4.6 Letter

Risk factors for fractures following liver transplantation: a population-based cohort study

Related references

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Article Medicine, General & Internal

Risk factors for fractures following liver transplantation: a population-based cohort study

Jei-Wen Chang et al.

Summary: This study identified risk factors for post-transplant fractures in liver transplant recipients, especially those who were aged ≥65 years, female, hepatitis C carriers, had a history of fractures within 1 year prior to transplant, alcoholism, and higher daily prednisolone dose. The use of tacrolimus and sirolimus/everolimus was associated with a decreased risk of fractures. The findings highlight the importance of identifying high-risk individuals and implementing preventive measures.

ANNALS OF MEDICINE (2023)

Article Endocrinology & Metabolism

Blood Pressure Variability and the Risk of Fracture: A Nationwide Cohort Study

Jung Eun Yoo et al.

Summary: A positive association was found between higher blood pressure variability (BPV) and incidence of fractures in this retrospective cohort study involving over 3 million participants. BPV was identified as an independent predictor for developing fractures, with consistent results noted for vertebral fractures and hip fractures in various subgroup analyses.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Article Gastroenterology & Hepatology

Blood Pressure Variability Early After Liver Transplantation Predicts Long-Term Mortality

Katie Truitt et al.

Summary: This study found that increased systolic blood pressure variability in liver transplant recipients is associated with decreased mortality, especially in men, patients with pre-transplant atherosclerotic cardiovascular disease, or patients without pre-transplant diabetes. There was no significant association with cardiovascular events. Diastolic blood pressure variability did not show a significant effect on cardiovascular events or mortality.

LIVER TRANSPLANTATION (2022)