Journal
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
Volume -, Issue -, Pages -Publisher
WILEY
DOI: 10.1111/1471-0528.17687
Keywords
air pollution; endocrine disorders; endometriosis; environment; occupational pollution; pollution; public health; public policies; water pollution; women
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This article reviews the relationship between pollution and endometriosis, highlighting the impact of environmental factors on the development and severity of the disease, and emphasizing the need for comprehensive measures to protect women's reproductive health.
BackgroundThe interaction between pollution and endometriosis is a pressing issue that demands immediate attention. The impact of pollution, particularly air and water pollution, or occupational hazards, on hormonal disruption and the initiation of endometriosis remains a major issue.ObjectivesThis narrative review aims to delve into the intricate connection between pollution and endometriosis, shedding light on how environmental factors contribute to the onset and severity of this disease and, thus, the possible public health policy implications.DiscussionEndocrine-disrupting chemicals (EDCs) in pollutants dysregulate the hormonal balance, contributing to the progression of this major gynaecological disorder. Air pollution, specifically PM2.5 and PAHs, has been associated with an increased risk of endometriosis by enhancing chronic inflammation, oxidative stress, and hormonal imbalances. Chemical contaminants in water and work exposures, including heavy metals, dioxins, and PCBs, disrupt the hormonal regulation and potentially contribute to endometriosis. Mitigating the environmental impact of pollution is required to safeguard women's reproductive health. This requires a comprehensive approach involving stringent environmental regulations, sustainable practices, responsible waste management, research and innovation, public awareness, and collaboration among stakeholders.ConclusionPublic health policies have a major role in addressing the interaction between pollution and endometriosis in a long-term commitment.
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