4.5 Review

Long Noncoding RNAs in Metabolic Syndrome Related Disorders

Journal

MEDIATORS OF INFLAMMATION
Volume 2016, Issue -, Pages -

Publisher

HINDAWI LTD
DOI: 10.1155/2016/5365209

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Funding

  1. National Science Centre [2013/11/B/NZZ/00125]
  2. Ministry of Science and Higher Education
  3. [BMN7/2016]

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Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands.

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