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Erythrocyte glutathione transferase. A sensitive Up-Down biomarker of environmental and industrial pollution

Journal

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Volume 750, Issue -, Pages -

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.abb.2023.109786

Keywords

Glutathione; Glutathione transferase; Biomarker; Environmental pollution; Industrial pollution; Animal model

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Erythrocyte glutathione transferase, a well-known biomarker of environmental pollution, reveals both chronic and acute contamination. Its unique molecular and kinetic properties distinguish it from other enzymes used as biomarkers for environmental contamination.
Erythrocyte glutathione transferase is a well-known biomarker of environmental pollution. Examination of the extensive scientific literature discovers an atypical and very interesting property of this enzyme which may reveal a chronic exposition to many contaminants but in some cases even an acute and short-term dangerous contamination. This review also underlines the peculiar molecular and kinetic properties of this enzyme which makes it unique in the panorama of enzymes used as biomarker for environmental contamination.

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