review Physiology

The pulmonary collectins and surfactant metabolism

S Hawgood et al.

ANNUAL REVIEW OF PHYSIOLOGY (2001)

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Review Respiratory System

Surfactant alteration and replacement in acute respiratory distress syndrome

A Gunther et al.

RESPIRATORY RESEARCH (2001)

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Article Critical Care Medicine

Commercial versus native surfactants - Surface activity, molecular components, and the effect of calcium

W Bernhard et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)

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Article Physiology

Tolerance of SP-A-deficient mice to hyperoxia or exercise

M Ikegami et al.

JOURNAL OF APPLIED PHYSIOLOGY (2000)

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Article Critical Care Medicine

Separation of alveolar surfactant into subtypes - A comparison of methods

NJ Gross et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)

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Article Biophysics

Analysis of lung surfactant model systems with time-of-flight secondary ion mass spectrometry

N Bourdos et al.

BIOPHYSICAL JOURNAL (2000)

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Article Critical Care Medicine

Pulmonary surfactant is altered during mechanical ventilation of isolated rat lung

RAW Veldhuizen et al.

CRITICAL CARE MEDICINE (2000)

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Article Physiology

Incorporation of biotinylated SP-A into rat lung surfactant layer, type II cells, and Clara cells

J Savov et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2000)

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Article Physiology

[Ca2+]i oscillations regulate type II cell exocytosis in the pulmonary alveolus

Y Ashino et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2000)

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Article Critical Care Medicine

Exogenous surfactant kinetics in infant respiratory distress syndrome: A novel method with stable isotopes

M Torresin et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)

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Article Biochemistry & Molecular Biology

Ablation of a critical surfactant protein B intramolecular disulfide bond in transgenic mice

DC Beck et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

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Article Physiology

Effects of ventilation on the surfactant system in sepsis-induced lung injury

JL Malloy et al.

JOURNAL OF APPLIED PHYSIOLOGY (2000)

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Article Genetics & Heredity

Polymorphisms of human SP-A, SP-B, and SP-D genes: association of SP-B Thr131Ile with ARDS

Z Lin et al.

CLINICAL GENETICS (2000)

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Article Biophysics

Distinct steps in the adsorption of pulmonary surfactant to an air-liquid interface

RW Walters et al.

BIOPHYSICAL JOURNAL (2000)

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