☆ 4.7 Article

Versatile click alginate hydrogels with protease-sensitive domains as cell responsive/instructive 3D microenvironments

CARBOHYDRATE POLYMERS (2023)

Related references

Note: Only part of the references are listed.

Article Engineering, Biomedical

Microstructured click hydrogels for cell contact guidance in 3D

Mariana I. Neves et al.

Summary: This study reports the design of microstructured alginate hydrogels for injectable cell delivery and demonstrates their ability to guide cell morphogenesis through cellular contact guidance in a 3D setting. Alginate was modified with hydrophobic cyclooctyne groups to generate self-associative amphiphilic derivatives capable of forming microstructured hydrogels. MSCs embedded in the hydrogels were able to sense and respond to the 3D topography, regulating their shape and stress fiber organization.

MATERIALS TODAY BIO (2023)

Add to Collection

Review Engineering, Biomedical

Inflammation-me diate d matrix remodeling of extracellular matrix-mimicking biomaterials in tissue engineering and regenerative medicine

Mimi Xu et al.

Summary: Extracellular matrix (ECM)-mimicking biomaterials are considered effective scaffolds for tissue engineering and regenerative medicine. However, dysregulation of matrix remodeling can lead to various pathological conditions. This review summarizes the characteristics of inflammatory responses in matrix remodeling after transplantation of ECM-mimicking biomaterials and discusses the intrinsic linkages between matrix remodeling and tissue regeneration. Understanding host immune responses to matrix remodeling is crucial for directing effective tissue regeneration. Further studies on the effects of clinical characteristics on matrix remodeling are needed.

ACTA BIOMATERIALIA (2022)

Add to Collection

Review Chemistry, Multidisciplinary

A Survey of Strain-Promoted Azide-Alkyne Cycloaddition in Polymer Chemistry

Kelvin Li et al.

Summary: Efficient reactions driving progress in synthetic chemistry focus on mild conditions, no by-products, and rapid completion. The strain-promoted azide-alkyne cycloaddition has gained popularity in organic synthesis, bioorthogonal chemistry, and polymer chemistry, leading to significant achievements in producing various polymeric constructs for diverse applications.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

Add to Collection

Article Engineering, Biomedical

Engineering injectable vascularized tissues from the bottom-up: Dynamics of in-gel extra-spheroid dermal tissue assembly

Talia Feijao et al.

Summary: Modular tissue engineering using spheroids as building blocks offers exciting possibilities for creating vascularized tissues from the bottom-up. A new injectable approach combining fibroblasts and endothelial progenitors has been developed to generate dense vascularized dermal tissue, showing promising results for clinical applications.

BIOMATERIALS (2021)

Add to Collection

Review Health Care Sciences & Services

Current Trends in Advanced Alginate-Based Wound Dressings for Chronic Wounds

Andreea Barbu et al.

Summary: Chronic wounds pose a major public health issue with high costs globally. An ideal wound dressing should possess various characteristics such as adhesion, non-antigenicity, biocompatibility, semi-permeability, and biodegradability. This paper explores the use of biopolymer materials, specifically alginate forms, in advanced wound healing applications, focusing on hydrogels, nanofibers networks, and 3D-scaffolds.

JOURNAL OF PERSONALIZED MEDICINE (2021)

Add to Collection

Article Multidisciplinary Sciences

Bioorthogonal chemistry

Samuel L. Scinto et al.

Summary: Bioorthogonal chemistry involves high-yielding chemical reactions in biological environments that are rapid and selective, playing essential roles in various fields such as biomedical imaging and drug delivery. Its applications are diverse and include genetic code expansion, drug target identification, and antibody-drug conjugation.

NATURE REVIEWS METHODS PRIMERS (2021)

Add to Collection

Article Nanoscience & Nanotechnology

Copper-Free Azide-Alkyne Cycloaddition for Peptide Modification of Alginate Hydrogels

Era Jain et al.

Summary: Alginate, a biocompatible polymer derived from algae, is often used in tissue engineering as a synthetic version of the extracellular matrix. This study developed a copper-free, strain-promoted azide-alkyne cycloaddition (SPAAC)-mediated method to conjugate azide-modified adhesive peptides (Az-cRGD) onto alginate, improving peptide bioactivity and enhancing osteogenesis in 3D alginate gels. This approach overcomes limitations of previous bioconjugation methods and has the potential to expand ligand possibilities for tissue engineering applications.

ACS APPLIED BIO MATERIALS (2021)

Add to Collection

Article Engineering, Biomedical

Dual alginate crosslinking for local patterning of biophysical and biochemical properties

Aline Lueckgen et al.

ACTA BIOMATERIALIA (2020)

Add to Collection

Review Chemistry, Applied

Egg-box model-based gelation of alginate and pectin: A review

Lianqi Cao et al.

CARBOHYDRATE POLYMERS (2020)

Add to Collection

Review Engineering, Biomedical

Extracellular Matrix-Based Strategies for Immunomodulatory Biomaterials Engineering

Andrew T. Rowley et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Add to Collection

Review Chemistry, Multidisciplinary

Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo

Eunha Kim et al.

CHEMICAL SCIENCE (2019)

Add to Collection

Article Engineering, Biomedical

Guiding morphogenesis in cell-instructive microgels for therapeutic angiogenesis

A. L. Torres et al.

BIOMATERIALS (2018)

Add to Collection

Article Chemistry, Physical

Rheological characterization of dynamic remodeling of the pericellular region by human mesenchymal stem cell-secreted enzymes in well-defined synthetic hydrogel scaffolds

Maryam Daviran et al.

SOFT MATTER (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Modulating Viscoelasticity, Stiffness, and Degradation of Synthetic Cellular Niches via Stoichiometric Tuning of Covalent versus Dynamic Noncovalent Cross-Linking

Yu Tan et al.

ACS CENTRAL SCIENCE (2018)

Add to Collection

Article Multidisciplinary Sciences

Folding driven self-assembly of a stimuli-responsive peptide-hyaluronan hybrid hydrogel

Robert Selegard et al.

SCIENTIFIC REPORTS (2017)

Add to Collection

Article Engineering, Biomedical

Bio-orthogonal conjugation and enzymatically triggered release of proteins within multi-layered hydrogels

Chen Guo et al.

ACTA BIOMATERIALIA (2017)

Add to Collection

Review Chemistry, Multidisciplinary

Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides

Jan Dommerholt et al.

TOPICS IN CURRENT CHEMISTRY (2016)

Add to Collection

Article Materials Science, Biomaterials

Biofunctionalized pectin hydrogels as 3D cellular microenvironments

Sara C. Neves et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

Add to Collection

Review Dermatology

Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring

Meilang Xue et al.

ADVANCES IN WOUND CARE (2015)

Add to Collection

Review Engineering, Biomedical

Injectable alginate hydrogels for cell delivery in tissue engineering

Silvia J. Bidarra et al.

ACTA BIOMATERIALIA (2014)

Add to Collection

Article Engineering, Biomedical

Matrix-driven formation of mesenchymal stem cell-extracellular matrix microtissues on soft alginate hydrogels

F. Raquel Maia et al.

ACTA BIOMATERIALIA (2014)

Add to Collection

Article Biochemistry & Molecular Biology

Injectable MMP-Sensitive Alginate Hydrogels as hMSC Delivery Systems

Keila B. Fonseca et al.

BIOMACROMOLECULES (2014)

Add to Collection

Article Chemistry, Multidisciplinary

Hydrogel depots for local co-delivery of osteoinductive peptides and mesenchymal stem cells

F. Raquel Maia et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Add to Collection

Review Polymer Science

Engineering proteolytically-degradable artificial extracellular matrices

Keila B. Fonseca et al.

PROGRESS IN POLYMER SCIENCE (2014)

Add to Collection

Article Biochemistry & Molecular Biology

In Situ Cross-Linkable Hydrogel of Hyaluronan Produced via Copper-Free Click Chemistry

Akira Takahashi et al.

BIOMACROMOLECULES (2013)

Add to Collection

Review Oncology

Fibroblast morphogenesis on 3D collagen matrices: The balance between cell clustering and cell migration

Bruno da Rocha-Azevedo et al.

EXPERIMENTAL CELL RESEARCH (2013)

Add to Collection

Article Chemistry, Physical

Enzymatic, physicochemical and biological properties of MMP-sensitive alginate hydrogels

Keila B. Fonseca et al.

SOFT MATTER (2013)

Add to Collection

Article Biochemical Research Methods

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin et al.

NATURE METHODS (2012)

Add to Collection

Article Engineering, Biomedical

Molecularly designed alginate hydrogels susceptible to local proteolysis as three-dimensional cellular microenvironments

Keila B. Fonseca et al.

ACTA BIOMATERIALIA (2011)

Add to Collection

Article Engineering, Biomedical

Injectable in situ crosslinkable RGD-modified alginate matrix for endothelial cells delivery

Silvia J. Bidarra et al.

BIOMATERIALS (2011)

Add to Collection

Article Biochemistry & Molecular Biology

Strain-Promoted Alkyne-Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate Biosynthesis

Ngalle Eric Mbua et al.

CHEMBIOCHEM (2011)

Add to Collection

Article Respiratory System

Biological role of matrix metalloproteinases: a critical balance

S. Loeffek et al.

EUROPEAN RESPIRATORY JOURNAL (2011)

Add to Collection

Article Chemistry, Multidisciplinary

Cellular Consequences of Copper Complexes Used To Catalyze Bioorthogonal Click Reactions

David C. Kennedy et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Add to Collection

Article Engineering, Biomedical

The effect of matrix characteristics on fibroblast proliferation in 3D gels

Katrin Bott et al.

BIOMATERIALS (2010)

Add to Collection

Article Engineering, Biomedical

Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix

Marta B. Evangelista et al.

BIOMATERIALS (2007)

Add to Collection

Article Chemistry, Physical

Altering associations in aqueous solutions of a hydrophobically modified alginate in the presence of β-cyclodextrin monomers

C Galant et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2006)

Add to Collection

Article Engineering, Biomedical

Alginate type and RGD density control myoblast phenotype

JA Rowley et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH (2002)

Add to Collection

Article Chemistry, Physical

Hydrophobically associating alginate derivatives: Surface tension properties of their mixed aqueous solutions with oppositely charged surfactants

VG Babak et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.