4.5 Article

Targeted expression of a designed fusion protein containing BMP2 into the lumen of exosomes

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Autophagy regulation by RNA alternative splicing and implications in human diseases

Patricia Gonzalez-Rodriguez et al.

Summary: This article reviews the regulatory role of RNA alternative splicing in autophagy and its relevance to diseases. It also discusses the therapeutic strategies of targeting alternative splicing and autophagy as well as selectively regulating autophagy-related protein isoforms.

NATURE COMMUNICATIONS (2022)

Review Cell Biology

Application of engineered extracellular vesicles for targeted tumor therapy

Fusheng Zhang et al.

Summary: All cells can release extracellular vesicles (EVs) containing various cellular components, which are crucial for intercellular communication and maintaining internal homeostasis. EVs have shown great potential in drug delivery and precision therapy due to their targeting specificity and regulatory ability. They can modulate immune system function by influencing the tumor microenvironment and can be combined with other delivery systems to enhance drug delivery efficiency.

JOURNAL OF BIOMEDICAL SCIENCE (2022)

Article Engineering, Biomedical

Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration

Xiao Xu et al.

Summary: Targeted delivery of Kartogenin (KGN) to synovial fluid-derived mesenchymal stem cells (SF-MSCs) by engineered exosomes increases its effective concentration in the cell, enhancing chondrogenesis in vitro and in vivo.

BIOMATERIALS (2021)

Review Endocrinology & Metabolism

Bone morphogenetic proteins (BMPs) in the central regulation of energy balance and adult neural plasticity

Gabriel S. Jensen et al.

Summary: Research indicates that bone morphogenetic proteins regulate metabolic health by controlling neural plasticity in both the brain and peripheral tissues, impacting energy intake and expenditure. This role helps in understanding metabolic regulation and offers insights into weight loss mechanisms.

METABOLISM-CLINICAL AND EXPERIMENTAL (2021)

Review Medicine, Research & Experimental

Engineering exosomes for targeted drug delivery

Yujie Liang et al.

Summary: Exosomes can be engineered through genetic and chemical methods for targeted drug delivery, increasing the local concentration of therapeutics and minimizing side effects.

THERANOSTICS (2021)

Review Environmental Sciences

Exosome engineering: Current progress in cargo loading and targeted delivery

Shengyang Fu et al.

NANOIMPACT (2020)

Review Cell Biology

Mast cell chymase: morphofunctional characteristics

Dmitri Atiakshin et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2019)

Review Medicine, Research & Experimental

Exosome as a Novel Shuttle for Delivery of Therapeutics across Biological Barriers

Chandan Kanta Das et al.

MOLECULAR PHARMACEUTICS (2019)

Article Biochemistry & Molecular Biology

Vesiclepedia 2019:a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles

Mohashin Pathan et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Medicine, Research & Experimental

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia

Jialei Yang et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2017)

Article Biochemistry & Molecular Biology

Metalloproteinases in extracellular vesicles

Masayuki Shimoda et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)

Review Biochemistry & Molecular Biology

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

Mercedes Tkach et al.

Article Biochemistry & Molecular Biology

ExoCarta: A Web-Based Compendium of Exosomal Cargo

Shivakumar Keerthikumar et al.

JOURNAL OF MOLECULAR BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Stabilization of Exosome-targeting Peptides via Engineered Glycosylation

Michelle E. Hung et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Review Cell Biology

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

Emanuele Cocucci et al.

TRENDS IN CELL BIOLOGY (2015)

Review Spectroscopy

Proteomics of extracellular vesicles: Exosomes and ectosomes

Dong-Sic Choi et al.

MASS SPECTROMETRY REVIEWS (2015)

Article Cell Biology

Optimized exosome isolation protocol for cell culture supernatant and human plasma

Richard J. Lobb et al.

JOURNAL OF EXTRACELLULAR VESICLES (2015)

Review Cell & Tissue Engineering

TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation

Md Shaifur Rahman et al.

BONE RESEARCH (2015)

Review Biochemistry & Molecular Biology

Bone Morphogenetic Proteins: Structure, biological function and therapeutic applications

Ana Claudia Carreira et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2014)

Review Biochemical Research Methods

Proteolytic factors in exosomes

Masayuki Shimoda et al.

PROTEOMICS (2013)

Article Cell Biology

EVpedia: an integrated database of high-throughput data for systemic analyses of extracellular vesicles

Dae-Kyum Kim et al.

JOURNAL OF EXTRACELLULAR VESICLES (2013)

Article Biochemical Research Methods

Exosome-mediated delivery of siRNA in vitro and in vivo

Samir El-Andaloussi et al.

NATURE PROTOCOLS (2012)

Article Biochemistry & Molecular Biology

ExPASy: SIB bioinformatics resource portal

Panu Artimo et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Cell Biology

Endocytic sorting of transmembrane protein cargo

Bernard T. Kelly et al.

CURRENT OPINION IN CELL BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Sorting of lysosomal proteins

Thomas Braulke et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)

Review Biochemical Research Methods

Exosomes: proteomic insights and diagnostic potential

Richard J. Simpson et al.

EXPERT REVIEW OF PROTEOMICS (2009)

Article Biochemical Research Methods

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

Robert H. Kutner et al.

NATURE PROTOCOLS (2009)

Review Cell Biology

Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes

Maria Yanez-Mo et al.

TRENDS IN CELL BIOLOGY (2009)

Review Cell Biology

Shedding microvesicles: artefacts no more

Emanuele Cocucci et al.

TRENDS IN CELL BIOLOGY (2009)

Review Biochemical Research Methods

Proteomic profiling of exosomes: Current perspectives

Richard J. Simpson et al.

PROTEOMICS (2008)

Meeting Abstract Allergy

Analysis of global protein content in mast cell exosomes

K Ekström et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)

Article Biochemistry & Molecular Biology

Molecular recognition of BMP-2 and BMP receptor IA

S Keller et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)

Review Cell Biology

Protein sorting into multivesicular endosomes

C Raiborg et al.

CURRENT OPINION IN CELL BIOLOGY (2003)

Review Immunology

Exosomes:: Composition, biogenesis and function

C Théry et al.

NATURE REVIEWS IMMUNOLOGY (2002)

Article Biotechnology & Applied Microbiology

Determination of protease cleavage site motifs using mixture-based oriented peptide libraries

BE Turk et al.

NATURE BIOTECHNOLOGY (2001)