Facile synthesis of core-shell Co-MOF with hierarchical porosity for enhanced electrochemical detection of furaltadone in aquaculture water

Metal-organic frameworks (MOFs) exhibited huge application potential in electrochemical analysis field, how to facilely and effectively boost the electrochemical sensing activity of MOFs materials still face enormous chal-lenges. In this work, core-shell Co-MOF (Co-TCA@ZIF-67) polyhedrons with hierarchical porosity was easily synthesized via simple chemical etching reaction by selecting thiocyanuric acid as the etching reagent. Benefiting from the introduction of mesopores and thiocyanuric acid/Co2+ complex on the surface of ZIF-67 frameworks, the property and functions of the pristine ZIF-67 was seriously tailored. Compared with the pristine ZIF-67, the as-resulted Co-TCA@ZIF-67 nanoparticles displayed greatly enhanced physical adsorption capacity and elec-trochemical reduction activity toward the antibiotic drug furaltadone. As a result, a novel furaltadone electro-chemical sensor with high sensitivity was fabricated. The linear detection range was from 50 nM to 5 mu M with sensitivity of 110.40 mu A-1 mu M-1 cm-2 and detection limit of 12 nM. This work demonstrated chemical etching strategy is truly a facile and effective way to modify the electrochemical sensing performance of MOFs-based materials, and we believed the chemically etched MOFs materials will play a stronger role in terms of food safety and environmental conservation.

Automated summary

A core-shell Co-MOF (Co-TCA@ZIF-67) nanoparticles with hierarchical porosity was synthesized via a simple chemical etching reaction, which greatly enhanced the physical adsorption capacity and electrochemical reduction activity of the material. A high sensitivity furaltadone electrochemical sensor was fabricated using the as-resulted Co-TCA@ZIF-67 nanoparticles.