4.7 Article

A multifunctional phosphorescent iridium(III) complex for specific nucleus staining and hypoxia monitoring

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 37, Pages 7943-7946

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc01978h

Keywords

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Funding

  1. National Basic Research Program of China [2012CB933301]
  2. National Natural Science Foundation of China [21171098, 51473078]
  3. Program for New Century Excellent Talents in University [NCET-12-0740]
  4. Ministry of Education of China [IRT1148, 20133223110006]
  5. Natural Science Foundation of Jiangsu Province of China [BK20130038, BM2012010]
  6. Priority Academic Program Development of Jiangsu Higher Education Institutions [YX03001]

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A multifunctional phosphorescent iridium(III) complex (Ir1) for specific nucleus staining was synthesized and applied for monitoring the intranuclear oxygen level. With the advantageous long emission lifetime of Ir1, the influence of autofluorescence could be eliminated by using photoluminescence lifetime imaging and time-gated luminescence imaging techniques.

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