How prostate-specific membrane antigen positron emission tomography is refining risk calculators in the primary prostate diagnostic pathway

Article Urology & Nephrology

A Novel Risk Calculator Incorporating Clinical Parameters, Multiparametric Magnetic Resonance Imaging, and Prostate-Specific Membrane Antigen Positron Emission Tomography for Prostate Cancer Risk Stratification Before Transperineal Prostate Biopsy

Brian D. Kelly et al.

Summary: A novel risk calculator using clinical parameters and imaging parameters from mpMRI and PSMA PET/CT was developed to predict the risk of clinically significant prostate cancer. The risk calculator incorporating PSMA PET/CT data showed better performance in predicting the detection and grading of prostate cancer compared to the calculator incorporating mpMRI data alone.

EUROPEAN UROLOGY OPEN SCIENCE (2023)

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Review Urology & Nephrology

A Systematic Review of the Variability in Performing and Reporting Intraprostatic Prostate-specific Membrane Antigen Positron Emission Tomography in Primary Staging Studies

Gideon Ptasznik et al.

Summary: There is significant variability in performing and reporting prostate-specific membrane antigen (PSMA) positron emission tomography (PET). Standardization of PSMA PET is required to improve its consistency and reproducibility for the diagnosis of prostate cancer (PCa).

EUROPEAN UROLOGY OPEN SCIENCE (2023)

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Editorial Material Urology & Nephrology

The Additive Diagnostic Value of Prostate-specific Membrane Antigen Positron Emission Tomography Computed Tomography to Multiparametric Magnetic Resonance Imaging Triage in the Diagnosis of Prostate Cancer (PRIMARY): A Prospective Multicentre Study

Louise Emmett et al.

Summary: The combination of PSMA + MRI shows higher negative predictive value and sensitivity for detecting clinically significant prostate cancer compared to MRI alone, but with a lower specificity. Combined PSMA + MRI may help avoid unnecessary prostate biopsies in some men.

EUROPEAN UROLOGY (2021)

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Article Urology & Nephrology

Prediction of High-grade Prostate Cancer Following Multiparametric Magnetic Resonance Imaging: Improving the Rotterdam European Randomized Study of Screening for Prostate Cancer Risk Calculators

Arnout R. Alberts et al.

EUROPEAN UROLOGY (2019)

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Article Urology & Nephrology

A multiparametric magnetic resonance imaging-based risk model to determine the risk of significant prostate cancer prior to biopsy

Pim J. van Leeuwen et al.

BJU INTERNATIONAL (2017)

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Editorial Material Urology & Nephrology

The Benefits of Risk Assessment Tools for Prostate Cancer

Ian M. Thompson et al.

EUROPEAN UROLOGY (2012)

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How prostate-specific membrane antigen positron emission tomography is refining risk calculators in the primary prostate diagnostic pathway

Related references

A Novel Risk Calculator Incorporating Clinical Parameters, Multiparametric Magnetic Resonance Imaging, and Prostate-Specific Membrane Antigen Positron Emission Tomography for Prostate Cancer Risk Stratification Before Transperineal Prostate Biopsy

A Systematic Review of the Variability in Performing and Reporting Intraprostatic Prostate-specific Membrane Antigen Positron Emission Tomography in Primary Staging Studies

The Additive Diagnostic Value of Prostate-specific Membrane Antigen Positron Emission Tomography Computed Tomography to Multiparametric Magnetic Resonance Imaging Triage in the Diagnosis of Prostate Cancer (PRIMARY): A Prospective Multicentre Study

Prediction of High-grade Prostate Cancer Following Multiparametric Magnetic Resonance Imaging: Improving the Rotterdam European Randomized Study of Screening for Prostate Cancer Risk Calculators

A multiparametric magnetic resonance imaging-based risk model to determine the risk of significant prostate cancer prior to biopsy

The Benefits of Risk Assessment Tools for Prostate Cancer

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