4.7 Article

Photosensitizer conjugated iron oxide nanoparticles for simultaneous in vitro magneto-fluorescent imaging guided photodynamic therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 26, Pages 5687-5690

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc10444g

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Funding

  1. National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology [NRF-2010-0021427, NRF-2012R1A2A1A01012042]

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In this study, photosensitizer conjugated iron oxide nanoparticles were strategically designed and prepared for simultaneous PDT and dual-mode fluorescence/MR imaging. The MRI contrast agent Fe3O4 was modified by APTES to functionalize the surface and further to link with heparin-pheophorbide-A conjugates.

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