Related references
Note: Only part of the references are listed.Update on genetics of amyotrophic lateral sclerosis
David Brenner et al.
CURRENT OPINION IN NEUROLOGY (2022)
Central nervous system cholesterol metabolism in health and disease
Wan Y. Ho et al.
IUBMB LIFE (2022)
Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine
Ira Agrawal et al.
TRANSLATIONAL NEURODEGENERATION (2022)
Altered TDP-43 Structure and Function: Key Insights into Aberrant RNA, Mitochondrial, and Cellular and Systemic Metabolism in Amyotrophic Lateral Sclerosis
Leanne Jiang et al.
METABOLITES (2022)
The Role of Sphingomyelin and Ceramide in Motor Neuron Diseases
Gavin McCluskey et al.
JOURNAL OF PERSONALIZED MEDICINE (2022)
Mammalian lipids: structure, synthesis and function
Shamshad Cockcroft
UNDERSTANDING BIOCHEMISTRY 7 (2021)
Cell Stress Induces Mislocalization of Transcription Factors with Mitochondrial Enrichment
Chiara Rossi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Changes to the TDP-43 and FUS Interactomes Induced by DNA Damage
Tetsuya Kawaguchi et al.
JOURNAL OF PROTEOME RESEARCH (2020)
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger et al.
NATURE NEUROSCIENCE (2020)
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
Chien-Hsiung Yu et al.
CELL (2020)
The role of TDP-43 mislocalization in amyotrophic lateral sclerosis
Terry R. Suk et al.
MOLECULAR NEURODEGENERATION (2020)
Ceramide contributes to pathogenesis and may be targeted for therapy in VCP inclusion body myopathy
Lan Weiss et al.
HUMAN MOLECULAR GENETICS (2020)
The silence of the fats: A MAM's story about Alzheimer
Rishi R. Agrawal et al.
NEUROBIOLOGY OF DISEASE (2020)
TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration
Ju Gao et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2019)
Altered interplay between endoplasmic reticulum and mitochondria in Charcot-Marie-Tooth type 2A neuropathy
Nathalie Bernard-Marissal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The Inner Nuclear Membrane Is a Metabolically Active Territory that Generates Nuclear Lipid Droplets
Anete Romanauska et al.
CELL (2018)
Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death
Saverio Marchi et al.
CELL CALCIUM (2018)
Endoplasmic reticulum chaperones tweak the mitochondrial calcium rheostat to control metabolism and cell death
Tomas Gutierrez et al.
CELL CALCIUM (2018)
Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Jonathan R. Friedman et al.
DEVELOPMENTAL CELL (2018)
Pathomechanisms of TDP-43 in neurodegeneration
Ju Gao et al.
JOURNAL OF NEUROCHEMISTRY (2018)
Calcium Dynamics as a Machine for Decoding Signals
Carlotta Giorgi et al.
TRENDS IN CELL BIOLOGY (2018)
STIM1 deficiency is linked to Alzheimer's disease and triggers cell death in SH-SY5Y cells by upregulation of L-type voltage-operated Ca2+ entry
Carlos Pascual-Caro et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2018)
Intracellular and Plasma Membrane Events in Cholesterol Transport and Homeostasis
Dmitry Y. Litvinov et al.
JOURNAL OF LIPIDS (2018)
The role of endoplasmic reticulum stress in neurodegenerative disease
Chunchen Xiang et al.
APOPTOSIS (2017)
Mitochondrial lipids in neurodegeneration
Andreas Aufschnaiter et al.
CELL AND TISSUE RESEARCH (2017)
Cytosolic proteostasis through importing of misfolded proteins into mitochondria
Linhao Ruan et al.
NATURE (2017)
The ER proteostasis network in ALS: Determining the differential motoneuron vulnerability
Pablo Rozas et al.
NEUROSCIENCE LETTERS (2017)
Contacts between the endoplasmic reticulum and other membranes in neurons
Yumei Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
TDP-43 stabilises the processing intermediates of mitochondrial transcripts
Keiichi Izumikawa et al.
SCIENTIFIC REPORTS (2017)
Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease
Marta Pera et al.
EMBO JOURNAL (2017)
Of yeast, mice and men: MAMs come in two flavors
Maria Sol Herrera-Cruz et al.
BIOLOGY DIRECT (2017)
Mitochondria-associated membranes as hubs for neurodegeneration
Michiel Krols et al.
ACTA NEUROPATHOLOGICA (2016)
Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways
Anna M. Blokhuis et al.
ACTA NEUROPATHOLOGICA (2016)
Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS
Seiji Watanabe et al.
EMBO MOLECULAR MEDICINE (2016)
ALS/FTD-associated FUS activates GSK-3 to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations
Radu Stoica et al.
EMBO REPORTS (2016)
The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
Wenzhang Wang et al.
NATURE MEDICINE (2016)
Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis
Giovanni Manfredi et al.
NEUROBIOLOGY OF DISEASE (2016)
Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice
Aleix Sala-Vila et al.
SCIENTIFIC REPORTS (2016)
Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications
Carlotta Giorgi et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration
Nathalie Bernard-Marissal et al.
BRAIN (2015)
Age-Dependent TDP-43-Mediated Motor Neuron Degeneration Requires GSK3, hat-trick, and xmas-2
Jemeen Sreedharan et al.
CURRENT BIOLOGY (2015)
ER-mitochondria contact sites in yeast: beyond the myths of ERMES
Alexander Lang et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Role of sigma-1 receptors in neurodegenerative diseases
Linda Nguyen et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2015)
A SIGMAR1 splice-site mutation causes distal hereditary motor neuropathy
Xiaobo Li et al.
NEUROLOGY (2015)
The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity
Quan Li et al.
NATURE COMMUNICATIONS (2015)
Novel subcellular localization for α-synuclein: possible functional consequences
Cristina Guardia-Laguarta et al.
FRONTIERS IN NEUROANATOMY (2015)
Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Regulates Steroidogenic Activity via Steroidogenic Acute Regulatory Protein (StAR)-Voltage-dependent Anion Channel 2 (VDAC2) Interaction
Manoj Prasad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1
Evangelos Kiskinis et al.
CELL STEM CELL (2014)
FAD2 and FAD3 Desaturases Form Heterodimers That Facilitate Metabolic Channeling in Vivo
Ying Lou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances
J. T. Vollrath et al.
CELL DEATH & DISEASE (2014)
ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
Radu Stoica et al.
NATURE COMMUNICATIONS (2014)
PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy
Simone Patergnani et al.
AUTOPHAGY (2013)
Mfn2 modulates the UPR and mitochondrial function via repression of PERK
Juan Pablo Munoz et al.
EMBO JOURNAL (2013)
The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons
Wenzhang Wang et al.
HUMAN MOLECULAR GENETICS (2013)
Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis
J. Prause et al.
HUMAN MOLECULAR GENETICS (2013)
Analysis of the protein network of cholesterol homeostasis in different brain regions: An age and sex dependent perspective
Marco Segatto et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2013)
In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM)
Chloe N. Poston et al.
JOURNAL OF PROTEOMICS (2013)
Mitochondria-associated ER membranes in Alzheimer disease
Eric A. Schon et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2013)
MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2
Ayumu Sugiura et al.
MOLECULAR CELL (2013)
Autophagosomes form at ER-mitochondria contact sites
Maho Hamasaki et al.
NATURE (2013)
Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress
Diane Moujalled et al.
PLOS ONE (2013)
ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation
Adam K. Walker et al.
PLOS ONE (2013)
Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models
Louise Hedskog et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology
Charles Betz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The role of cholesterol in the association of endoplasmic reticulum membranes with mitochondria
Michiko Fujimoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
T. Verfaillie et al.
CELL DEATH AND DIFFERENTIATION (2012)
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
Estela Area-Gomez et al.
EMBO JOURNAL (2012)
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
Kurt J. De Vos et al.
HUMAN MOLECULAR GENETICS (2012)
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
Gabor M. Morotz et al.
HUMAN MOLECULAR GENETICS (2012)
TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression
Hiroaki Suzuki et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2012)
Endoplasmic reticulum-mitochondria contacts: function of the junction
Ashley A. Rowland et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Mitochondrial dysfunction in ALS
Mauro Cozzolino et al.
PROGRESS IN NEUROBIOLOGY (2012)
The dynamic relationships between the three events that release individual Na+ ions from the Na+/K+-ATPase
David C. Gadsby et al.
NATURE COMMUNICATIONS (2012)
Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS
Victoria Ayala et al.
ACTA NEUROPATHOLOGICA (2011)
A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis
Amr Al-Saif et al.
ANNALS OF NEUROLOGY (2011)
Calcium signaling around Mitochondria Associated Membranes (MAMs)
Simone Patergnani et al.
CELL COMMUNICATION AND SIGNALING (2011)
A Highly Dynamic ER-Derived Phosphatidylinositol-Synthesizing Organelle Supplies Phosphoinositides to Cellular Membranes
Yeun Ju Kim et al.
DEVELOPMENTAL CELL (2011)
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
Ryota Iwasawa et al.
EMBO JOURNAL (2011)
Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation
Surendra S. Ambegaokar et al.
HUMAN MOLECULAR GENETICS (2011)
Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
Karen M. Doyle et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Quantitative Proteomic Analyses of Human Cytomegalovirus-Induced Restructuring of Endoplasmic Reticulum-Mitochondrial Contacts at Late Times of Infection
Aiping Zhang et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis
L. M. Duffy et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2011)
ER Tubules Mark Sites of Mitochondrial Division
Jonathan R. Friedman et al.
SCIENCE (2011)
Oxidative protein folding in the endoplasmic reticulum: Tight links to the mitochondria-associated membrane (MAM)
Thomas Simmen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)
Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
Cesar Cardenas et al.
CELL (2010)
Identification and Characterization of Murine Mitochondria-associated Neutral Sphingomyelinase (MA-nSMase), the Mammalian Sphingomyelin Phosphodiesterase 5
Bill X. Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway
Karine Langou et al.
JOURNAL OF NEUROCHEMISTRY (2010)
VDAC, a multi-functional mitochondrial protein regulating cell life and death
Varda Shoshan-Barmatz et al.
MOLECULAR ASPECTS OF MEDICINE (2010)
Detergent-Resistant Microdomains Determine the Localization of σ-1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction
Teruo Hayashi et al.
MOLECULAR PHARMACOLOGY (2010)
Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS
Adrian Israelson et al.
NEURON (2010)
THE SIGMA-1 RECEPTOR IS ENRICHED IN POSTSYNAPTIC SITES OF C-TERMINALS IN MOUSE MOTONEURONS. AN ANATOMICAL AND BEHAVIORAL STUDY
T. A. Mavlyutov et al.
NEUROSCIENCE (2010)
Alterations in subcellular localization of TDP-43 immunoreactivity in the anterior horns in sporadic amyotrophic lateral sclerosis
Shoichi Sasaki et al.
NEUROSCIENCE LETTERS (2010)
Lipid Rafts As a Membrane-Organizing Principle
Daniel Lingwood et al.
SCIENCE (2010)
Acyl-coenzyme A: cholesterol acyltransferases
Ta-Yuan Chang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: The role of Ras
Olga Martins de Brito et al.
MITOCHONDRION (2009)
GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis
Renata Sano et al.
MOLECULAR CELL (2009)
A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice
Smita Saxena et al.
NATURE NEUROSCIENCE (2009)
VAPB interacts with and modulates the activity of ATF6
Christos Gkogkas et al.
HUMAN MOLECULAR GENETICS (2008)
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
Olga Martins de Brito et al.
NATURE (2008)
Sigma-1 receptor chaperones at the ER-Mitochondrion interface regulate Ca2+ signaling and cell survival
Teruo Hayashi et al.
CELL (2007)
Fatty acid transport protein 4 is the principal very long chain fatty Acyl-CoA synthetase in skin fibroblasts
Zhenzhen Jia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels
Gyorgy Szabadkai et al.
JOURNAL OF CELL BIOLOGY (2006)
被撤回的出版物: Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1 (Retracted article. See vol. 292, pg. 12007, 2017)
Julie D. Atkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Structural and functional features and significance of the physical linkage between ER and mitochondria
Gyorgy Csordas et al.
JOURNAL OF CELL BIOLOGY (2006)
The type III inositol 1,4,5-trisphosphate receptor preferentially transmits apoptotic Ca2+ signals into mitochondria
CCP Mendes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
T Simmen et al.
EMBO JOURNAL (2005)
Phosphatidylserine transport to the mitochondria is regulated by ubiquitination
MM Schumacher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Phosphatidylserine synthase-1 and-2 are localized to mitochondria-associated membranes
SJ Stone et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
