4.7 Article

Magnetic metal-organic framework nanocomposites for enrichment and direct detection of small molecules by negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 42, Pages 8785-8788

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc02495a

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Funding

  1. National Natural Science Foundation of China [21375018, 21175025]

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Zeolitic imidazolate framework-8 coated magnetic nanocomposites (Fe3O4@ZIF-8 MNCs) served as an absorbent and a matrix for negativeion MALDI-TOF MS. The host-guest property and interference-free background made them an ideal dual platform for the sensitive analysis of small molecules.

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