4.1 Article

Accelerated wound healing with resveratrol-loaded decellularized pericardium in mice model

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

The anti-cancer effect of chitosan/resveratrol polymeric nanocomplex against triple-negative breast cancer; an in vitro assessment

Azam Bozorgi et al.

Summary: In this study, chitosan nanoparticles were synthesized as a carrier for resveratrol and their effectiveness in inducing apoptosis in MDA-MB 231 cells was evaluated. The results showed that the synthesized nanoparticles had low cytotoxicity and were able to inhibit cell proliferation by targeting mitochondrial metabolism and inducing the intrinsic apoptotic pathway.

IET NANOBIOTECHNOLOGY (2023)

Review Anatomy & Morphology

Exosomes and exosome-loaded scaffolds: Characterization and application in modern regenerative medicine

Fatemeh Khazaei et al.

Summary: Exosomes are extracellular vesicles derived from endosomes that have gained attention for their potential use in regenerative therapies and tissue repair. However, their poor bioavailability and lack of controlled-release mechanisms have been addressed by scaffolding them with biomaterials to create Exosomes-loaded scaffolds (ELS). These biomaterial-based scaffolds can be designed and functionalized to improve the bioavailability, biocompatibility, and controlled release of Exosomes.

TISSUE & CELL (2023)

Article Pharmacology & Pharmacy

Development and evaluation of Resveratrol-loaded liposomes in hydrogel-based wound dressing for diabetic foot ulcer

Supriya Pandey et al.

Summary: Diabetic foot ulcers (DFUs) are a common complication of poorly controlled diabetes, and this study explores the use of RV-loaded liposomes in a hydrogel-based wound dressing to accelerate the healing of DFUs.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2023)

Article Medicine, Research & Experimental

Resveratrol: Targeting cancer stem cells and ncRNAs to overcome cancer drug resistance

Leila Rezakhani et al.

CURRENT MOLECULAR MEDICINE (2023)

Article Chemistry, Applied

Hybrid PCL/chitosan-PEO nanofibrous scaffolds incorporated with A. euchroma extract for skin tissue engineering application

Fatemeh Asghari et al.

Summary: In this study, a new hybrid nanofibrous scaffold composed of polycaprolactone/chitosan-polyethylene oxide (PCL/Cs-PEO) incorporated with Arnebia euchroma (A. euchroma) extract was synthesized by the two-nozzle electrospinning method. The scaffold showed improved and increased proliferation of skin cells in vitro, confirming its potential for skin tissue engineering.

CARBOHYDRATE POLYMERS (2022)

Review Chemistry, Medicinal

The Use of Textiles in the Wound Healing: A Review

Janaina Ribeiro Oliveira et al.

Summary: This article reviews the impact of textiles on the wound healing process and their availability in the market. It discusses the applications, historical context, general characteristics, and incorporation of new technologies in wound textiles. The study suggests that textiles and associated technologies can have direct or indirect effects on collagen stimulation, cell migration, angiogenesis, and reduction of inflammatory factors and fibroblasts. However, the mechanisms by which textiles contribute to the healing process are not well-established in the literature. The interdisciplinary collaboration among textile engineering, biotechnology, medicine, and pharmacology is crucial for developing more efficient and accessible products.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2022)

Article Biotechnology & Applied Microbiology

Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture

Michael A. David et al.

Summary: In two preclinical models of elbow post-traumatic joint contracture, simvastatin (SV) may be a suitable prophylactic drug therapy, while losartan (LS) does not have the same effect. These findings provide initial insight for future studies aimed at preventing or mitigating elbow post-traumatic joint contracture.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)

Article Cell Biology

The effect of Scrophularia striata on cell attachment and biocompatibility of decellularized bovine pericardia

Morteza Alizadeh et al.

Summary: This study demonstrated that using Scrophularia striata extract significantly increased cell survival rate and attachment on decellularized pericardia, paving the way for the use of herbal plant extracts to enhance the application of decellularized tissues.

CELL AND TISSUE BANKING (2022)

Article Biotechnology & Applied Microbiology

Cell loaded hydrogel containing Ag-doped bioactive glass-ceramic nanoparticles as skin substitute: Antibacterial properties, immune response, and scarless cutaneous wound regeneration

Esmaeel Sharifi et al.

Summary: This study developed a tissue-engineered dermal substitute with antibacterial and wound healing-promoting properties. The substitute consisted of nanofibrous scaffolds and silver-doped glass-ceramic. The substitute exhibited good biocompatibility and hemocompatibility, promoting cell attachment and proliferation without inducing an inflammatory response. The degradation rate of the substitute matched the rate of skin regeneration under in vivo conditions. In a mouse model, the substitute promoted angiogenesis, collagen synthesis, and regeneration of sebaceous glands and hair follicles.

BIOENGINEERING & TRANSLATIONAL MEDICINE (2022)

Article Dermatology

Wound Healing Activities of Gundelia tournefortii L Extract and Milk-Cream Ointment on Second-Degree Burns of Rat Skin

Setareh Javanmardi et al.

Summary: The study evaluated the effect of Gundelia tournefortii L extract composite with milk-cream on the healing of second-degree burn in a rat model, and found that it significantly improved burn healing compared to other treatments. This suggests that it could be a complementary and/or alternative medicine in wound healing.

INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS (2021)

Article Cell & Tissue Engineering

Evaluating the effects of vacuum on the microstructure and biocompatibility of bovine decellularized pericardium

Morteza Alizadeh et al.

Summary: The study evaluated the effects of vacuum on the microstructure and biocompatibility of bovine decellularized pericardium. Vacuum treatment reduced residual DNA, increased pore size and porosity, enhanced cell viability, and reduced inflammation post-implantation. Further studies are needed to optimize the time, intensity, and application method of vacuum in decellularization processes.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2021)

Article Pharmacology & Pharmacy

Resveratrol Effect on Adipose-Derived Stem Cells Differentiation to Chondrocyte in Three-Dimensional Culture

Ghazal Keshavarz et al.

ADVANCED PHARMACEUTICAL BULLETIN (2020)

Article Pharmacology & Pharmacy

Resveratrol Promotes Diabetic Wound Healing via SIRT1-FOXO1-c-Myc Signaling Pathway-Mediated Angiogenesis

Xiaozhong Huang et al.

FRONTIERS IN PHARMACOLOGY (2019)

Review Biotechnology & Applied Microbiology

Recent advances on biomedical applications of scaffolds in wound healing and dermal tissue engineering

Azizeh Rahmani Del Bakhshayesh et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

Article Engineering, Biomedical

A bilayer scaffold prepared from collagen and carboxymethyl cellulose for skin tissue engineering applications

Cemile Kilic Bektas et al.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2018)

Review Biochemistry & Molecular Biology

Role of resveratrol in regulation of cellular defense systems against oxidative stress

Van-Long Truong et al.

BIOFACTORS (2018)

Article Dermatology

Reconsidering the H&E stain as the gold standard in assessing the depth of burn wounds

Arlene S. Rosenberg

JOURNAL OF CUTANEOUS PATHOLOGY (2017)

Article Dermatology

Dermal Fibroblasts Promote Alternative Macrophage Activation Improving Impaired Wound Healing

Ruben A. Ferrer et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)

Review Biotechnology & Applied Microbiology

Therapeutic potential of resveratrol: the in vivo evidence

Joseph A. Baur et al.

NATURE REVIEWS DRUG DISCOVERY (2006)