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Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells
Geylani Can et al.
HEMATOLOGY (2011)
The Zinc Ionophore PCI-5002 Radiosensitizes Non-small Cell Lung Cancer Cells by Enhancing Autophagic Cell Death
Kwang Woon Kim et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
Ligia C. Gomes et al.
NATURE CELL BIOLOGY (2011)
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
Maria M. Mihaylova et al.
NATURE CELL BIOLOGY (2011)
Chemical modulators of autophagy as biological probes and potential therapeutics
Angeleen Fleming et al.
NATURE CHEMICAL BIOLOGY (2011)
Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study
S. Shen et al.
ONCOGENE (2011)
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
Daniel F. Egan et al.
SCIENCE (2011)
Glutaminolysis yields a metabolic by-product that stimulates autophagy
Christina H. Eng et al.
AUTOPHAGY (2010)
ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy
Liang Qin et al.
AUTOPHAGY (2010)
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes
Paola Marambio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Understanding the lethal drivers of tumor-stroma co-evolution Emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment
Michael P. Lisanti et al.
CANCER BIOLOGY & THERAPY (2010)
The autophagic tumor stroma model of cancer or battery-operated tumor growth A simple solution to the autophagy paradox
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Autophagy in cancer associated fibroblasts promotes tumor cell survival Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation Implications for breast cancer and DCIS therapy with autophagy inhibitors
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Hypoxia-induced autophagy: cell death or cell survival?
Nathalie M. Mazure et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Autophagy and tumorigenesis
Nan Chen et al.
FEBS LETTERS (2010)
Autophagy and the Integrated Stress Response
Guido Kroemer et al.
MOLECULAR CELL (2010)
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
Amar J. Majmundar et al.
MOLECULAR CELL (2010)
Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia
Nathalie M. Mazure et al.
AUTOPHAGY (2009)
Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts
Charlotte Anderberg et al.
CANCER RESEARCH (2009)
The reverse Warburg effect Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
Stephanos Pavlides et al.
CELL CYCLE (2009)
The Double-Edged Sword of Autophagy Modulation in Cancer
Eileen White et al.
CLINICAL CANCER RESEARCH (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
Gregory Bellot et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism
Xin-Hua Liao et al.
AMINO ACIDS (2008)
Synthesis and anticancer properties of water-soluble zinc ionophores
Darren Magda et al.
CANCER RESEARCH (2008)
The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy
Jiefei Geng et al.
EMBO REPORTS (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
Yoshinori Takahashi et al.
NATURE CELL BIOLOGY (2007)
Detection and characterization of tumor hypoxia using pO2 histography
Peter Vaupel et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling
Kwang Woon Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
Kurt Degenhardt et al.
CANCER CELL (2006)
Adding chloroquine to conventional treatment for glioblastoma multiforme -: A randomized, double-blind, placebo-controlled trial
J Sotelo et al.
ANNALS OF INTERNAL MEDICINE (2006)
Autophagy: molecular machinery for self-eating
T Yorimitsu et al.
CELL DEATH AND DIFFERENTIATION (2005)
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
Norihiko Furuya et al.
AUTOPHAGY (2005)
Hypoxia and anemia: effects on tumor biology and treatment resistance
P Vaupel et al.
TRANSFUSION CLINIQUE ET BIOLOGIQUE (2005)
Expression of transforming growth factor-beta 1 and growth in soft agar differentiate prostate carcinoma-associated fibroblasts from normal prostate fibroblasts
IFS Francisco et al.
INTERNATIONAL JOURNAL OF CANCER (2004)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)