Current Situation and Causes Analysis of Cadmium Pollution in the Kakehashi River Basin

Cadmium (Cd) pollution is a public environmental problem worthy of attention. Long-term exposure to Cd may have adverse effects on human health. Our previous study showed that urinary concentration of Cd (U-Cd) in the residents decreased when Cd-polluted paddy soil was removed. However, from 2008 to 2014, the concentration of U-Cd increased. At the same time, the concentration of urinary beta(2)-microglobulin (beta(2)-MG), which is considered to be an early sign of cadmium-induced renal dysfunction, increased continuously. To find the cause of elevated urinary cadmium (U-Cd) in residents of cadmiumcontaminated areas, we measured the concentration of cadmium in the blood (B-Cd) of 29 elderly residents (15 female and 14 male) and edible rice (R-Cd), and correlations between R-Cd, B-Cd, and U-Cd were analyzed in the formerly cadmiumpolluted areas (the Kakehashi River basin). In 2016, we collected blood, urine, and rice samples from each participant. The analysis showed a significant correlation between age and B-Cd, U-Cd, and beta(2)-MG. However, there was no significant correlation between R-Cd and U-Cd, B-Cd, or beta(2)-MG concentrations. Although we found a slightly higher level of Cd in rice and urine than reported in 2008, we cannot be sure that it indicates an increased Cd contamination in the Kakehashi River basin because larger studies are required for such a conclusion. The increased urinary Cd concentrations in this area may be because Cd in tissues and organs returns to blood and urine as participants age, which leads to an increasing trend.

Automated summary

Cadmium pollution is a concerning environmental problem that has adverse effects on human health. Despite the removal of cadmium-polluted paddy soil, the concentration of urinary cadmium in residents has increased, along with the concentration of urinary beta(2)-microglobulin, an early sign of cadmium-induced renal dysfunction. Age shows a significant correlation with blood cadmium, urinary cadmium, and beta(2)-microglobulin.