4.8 Article

TAUCON and TAUCOM: A novel biosensor based on fluorescence resonance energy transfer for detecting tau hyperphosphorylation-associated cellular pathologies

Related references

Note: Only part of the references are listed.
Article Geriatrics & Gerontology

Selective Detection of Misfolded Tau From Postmortem Alzheimer's Disease Brains

Ling Wu et al.

Summary: Tau aggregates, present in various tauopathies, have been identified as potential sources for selective detection and biomarker discovery. This study utilized different methods to investigate the role and seeding properties of tau aggregates in different diseases, and demonstrated the species-specific seeding ability of tau aggregates on human tau isoforms. These findings offer potential new biomarkers for the diagnosis of Alzheimer's disease and related tauopathies, and provide new insights into isoform-specific tau aggregation.

FRONTIERS IN AGING NEUROSCIENCE (2022)

Review Biochemistry & Molecular Biology

Mechanisms of secretion and spreading of pathological tau protein

Cecilia A. Brunello et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2020)

Article Biochemistry & Molecular Biology

Modulating disease-relevant tau oligomeric strains by small molecules

Filippa Lo Cascio et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Biosensors for detection of Tau protein as an Alzheimer's disease marker

Mehrdad Ameri et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Neurosciences

Ischemic axonal injury up-regulates MARK4 in cortical neurons and primes tau phosphorylation and aggregation

Eric Y. Hayden et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)

Review Cell Biology

Microtubule-Asssociated Proteins: Structuring the Cytoskeleton

Satish Bodakuntla et al.

TRENDS IN CELL BIOLOGY (2019)

Article Cell Biology

Tauopathy: A common mechanism for neurodegeneration and brain aging

Pampa Saha et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2019)

Article Biochemistry & Molecular Biology

Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains

Liang Qiang et al.

CURRENT BIOLOGY (2018)

Review Neurosciences

Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers

James P. Quinn et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Article Multidisciplinary Sciences

Near-atomic model of microtubule-tau interactions

Elizabeth H. Kellogg et al.

SCIENCE (2018)

Review Neurosciences

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease

Fuyuki Kametani et al.

FRONTIERS IN NEUROSCIENCE (2018)

Review Chemistry, Multidisciplinary

Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks

Eric C. Greenwald et al.

CHEMICAL REVIEWS (2018)

Review Neurosciences

Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability

Alejandra D. Alonso et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2018)

Review Oncology

Tau in neurodegenerative disease

Yong-Lei Gao et al.

ANNALS OF TRANSLATIONAL MEDICINE (2018)

Review Biochemistry & Molecular Biology

Degradation or aggregation: the ramifications of post-translational modifications on tau

Seoyoung Park et al.

BMB REPORTS (2018)

Article Biochemistry & Molecular Biology

Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking

Youssra K. Al-Hilaly et al.

JOURNAL OF MOLECULAR BIOLOGY (2017)

Article Multidisciplinary Sciences

Cryo-EM structures of tau filaments from Alzheimer's disease

Anthony W. P. Fitzpatrick et al.

NATURE (2017)

Article Neurosciences

Truncation of Tau Protein and its Pathological Significance in Alzheimer's Disease

Francisco García-Sierra et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Review Oncology

Regulation of paclitaxel activity by microtubule-associated proteins in cancer chemotherapy

Xingjuan Shi et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2017)

Review Neurosciences

Tau in physiology and pathology

Yipeng Wang et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Article Chemistry, Physical

The effect of multivalent cations and Tau on paclitaxel-stabilized microtubule assembly, disassembly, and structure

Cyrus R. Safinya et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2016)

Review Neurosciences

Tau and tauopathies

Thomas Arendt et al.

BRAIN RESEARCH BULLETIN (2016)

Review Multidisciplinary Sciences

Decoding ALS: from genes to mechanism

J. Paul Taylor et al.

NATURE (2016)

Review Multidisciplinary Sciences

The road to restoring neural circuits for the treatment of Alzheimer's disease

Rebecca G. Canter et al.

NATURE (2016)

Review Multidisciplinary Sciences

Ageing, neurodegeneration and brain rejuvenation

Tony Wyss-Coray

NATURE (2016)

Review Multidisciplinary Sciences

Defects in trafficking bridge Parkinson's disease pathology and genetics

Asa Abeliovich et al.

NATURE (2016)

Article Neurosciences

A Simple Model to Study Tau Pathology

Alexander L. Houck et al.

JOURNAL OF EXPERIMENTAL NEUROSCIENCE (2016)

Article Biochemistry & Molecular Biology

Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors

Sungsu Lim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Article Biochemistry & Molecular Biology

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

Sang-Won Min et al.

NATURE MEDICINE (2015)

Review Cell Biology

Intrinsically disordered proteins in cellular signalling and regulation

Peter E. Wright et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Article Multidisciplinary Sciences

Stathmin Potentiates Vinflunine and Inhibits Paclitaxel Activity

Soazig Malesinski et al.

PLOS ONE (2015)

Review Chemistry, Analytical

Fluorescent Proteins as Genetically Encoded FRET Biosensors in Life Sciences

Bernhard Hochreiter et al.

SENSORS (2015)

Article Biochemistry & Molecular Biology

Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates

Benjamin Falcon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Multidisciplinary Sciences

Proteopathic tau seeding predicts tauopathy in vivo

Brandon B. Holmes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Clinical Neurology

Targeting heat shock proteins to modulate alpha-synuclein toxicity

Daryl Rhys Jones et al.

THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2014)

Review Biochemistry & Molecular Biology

Cell-based Models To Investigate Tau Aggregation

Sungsu Lim et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2014)

Article Neurosciences

Synaptic alterations in the rTg4510 mouse model of tauopathy

Katherine J. Kopeikina et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2013)

Article Clinical Neurology

Spatial patterns of the tau pathology in progressive supranuclear palsy

Richard A. Armstrong et al.

NEUROLOGICAL SCIENCES (2013)

Article Neurosciences

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Alix de Calignon et al.

NEURON (2012)

Article Medicine, Research & Experimental

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

Eva-Maria Mandelkow et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Article Biochemical Research Methods

Conformations of Microtubule-Associated Protein Tau Mapped by Fluorescence Resonance Energy Transfer

Sadasivam Jeganathan et al.

AMYLOID PROTEINS: METHODS AND PROTOCOLS, SECOND EDITION (2012)

Article Neurosciences

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

Cristian A. Lasagna-Reeves et al.

MOLECULAR NEURODEGENERATION (2011)

Review Biochemistry & Molecular Biology

Tau oligomers and aggregation in Alzheimer's disease

Marco A. Meraz-Rios et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Review Clinical Neurology

Mechanisms of tau-induced neurodegeneration

Khalid Iqbal et al.

ACTA NEUROPATHOLOGICA (2009)

Article Neurosciences

Biphasic Effects of Forskolin on Tau Phosphorylation and Spatial Memory in Rats

Qing Tian et al.

JOURNAL OF ALZHEIMERS DISEASE (2009)

Review Neurosciences

The role of tau in neurodegeneration

Tania F. Gendron et al.

MOLECULAR NEURODEGENERATION (2009)

Article Geriatrics & Gerontology

Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease

AL Guillozet-Bongaarts et al.

NEUROBIOLOGY OF AGING (2005)

Review Biochemistry & Molecular Biology

Tau, tangles, and Alzheimer's disease

LI Binder et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Article Biochemistry & Molecular Biology

Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain

SJ Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Control of microtubule stability by the RASSF1A tumor suppressor

LM Liu et al.

ONCOGENE (2003)

Article Neurosciences

Conformational changes and truncation of tau protein during tangle evolution in Alzheimer's disease

Francisco Garcia-Sierra et al.

JOURNAL OF ALZHEIMERS DISEASE (2003)

Review Multidisciplinary Sciences

Biomedicine - Toxic proteins in neurodegenerative disease

JP Taylor et al.

SCIENCE (2002)

Article Multidisciplinary Sciences

Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments

AD Alonso et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)