Journal
BLOOD
Volume 141, Issue 21, Pages 2546-2547Publisher
AMER SOC HEMATOLOGY
DOI: 10.1182/blood.2023020050
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The study found that enforcing CXCR4 expression on CD33-targeting CAR CIK cells enhances their homing to the bone marrow and improves their activity against AML.
In this issue of Blood, Biondi et al(1) show that enforcing CXCR4 expression on CD33-targeting chimeric antigen receptor (CAR) cytokine-induced killer (CIK) cells enhances their homing to the bone marrow (BM) and improves their activity against acute myeloid leukemia (AML).
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